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Results: 101
Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs.
David M Sokal, Alex McSloy, Matteo Donegà, Joseph Kirk, Romain A Colas, Nikola Dolezalova, Esteban A Gomez, Isha Gupta, Cathrine T Fjordbakk, Sebastien Ouchouche, Paul B Matteucci, Kristina Schlegel, Rizwan Bashirullah, Dirk Werling, Kim Harman, Alison Rowles, Refet Firat Yazicioglu, Jesmond Dalli, Daniel J Chew, Justin D Perkins
Apr 13, 2021
Neuromodulation of the immune system has been proposed as a novel therapeutic strategy for the treatment of inflammatory conditions. We recently demonstrated that stimulation of near-organ autonomic nerves to the spleen can be...
Autonomic Nervous System bioelectronic medicine endotoxemia Inflammation neuromodulation specialized pro resolving mediators splenic nerve Stimulation Animals Disease Models Animal Electric Stimulation Therapy Electrodes Implanted endotoxemia Female Inflammation Neuroimmunomodulation Splanchnic Nerves Spleen Sus scrofa
Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves
Isha Gupta, Antonino M. Cassará, Ilya Tarotin, Matteo Donega, Jason A. Miranda, David M. Sokal, Sebastien Ouchouche, Wesley Dopson, Paul Matteucci, Esra Neufeld, Matthew A. Schiefer, Alison Rowles, Paul McGill, Justin Perkins, Nikola Dolezalova, Kourosh Saeb-Parsy, Niels Kuster, Refet Firat Yazicioglu, Jason Witherington, Daniel J. Chew
Oct 18, 2021
Abstract: Neuromodulation is a new therapeutic pathway to treat inflammatory conditions by modulating the electrical signalling pattern of the autonomic connections to the spleen. However, targeting this sub-division of the...
Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves
Isha Gupta, Antonino M. Cassará, Ilya Tarotin, Matteo Donega, Jason A. Miranda, David M. Sokal, Sebastien Ouchouche, Wesley Dopson, Paul Matteucci, Esra Neufeld, Matthew A. Schiefer, Alison Rowles, Paul McGill, Justin Perkins, Nikola Dolezalova, Kourosh Saeb-Parsy, Niels Kuster, Refet Firat Yazicioglu, Jason Witherington, Daniel J. Chew
Oct 16, 2020
Abstract: Neuromodulation is a new therapeutic pathway to treat inflammatory conditions by modulating the electrical signalling pattern of the autonomic connections to the spleen. However, targeting this sub-division of the...
Quantification of clinically applicable stimulation parameters for precision near-organ neuromodulation of human splenic nerves.
Isha Gupta, Antonino M Cassará, Ilya Tarotin, Matteo Donega, Jason A Miranda, David M Sokal, Sebastien Ouchouche, Wesley Dopson, Paul Matteucci, Esra Neufeld, Matthew A Schiefer, Alison Rowles, Paul McGill, Justin Perkins, Nikola Dolezalova, Kourosh Saeb-Parsy, Niels Kuster, Refet Firat Yazicioglu, Jason Witherington, Daniel J Chew
Dec 07, 2020
Neuromodulation is a new therapeutic pathway to treat inflammatory conditions by modulating the electrical signalling pattern of the autonomic connections to the spleen. However, targeting this sub-division of the nervous system...
Spectral analysis of one-dimensional high-contrast elliptic problems with periodic coefficients
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
Spectral analysis of one-dimensional high-contrast elliptic problems with periodic coefficients
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
We study the behavior of the spectrum of a family of one-dimensional operators with periodic high-contrast coefficients as the period goes to zero, which may represent, e.g., the elastic or electromagnetic response of a...
The Relative Contribution of Executive Functions and Aging on Attentional Control During Road Crossing.
As we age, many physical, perceptual and cognitive abilities decline, which can critically impact our day-to-day lives. However, the decline of many abilities is concurrent; thus, it is challenging to disentangle the relative...
Published by: Frontiers in Psychology
Nutritional and developmental programming effects of insulin.
The discovery of insulin in 1921 was a major breakthrough in medicine and for therapy in patients with diabetes. The dramatic rise in the prevalence of overweight and obesity has been tightly linked to an increased prevalence of...
Assessment of the long-term stability of the polymer of intrinsic microporosity PIM-1 for hydrogen storage applications
Sebastien Rochat, Katarzyna Polak-Kraśna, Mi Tian, Timothy Mays, Christopher Bowen, Andrew Burrows
Jan 01, 2019
Polymers of intrinsic microporosity, such as PIM-1, advantageously combine high surface areas with good processability, which are attractive properties for hydrogen storage applications. Here we address the lack of data on the...
Hydrogen storage long-term stability physisorption Polymer of intrinsic microporosity Porous material Tensile test /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
Thermodynamics of high-pressure ice phases explored with atomistic simulations
Aleks Reinhardt, Mandy Bethkenhagen, Federica Coppari, Marius Millot, Sebastien Hamel, Bingqing Cheng
Sep 10, 2022
Most experimentally known high-pressure ice phases have a body-centred cubic (bcc) oxygen lattice. Our large-scale molecular-dynamics simulations with a machine-learning potential indicate that, amongst these bcc ice phases...
