Methyltransferases are a large class of enzymes that catalyze the transfer of methyl groups to various protein substrates. This reaction is observed in numerous cellular processes, including the regulation of gene expression...
The goal of this project was to design and synthesize small molecule inhibitors using nucleophilic substitution, reductive amination, tosylation, debenzylation, and deprotection reactions.
Fungal infections represent a global problem, notably for immunocompromised patients in hospital, COVID-19 patient wards and care home settings, and the ever-increasing emergence of multidrug resistant fungal strains is a sword...
BACKGROUND: Selecting optimal stimulation parameters from numerous possibilities is a major obstacle for assessing the efficacy of non-invasive brain stimulation. OBJECTIVE: We demonstrate that Bayesian optimization can rapidly...
BACKGROUND: Heterodera glycines, commonly referred to as the soybean cyst nematode (SCN), is an obligatory and sedentary plant parasite that causes over a billion-dollar yield loss to soybean production annually. Although there...
$\textbf{BACKGROUND & PURPOSE}$: Increasing our appreciation of the historical foundations of hip arthroscopy offers greater insight and understanding of the field's current and future applications. This article offers a broad...
America. No Longer the Beautiful September 11, 2002: A Changed Nation Remembers Omwake Party Closed for Overcrowding The Dangers of Limerick: KI Pills Soon The Freshman Fifteen: A Preventable Phenomenon for Students ...
BACKGROUND: The Vibrant Soundbridge middle ear implant and the Bonebridge bone conducting hearing device are hearing implants that use radio frequency transmission to send information from the sound processor to the internal...