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Results: 101
Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial.
Bruno Francois, Simon Lambden, Sebastien Gibot, Marc Derive, Aurelie Olivier, Valerie Cuvier, Stephan Witte, Jean-Marie Grouin, Jean Jacques Garaud, Margarita Salcedo-Magguilli, Mitchell Levy, Pierre-François Laterre
Aug 11, 2021
INTRODUCTION: Septic shock is the subgroup of patients with sepsis, which presents as vasopressor dependence, an elevated blood lactate concentration and is associated with a mortality of at least 30%. Expression of the...
Genetic and Pharmacological Inhibition of TREM-1 Limits the Development of Experimental Atherosclerosis.
Jeremie Joffre, Stephane Potteaux, Lynda Zeboudj, Xavier Loyer, Amir Boufenzer, Ludivine Laurans, Bruno Esposito, Marie Vandestienne, Saskia CA de Jager, Carole Hénique, Ivana Zlatanova, Soraya Taleb, Patrick Bruneval, Alain Tedgui, Ziad Mallat, Sebastien Gibot, Hafid Ait-Oufella
Jun 21, 2018
BACKGROUND: Innate immune responses activated through myeloid cells contribute to the initiation, progression, and complications of atherosclerosis in experimental models. However, the critical upstream pathways that link innate...
apolipoprotein foam cells Inflammation macrophage Toll-like receptor Animals Apoptosis Carotid Arteries Carotid Artery Diseases Cells Cultured Disease Models Animal Enzyme-Linked Immunosorbent Assay Genetic Therapy Humans Immunity Innate Lauric Acids MACROPHAGES Male Membrane Glycoproteins Mice Mice Inbred C57BL Mice Transgenic Oligopeptides Plaque Atherosclerotic Receptors Immunologic Rhodamines Triggering Receptor Expressed on Myeloid Cells-1
Spectral analysis of one-dimensional high-contrast elliptic problems with periodic coefficients
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
Spectral analysis of one-dimensional high-contrast elliptic problems with periodic coefficients
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
The Relative Contribution of Executive Functions and Aging on Attentional Control During Road Crossing.
As we age, many physical, perceptual and cognitive abilities decline, which can critically impact our day-to-day lives. However, the decline of many abilities is concurrent; thus, it is challenging to disentangle the relative...
Published by: Frontiers in Psychology
Nutritional and developmental programming effects of insulin.
The discovery of insulin in 1921 was a major breakthrough in medicine and for therapy in patients with diabetes. The dramatic rise in the prevalence of overweight and obesity has been tightly linked to an increased prevalence of...
Assessment of the long-term stability of the polymer of intrinsic microporosity PIM-1 for hydrogen storage applications
Sebastien Rochat, Katarzyna Polak-Kraśna, Mi Tian, Timothy Mays, Christopher Bowen, Andrew Burrows
Jan 01, 2019
Polymers of intrinsic microporosity, such as PIM-1, advantageously combine high surface areas with good processability, which are attractive properties for hydrogen storage applications. Here we address the lack of data on the...
Thermodynamics of high-pressure ice phases explored with atomistic simulations
Aleks Reinhardt, Mandy Bethkenhagen, Federica Coppari, Marius Millot, Sebastien Hamel, Bingqing Cheng
Sep 10, 2022
Most experimentally known high-pressure ice phases have a body-centred cubic (bcc) oxygen lattice. Our large-scale molecular-dynamics simulations with a machine-learning potential indicate that, amongst these bcc ice phases...
Thermodynamics of high-pressure ice phases explored with atomistic simulations
Aleks Reinhardt, Mandy Bethkenhagen, Federica Coppari, Marius Millot, Sebastien Hamel, Bingqing Cheng
Aug 11, 2022
Most experimentally known high-pressure ice phases have a body-centred cubic (bcc) oxygen lattice. Our large-scale molecular-dynamics simulations with a machine-learning potential indicate that, amongst these bcc ice phases...
AFM imaging and nanoindentation of polymer of intrinsic microporosity PIM-1
Katarzyna Polak-Krasna, Carlos Fuhrhop, Sebastien Rochat, Andrew Burrows, Anthimos Georgiadis, Christopher Bowen, Timothy Mays
Sep 14, 2017
Polymers of intrinsic microporosity (PIMs) have promising gas adsorption properties for potential applications such as incorporation into high-pressure hydrogen storage tanks in an effort to increase the storage capacity or...
