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Results: 2309
When males live longer
Chi-Ying Lee, David A Pike, Hui-Yun Tseng, Jung-Ya Hsu, Shiang-Lin Huang, Pei-Jen L Shaner, Chen-Pan Liao, Andrea Manica, Wen-San Huang
Jun 20, 2019
Phylogenetic analysis has shown that males' propensity to engage in aggressive encounters is associated with females having greater longevity. Here, we confirm the causal link between aggression and reduced longevity by looking...
Scholarship Endowment Commemorates Late Alumna Lin Fearrington Thomas '81, '83
Winthrop University
Jan 01, 0001
Recent endowment has made the Lin Fearrington Thomas Scholarship a permanent fund at Winthrop. Thomas earned B.A. and M.B.A. degrees as a post-traditional student in the 1980s.
Published by: Winthrop University
DREAM represses distinct targets by cooperating with different THAP domain proteins.
Csenge Gal, Francesco Nicola Carelli, Alex Appert, Chiara Cerrato, Ni Huang, Yan Dong, Jane Murphy, Andrea Frapporti, Julie Ahringer
Sep 27, 2021
The DREAM (dimerization partner [DP], retinoblastoma [Rb]-like, E2F, and MuvB) complex controls cellular quiescence by repressing cell-cycle and other genes, but its mechanism of action is unclear. Here, we demonstrate that two...
dream H2A.Z H3K9me2 THAP lin-15B lin-35 lin-36 quiescence retinoblastoma TRANSCRIPTIONAL REPRESSION Animals Animals Genetically Modified Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Proteins DNA Methylation E2F Transcription Factors Gene Expression Regulation Histones Promoter Regions Genetic Protein Binding Protein Interaction Domains and Motifs Retinoblastoma Protein Transcription Factors
A novel deep intronic variant strongly associates with Alkaptonuria.
Chien-Yi Lai, I-Jung Tsai, Pao-Chin Chiu, David B Ascher, Yin-Hsiu Chien, Yu-Hsuan Huang, Yi-Lin Lin, Wuh-Liang Hwu, Ni-Chung Lee
Oct 22, 2021
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
A novel deep intronic variant strongly associates with Alkaptonuria.
Chien-Yi Lai, I-Jung Tsai, Pao-Chin Chiu, David B Ascher, Yin-Hsiu Chien, Yu-Hsuan Huang, Yi-Lin Lin, Wuh-Liang Hwu, Ni-Chung Lee
Jan 06, 2022
Alkaptonuria is a rare autosomal recessive inherited disorder of tyrosine metabolism, which causes ochronosis, arthropathy, cardiac valvular calcification, and urolithiasis. The epidemiology of alkaptonuria in East Asia is not...
Update on antiarrhythmic drug pharmacology.
Cardiac arrhythmias constitute a major public health problem. Pharmacological intervention remains mainstay to their clinical management. This, in turn, depends upon systematic drug classification schemes relating their...
Modernized Oxford Classification Vaughan-Williams antiarrhythmic drugs cardiac arrhythmias sicilian gambit Action Potentials Animals Anti-Arrhythmia Agents Arrhythmias Cardiac Heart Conduction System Heart Rate Humans Molecular Targeted Therapy Myocardial Contraction Treatment Outcome Ventricular Function Ventricular Remodeling
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.
Alicia N McMurchy, Przemyslaw Stempor, Tessa Gaarenstroom, Brian Wysolmerski, Yan Dong, Darya Aussianikava, Alex Appert, Ni Huang, Paulina Kolasinska-Zwierz, Alexandra Sapetschnig, Eric A Miska, Julie Ahringer
Aug 17, 2017
Repetitive sequences derived from transposons make up a large fraction of eukaryotic genomes and must be silenced to protect genome integrity. Repetitive elements are often found in heterochromatin; however, the roles and...
C. elegans DNA Damage Chromosomes evolutionary biology Genes Genomics Germ line Heterochromatin nuclear RNAi piRNA repetitive elements Animals Apoptosis Caenorhabditis elegans Caenorhabditis elegans Proteins Chromosomal Proteins Non-Histone DNA Repair Gene Expression Regulation Germ Cells Heterochromatin Interspersed Repetitive Sequences RNA Interference RNA Small Interfering
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
On the direct insulator-quantum Hall transition in two-dimensional electron systems in the vicinity of nanoscaled scatterers.
Fast decoupled state estimation for distribution networks considering branch ampere measurements
Fast decoupled state estimation (FDSE) is proposed for distribution networks, with fast convergence and high efficiency. Conventionally, branch current magnitude measurements cannot be incorporated into FDSE models; however, in...
