Search
Results: 597
Neural Population Dynamics Underlying Encoding of Time in the Cortico-Striatal Circuit
Francisca Martínez Traub
Jan 01, 0001
Interval timing, the ability to accurately measure elapsed time between events, is critical for generating appropriate behavioral responses. Research conducted over the past decades has implicated the cortico-striatal-thalamic...
Published by: Rockefeller University
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Anne-Valérie Burgener, Glenn R Bantug, Benedikt J Meyer, Rebecca Higgins, Adhideb Ghosh, Olivier Bignucolo, Eric H Ma, Jordan Loeliger, Gunhild Unterstab, Marco Geigges, Rebekah Steiner, Michel Enamorado, Robert Ivanek, Danielle Hunziker, Alexander Schmidt, Bojana Müller-Durovic, Jasmin Grählert, Raja Epple, Sarah Dimeloe, Jonas Lötscher, Ursula Sauder, Monika Ebnöther, Bettina Burger, Ingmar Heijnen, Sarai Martínez-Cano, Nathan Cantoni, Rolf Brücker, Christian R Kahlert, David Sancho, Russell G Jones, Alexander Navarini, Mike Recher, Christoph Hess
Sep 27, 2019
Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the extracellular acidification rate as a measure of glycolysis and the oxygen...
Anti-Inflammatory Agents B-Lymphocytes Cell Respiration Cells Cultured Electron Transport Complex II Fumarates Glycolysis Humans Inflammation Interleukin-6 Kelch-Like ECH-Associated Protein 1 Lymphocytosis Mitochondria Mutation NF-E2-Related Factor 2 Oxygen Consumption Prospective Studies Signal Transduction Exome Sequencing
G-quadruplexes are transcription factor binding hubs in human chromatin
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Apr 23, 2021
Abstract: Background: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but many...
G-quadruplexes are transcription factor binding hubs in human chromatin.
Jochen Spiegel, Sergio Martínez Cuesta, Santosh Adhikari, Robert Hänsel-Hertsch, David Tannahill, Shankar Balasubramanian
Mar 26, 2021
Missing the missing values
Abstract: Nowadays, there is an increasing concern in machine learning about the causes underlying unfair decision making, that is, algorithmic decisions discriminating some groups over others, especially with groups that are...
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Crystallization kinetic Monte Carlo Nanocomposite Polycrystal Thin film deposition /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces
Crystallization processes in bi-component thin film depositions:
The kinetic Monte Carlo (KMC) method is a powerful and simple tool to simulate the growth of thin films by deposition. However, one of its major drawbacks is the artificial order induced by the use of regular lattices. An...
Crystallization kinetic Monte Carlo Nanocomposite Polycrystal Thin film deposition /dk/atira/pure/subjectarea/asjc/1600/1600 name=General Chemistry /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2500/2505 name=Materials Chemistry /dk/atira/pure/subjectarea/asjc/2500/2508 name=Surfaces, Coatings and Films /dk/atira/pure/subjectarea/asjc/3100/3110 name=Surfaces and Interfaces
Quantifying patterns of alcohol consumption and its effects on health and wellbeing among BaYaka hunter-gatherers
Jessica K Knight, Gul Deniz Salali, Gaurav Sikka, Inez Derkx, Sarai M Keestra, Nikhil Chaudhary
Oct 28, 2021
Quantifying patterns of alcohol consumption and its effects on health and wellbeing among BaYaka hunter-gatherers
Jessica K Knight, Gul Deniz Salali, Gaurav Sikka, Inez Derkx, Sarai M Keestra, Nikhil Chaudhary
Jan 06, 2022
Ethnographers frequently allude to alcoholism and related harms in Indigenous hunter-gatherer communities, but very few studies have quantified patterns of alcohol consumption or its health and social impacts. We present a case...
On the Finite Element Implementation of Functionally Graded Materials.
Emilio Martínez-Pañeda
Feb 07, 2019
We investigate the numerical implementation of functionally graded properties in the context of the finite element method. The macroscopic variation of elastic properties inherent to functionally graded materials (FGMs) is...
Jordan’s self-fulfilling prophecy
JC Martínez
Jun 21, 2016
A Unified Abaqus Implementation of the Phase Field Fracture Method Using Only a User Material Subroutine.
We present a simple and robust implementation of the phase field fracture method in Abaqus. Unlike previous works, only a user material (UMAT) subroutine is used. This is achieved by exploiting the analogy between the phase...
Liver organoids reproduce alpha-1 antitrypsin deficiency-related liver disease
Gema Gómez-Mariano, Nerea Matamala, Selene Martínez, Iago Justo, Alberto Marcacuzco, Carlos Jimenez, Sara Monzón, Isabel Cuesta, Cristina Garfia, María Teresa Martínez, Meritxell Huch, Ignacio Pérez de Castro, Manuel Posada, Sabina Janciauskiene, Beatriz Martínez-Delgado
Jun 06, 2020
Abstract: Background and aims: Alpha-1 antitrypsin (AAT) is a product of SERPINA1 gene mainly expressed by hepatocytes. Clinically relevant mutations in the SERPINA1 gene, such as Z (Glu342Lys), results in an expression of...
Tool wear classification using time series imaging and deep learning
Abstract: Tool condition monitoring (TCM) has become essential to achieve high-quality machining as well as cost-effective production. Identification of the cutting tool state during machining before it reaches its failure stage...
Deconstructing a Hermeneutic Presupposition in Ricoeur’s The Symbolism of Evil
Hernán Martínez Millán
Mar 23, 2016
This paper critically analyzes Paul Ricoeurʼs presupposition that Plato’s philosophy was built on Orphism. In order to shed light on this central problematic issue in The Symbolism of Evil, this paper develops the following...
Published by: Memorial University of Newfoundland
Deconstructing a Hermeneutic Presupposition in Ricoeur’s The Symbolism of Evil
Hernán Martínez Millán
Mar 23, 2016
This paper critically analyzes Paul Ricoeurʼs presupposition that Plato’s philosophy was built on Orphism. In order to shed light on this central problematic issue in The Symbolism of Evil, this paper develops the following...
Published by: Memorial University of Newfoundland
A simple and robust Abaqus implementation of the phase field fracture
method
The phase field fracture method is attracting significant interest. Phase
field approaches have enabled predicting - on arbitrary geometries and
dimensions - complex fracture phenomena such as crack branching...
Stifling stateness
This article assesses the impact of the Assad regime's aerial bombardment campaign on a frequently neglected component of Syria's ongoing civil war: rebel governance. While analysis of the military and humanitarian ramifications...
Tool wear classification using time series imaging and deep learning
Tool condition monitoring (TCM) has become essential to achieve high-quality machining as well as cost-effective production. Identification of the cutting tool state during machining before it reaches its failure stage is...
|
|< |
< |
1 |