Reference Genome Anchoring of High-Density Markers for Association Mapping and Genomic Prediction in European Winter Wheat.
Olufunmilayo Ladejobi, Ian J Mackay, Jesse Poland, Sebastien Praud, Julian M Hibberd, Alison R Bentley
Jan 03, 2020
In this study, we anchored genotyping-by-sequencing data to the International Wheat Genome Sequencing Consortium Reference Sequence v1.0 assembly to generate over 40,000 high quality single nucleotide polymorphism markers on a...
Solvent Sorption-Induced Actuation of Composites Based on a Polymer of Intrinsic Microporosity
Katarzyna Polak-Kraśna, Mi Tian, Sebastien Rochat, Nicholas Gathercole, Chenggang Yuan, Zhe Hao, Min Pan, Andrew Burrows, Tim Mays, Chris Bowen
Feb 12, 2021
Materials that are capable of actuation in response to a variety of external stimuli are of significant interest for applications in sensors, soft robotics, and biomedical devices. Here, we present a class of actuators using...
Assessment of the long-term stability of the polymer of intrinsic microporosity PIM-1 for hydrogen storage applications
Sebastien Rochat, Katarzyna Polak-Kraśna, Mi Tian, Timothy Mays, Christopher Bowen, Andrew Burrows
Jan 01, 2019
Polymers of intrinsic microporosity, such as PIM-1, advantageously combine high surface areas with good processability, which are attractive properties for hydrogen storage applications. Here we address the lack of data on the...
AFM imaging and nanoindentation of polymer of intrinsic microporosity PIM-1
Katarzyna Polak-Krasna, Carlos Fuhrhop, Sebastien Rochat, Andrew Burrows, Anthimos Georgiadis, Christopher Bowen, Timothy Mays
Sep 14, 2017
Polymers of intrinsic microporosity (PIMs) have promising gas adsorption properties for potential applications such as incorporation into high-pressure hydrogen storage tanks in an effort to increase the storage capacity or...
Solvent Sorption-Induced Actuation of Composites Based on a Polymer of Intrinsic Microporosity
Katarzyna Polak-Kraśna, Mi Tian, Sebastien Rochat, Nicholas Gathercole, Chenggang Yuan, Zhe Hao, Min Pan, Andrew Burrows, Tim Mays, Chris Bowen
Feb 12, 2021
Materials that are capable of actuation in response to a variety of external stimuli are of significant interest for applications in sensors, soft robotics, and biomedical devices. Here, we present a class of actuators using...
Reference Genome Anchoring of High-Density Markers for Association Mapping and Genomic Prediction in European Winter Wheat.
Olufunmilayo Ladejobi, Ian J Mackay, Jesse Poland, Sebastien Praud, Julian M Hibberd, Alison R Bentley
Jan 03, 2020
In this study, we anchored genotyping-by-sequencing data to the International Wheat Genome Sequencing Consortium Reference Sequence v1.0 assembly to generate over 40,000 high quality single nucleotide polymorphism markers on a...
Sedentary Behavior Research Network (SBRN) - Terminology Consensus Project process and outcome.
Mark S Tremblay, Salomé Aubert, Joel D Barnes, Travis J Saunders, Valerie Carson, Amy E Latimer-Cheung, Sebastien FM Chastin, Teatske M Altenburg, Mai JM Chinapaw, SBRN Terminology Consensus Project Participants
Jul 18, 2018
BACKGROUND: The prominence of sedentary behavior research in health science has grown rapidly. With this growth there is increasing urgency for clear, common and accepted terminology and definitions. Such standardization is...
Genome-wide mutational biases fuel transcriptional diversity in the Mycobacterium tuberculosis complex.
Álvaro Chiner-Oms, Michael Berney, Christine Boinett, Fernando González-Candelas, Douglas B Young, Sebastien Gagneux, William R Jacobs, Julian Parkhill, Teresa Cortes, Iñaki Comas
Oct 01, 2019
The Mycobacterium tuberculosis complex (MTBC) members display different host-specificities and virulence phenotypes. Here, we have performed a comprehensive RNAseq and methylome analysis of the main clades of the MTBC and...
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