A protein complex required for polar growth of rhizobial infection threads
Cheng-Wu Liu, Andrew Breakspear, Nicola Stacey, Kim Findlay, Jin Nakashima, Karunakaran Ramakrishnan, Miaoxia Liu, Fang Xie, Gabriella Endre, Fernanda de Carvalho-Niebel, Giles E. D. Oldroyd, Michael K. Udvardi, Joëlle Fournier, Jeremy D. Murray
Jun 27, 2020
Abstract: During root nodule symbiosis, intracellular accommodation of rhizobia by legumes is a prerequisite for nitrogen fixation. For many legumes, rhizobial colonization initiates in root hairs through transcellular infection...
Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development.
Andrew C Lin, Chin Lik Tan, Chien-Ling Lin, Laure Strochlic, Yi-Shuian Huang, Joel D Richter, Christine E Holt
Jun 16, 2011
Animals Axons Base Sequence Cytoplasm Fluorescent Antibody Technique Gene Expression Regulation In Situ Hybridization Molecular Sequence Data Plasmids Polyadenylation Protein Biosynthesis RNA Messenger Retinal Ganglion Cells Reverse Transcriptase Polymerase Chain Reaction Transcription Factors Xenopus Xenopus Proteins mRNA Cleavage and Polyadenylation Factors
Improving Timeliness in the Neglected Tropical Diseases Preventive Chemotherapy Donation Supply Chain through Information Sharing
Background
Billions of doses of medicines are donated for mass drug administrations in support of the World Health Organization’s “Roadmap to Implementation,” which aims to control, eliminate, and eradicate Neglected...
Billions of doses of medicines are donated for mass drug administrations in support of the World Health Organization’s “Roadmap to Implementation,” which aims to control, eliminate, and eradicate Neglected...
Components of AR-quivers for string algebras of type C˜ and a conjecture by Geiss-Leclerc-Schröer
We study modules of certain string algebras, which are referred to as of affine type C˜. We introduce minimal string modules and apply them to explicitly describe components of the Auslander-Reiten quivers of the string...
Improving Timeliness in the Neglected Tropical Diseases Preventive Chemotherapy Donation Supply Chain through Information Sharing
Background
Billions of doses of medicines are donated for mass drug administrations in support of the World Health Organization’s “Roadmap to Implementation,” which aims to control, eliminate, and eradicate Neglected...
Billions of doses of medicines are donated for mass drug administrations in support of the World Health Organization’s “Roadmap to Implementation,” which aims to control, eliminate, and eradicate Neglected...
Ultrahigh energy storage in superparaelectric relaxor ferroelectrics.
Hao Pan, Shun Lan, Shiqi Xu, Qinghua Zhang, Hongbao Yao, Yiqian Liu, Fanqi Meng, Er-Jia Guo, Lin Gu, Di Yi, Xiao Renshaw Wang, Houbing Huang, Judith L Macmanus-Driscoll, Long-Qing Chen, Kui-Juan Jin, Ce-Wen Nan, Yuan-Hua Lin
Oct 06, 2021
Electrostatic energy storage technology based on dielectrics is fundamental to advanced electronics and high-power electrical systems. Recently, relaxor ferroelectrics characterized by nanodomains have shown great promise as...
In Materia Neuron Spiking Plasticity for Sequential Event Processing Based on Dual-Mode Memristor
Linbo Shan, Zongwei Wang, Lin Bao, Shengyu Bao, Yabo Qin, Yaotian Ling, Guandong Bai, John Robertson, Yimao Cai, Ru Huang
Mar 09, 2022
Artificial neurons are the fundamental elements in neuromorphic computing systems. Studies have revealed neuronal spike‐rate adaptation owing to intrinsic plasticity that neurons will adapt to the spiking patterns and store the...
Motivation Model for Rural Teachers in China to Continuously Embrace Digital Teaching Models
Rural teachers are responsible for effectively implementing and continuously developing digital teaching models in rural areas in the rapidly digitizing society. This study investigated the motivational factors influencing rural...
Published by: IGI Global Scientific Publishing
Components of AR-quivers for string algebras of type C˜ and a conjecture by Geiss-Leclerc-Schröer
We study modules of certain string algebras, which are referred to as of affine type C˜. We introduce minimal string modules and apply them to explicitly describe components of the Auslander-Reiten quivers of the string...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
Apr 02, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion.
Ting Deng, Przemyslaw Stempor, Alex Appert, Michael Daube, Julie Ahringer, Alex Hajnal, Evelyn Lattmann
May 15, 2020
Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in...
Animals Basement Membrane Caenorhabditis elegans Caenorhabditis elegans Proteins Cell Cycle Checkpoints Cell Differentiation Cell Proliferation G1 Phase Cell Cycle Checkpoints Gene Expression MDS1 and EVI1 Complex Locus Protein Proto-Oncogene Mas Proto-Oncogene Proteins c-fos Proto-Oncogenes Receptors Notch Signal Transduction Transcription Factors
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