AFM imaging and nanoindentation of polymer of intrinsic microporosity PIM-1
Katarzyna Polak-Krasna, Carlos Fuhrhop, Sebastien Rochat, Andrew Burrows, Anthimos Georgiadis, Christopher Bowen, Timothy Mays
Sep 14, 2017
Polymers of intrinsic microporosity (PIMs) have promising gas adsorption properties for potential applications such as incorporation into high-pressure hydrogen storage tanks in an effort to increase the storage capacity or...
Thermodynamics of high-pressure ice phases explored with atomistic simulations
Aleks Reinhardt, Mandy Bethkenhagen, Federica Coppari, Marius Millot, Sebastien Hamel, Bingqing Cheng
Aug 11, 2022
Most experimentally known high-pressure ice phases have a body-centred cubic (bcc) oxygen lattice. Our large-scale molecular-dynamics simulations with a machine-learning potential indicate that, amongst these bcc ice phases...
Reference Genome Anchoring of High-Density Markers for Association Mapping and Genomic Prediction in European Winter Wheat.
Olufunmilayo Ladejobi, Ian J Mackay, Jesse Poland, Sebastien Praud, Julian M Hibberd, Alison R Bentley
Jan 03, 2020
In this study, we anchored genotyping-by-sequencing data to the International Wheat Genome Sequencing Consortium Reference Sequence v1.0 assembly to generate over 40,000 high quality single nucleotide polymorphism markers on a...
Solvent Sorption-Induced Actuation of Composites Based on a Polymer of Intrinsic Microporosity
Katarzyna Polak-Kraśna, Mi Tian, Sebastien Rochat, Nicholas Gathercole, Chenggang Yuan, Zhe Hao, Min Pan, Andrew Burrows, Tim Mays, Chris Bowen
Feb 12, 2021
Materials that are capable of actuation in response to a variety of external stimuli are of significant interest for applications in sensors, soft robotics, and biomedical devices. Here, we present a class of actuators using...
Assessment of the long-term stability of the polymer of intrinsic microporosity PIM-1 for hydrogen storage applications
Sebastien Rochat, Katarzyna Polak-Kraśna, Mi Tian, Timothy Mays, Christopher Bowen, Andrew Burrows
Jan 01, 2019
Polymers of intrinsic microporosity, such as PIM-1, advantageously combine high surface areas with good processability, which are attractive properties for hydrogen storage applications. Here we address the lack of data on the...
Hydrogen storage long-term stability physisorption Polymer of intrinsic microporosity Porous material Tensile test /dk/atira/pure/subjectarea/asjc/2100/2105 name=Renewable Energy, Sustainability and the Environment /dk/atira/pure/subjectarea/asjc/2100/2103 name=Fuel Technology /dk/atira/pure/subjectarea/asjc/3100/3104 name=Condensed Matter Physics /dk/atira/pure/subjectarea/asjc/2100/2102 name=Energy Engineering and Power Technology /dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energy name=SDG 7 - Affordable and Clean Energy
AFM imaging and nanoindentation of polymer of intrinsic microporosity PIM-1
Katarzyna Polak-Krasna, Carlos Fuhrhop, Sebastien Rochat, Andrew Burrows, Anthimos Georgiadis, Christopher Bowen, Timothy Mays
Sep 14, 2017
Polymers of intrinsic microporosity (PIMs) have promising gas adsorption properties for potential applications such as incorporation into high-pressure hydrogen storage tanks in an effort to increase the storage capacity or...
Nigrostriatal Dopaminergic Denervation Does Not Promote Impulsive Choice in the Rat
Robin Magnard, Yvan Vachez, Carole Carcenac, Sabrina Boulet, Jean-Luc Houeto, Marc Savasta, David Belin, Sebastien Carnicella
Jan 07, 2019
Solvent Sorption-Induced Actuation of Composites Based on a Polymer of Intrinsic Microporosity
Katarzyna Polak-Kraśna, Mi Tian, Sebastien Rochat, Nicholas Gathercole, Chenggang Yuan, Zhe Hao, Min Pan, Andrew Burrows, Tim Mays, Chris Bowen
Feb 12, 2021
Materials that are capable of actuation in response to a variety of external stimuli are of significant interest for applications in sensors, soft robotics, and biomedical devices. Here, we present a class of actuators using...
Reference Genome Anchoring of High-Density Markers for Association Mapping and Genomic Prediction in European Winter Wheat.
Olufunmilayo Ladejobi, Ian J Mackay, Jesse Poland, Sebastien Praud, Julian M Hibberd, Alison R Bentley
Jan 03, 2020
In this study, we anchored genotyping-by-sequencing data to the International Wheat Genome Sequencing Consortium Reference Sequence v1.0 assembly to generate over 40,000 high quality single nucleotide polymorphism markers on a...
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