Search
Results: 3187
Letter to Dr. Simon Flexner, 1929
Library Staff
Jan 01, 0001
Letter to Dr. Simon Flexner, 1929
Published by: Library
Letter to Simon Flexner, 1933
Markus Library
Jan 01, 0001
Letter to Simon Flexner from William Snow, General Director of the American Social Hygiene Association, July 12th, 1933
Published by: Rockefeller University
Simon Flexner, 1911
The Rockefeller University
Jan 01, 0001
Simon Flexner, M.D. Local specific Therapy of Infections
Delivered October 7th, 1911
Published by: J.B. Lippincott Company
Selecting Rotation Constants on SIMON-Type Ciphers
In 2013, a lightweight block cipher SIMON is proposed by NSA. This paper tries to investigate this design criterion in terms of resisting against impossible differential cryptanalysis. On one hand, starting from all the possible...
Published by: IGI Global Scientific Publishing
Mouse models of colorectal cancer as preclinical models.
Itraconazole perturbs colorectal cancer dormancy through SUFU-mediated WNT inhibition.
Cancer cell dormancy is an important source of treatment failure. We studied the molecular characteristics and functional behaviour of dormant colorectal cancer cells finding them to be a differentiated yet plastic population....
5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation.
Santiago Uribe-Lewis, Thomas Carroll, Suraj Menon, Anna Nicholson, Piotr J Manasterski, Douglas J Winton, Simon J A Buczacki, Adele Murrell
Feb 19, 2020
Cytosine hydroxymethylation (5hmC) in mammalian DNA is the product of oxidation of methylated cytosines (5mC) by Ten-Eleven-Translocation (TET) enzymes. While it has been shown that the TETs influence 5mC metabolism...
Published by: Scientific reports
An analysis of SARS-CoV-2 cell entry genes identifies the intestine and colorectal cancer as susceptible tissues.
Mahnaz Darvish-Damavandi, James Laycock, Christopher Ward, Milou S van Driel, Mae A Goldgraben, Simon JA Buczacki
Jun 23, 2020
5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation
Santiago Uribe-Lewis, Thomas Carroll, Suraj Menon, Anna Nicholson, Piotr J. Manasterski, Douglas J. Winton, Simon J. A. Buczacki, Adele Murrell
Jan 16, 2021
Abstract: Cytosine hydroxymethylation (5hmC) in mammalian DNA is the product of oxidation of methylated cytosines (5mC) by Ten-Eleven-Translocation (TET) enzymes. While it has been shown that the TETs influence 5mC metabolism...
Itraconazole targets cell cycle heterogeneity in colorectal cancer.
Simon JA Buczacki, Semiramis Popova, Emma Biggs, Chrysa Koukorava, Jon Buzzelli, Louis Vermeulen, Lee Hazelwood, Hayley Francies, Mathew J Garnett, Douglas J Winton
Sep 05, 2018
Cellular dormancy and heterogeneity in cell cycle length provide important explanations for treatment failure after adjuvant therapy with S-phase cytotoxics in colorectal cancer (CRC), yet the molecular control of the dormant...
Animals Cell Cycle Cell Cycle Checkpoints Cell Differentiation Cell Line Tumor Cell Proliferation Cell Separation Cellular Senescence Colorectal Neoplasms Humans Itraconazole Mice Neoplastic Stem Cells Organoids Phenotype Receptors G-Protein-Coupled Spheroids Cellular Staining and Labeling Wnt Signaling Pathway
Adenomas as a risk factor in familial colorectal cancer
Adenoma Adenomatous Polyposis Coli Carcinoma Colonic Polyps Colonoscopy Colorectal Neoplasms Colorectal Neoplasms Hereditary Nonpolyposis Databases Factual Early Detection of Cancer Genetic Predisposition to Disease Health Care Costs Humans Medical History Taking Models Theoretical Pedigree Practice Guidelines as Topic Risk Assessment State Medicine United Kingdom
Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer.
Rachael E Clifford, Naren Govindarajah, David Bowden, Paul Sutton, Mark Glenn, Mahnaz Darvish-Damavandi, Simon Buczacki, Ultan McDermott, Zdzislaw Szulc, Besim Ogretmen, Jason L Parsons, Dale Vimalachandran
Jan 05, 2021
Previous work utilizing proteomic and immunohistochemical analyses has identified that high levels of acid ceramidase (AC) expression confers a poorer response to neoadjuvant treatment in locally advanced rectal cancer. We aimed...
Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer
Rachael E. Clifford, Naren Govindarajah, David Bowden, Paul Sutton, Mark Glenn, Mahnaz Darvish-Damavandi, Simon Buczacki, Ultan McDermott, Zdzislaw Szulc, Besim Ogretmen, Jason L. Parsons, Dale Vimalachandran
Dec 22, 2020
Previous work utilizing proteomic and immunohistochemical analyses has identified that high levels of acid ceramidase (AC) expression confers a poorer response to neoadjuvant treatment in locally advanced rectal cancer. We aimed...
Isolation of Human Colon Stem Cells Using Surface Expression of PTK7.
Peter Jung, Christian Sommer, Francisco M Barriga, Simon J Buczacki, Xavier Hernando-Momblona, Marta Sevillano, Miquel Duran-Frigola, Patrick Aloy, Matthias Selbach, Douglas J Winton, Eduard Batlle
Sep 05, 2018
Insertion of reporter cassettes into the Lgr5 locus has enabled the characterization of mouse intestinal stem cells (ISCs). However, low cell surface abundance of LGR5 protein and lack of high-affinity anti-LGR5 antibodies...
The Grizzly, November 17, 2011
Liz Kilmer, Nick Pane, Jenna Yaich, Lisa Jobe, Ron Stranix, Eva Bramesco, Julia Fox, Sarah Bollert, Marina McCann, Anna Larouche, Dave Muoio, Hilary Gibbs, Shane Eachus, James Noebels, Dixon Speaker
Jan 01, 0001
Professor Named "Huffington Post" Contributor November Focuses on Sophomores UCDC Offers Multiple Performances This Week Bearitones, B'Nats Premiere "Let's Du Et!?" Students Compete at Simon Business School Senior Interns...
Ursinus College Collegeville Pennsylvania newspaper Domenick Scudera Missy Bryant dance Bearitones B'Naturals Business and Economics Department Mike Ward Kirstie Hettinga track team Football Greg Martell Bill Racich wrestling field hockey cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Introduction to the special issue on existence theory
After exploring the main tenets of existence theory and the affinities between this theory and other philosophical traditions, this introduction lists the central points of each contribution to this special issue. In...
Dissecting Mammalian Replication-Independent Chromatin Assembly â" Biochemical and Structural Studies on the H3.3-Specific Histone Chaperones Hira and Daxx
Simon Elsässer
Jan 01, 0001
Histones are architectural proteins that wrap approximately two turns of DNA around their octameric core structure, constituting the fundamental packaging unit of eukaryotic chromatin â" the nucleosome. Beyond their structural...
histone H3 variants H3.3 Histone Chaperones Chromatin Daxx protein ATRX (ATP-dependent chromatin remodeler Life Sciences
Published by: Rockefeller University
APOBEC mutagenesis is a common process in normal human small intestine.
Yichen Wang, Philip S Robinson, Tim HH Coorens, Luiza Moore, Henry Lee-Six, Ayesha Noorani, Mathijs A Sanders, Hyunchul Jung, Riku Katainen, Robert Heuschkel, Roxanne Brunton-Sim, Robyn Weston, Debbie Read, Beverley Nobbs, Rebecca C Fitzgerald, Kourosh Saeb-Parsy, Iñigo Martincorena, Peter J Campbell, Simon Rushbrook, Matthias Zilbauer, Simon James Alexander Buczacki, Michael R Stratton
Feb 16, 2023
Dr. Flexner's Experiment: [Dr. Simon Flexner]
M. S. Kaplan
Jan 01, 0001
Rockefeller University Research Profiles are a series of scientific profiles that were published quarterly, from 1980-1990, by the Rockefeller University. Each issue features the research and achievements of an individual...
Flexner Simon Rockefeller University Scientists Rockefeller University history Rockefeller Institute for Medical Research Carrel Alexis Meltzer Samuel Noguchi Hideyo Life Sciences
Published by: The Rockefeller University
MIRSKY HOLIDAY LECTURES ON SCIENCE 2008
The Rockefeller University
Jan 01, 0001
49th Annual Alfred E. Mirsky Holiday Lecture on Science for high school students Five Life, through a Lens: What You Can Learn about Biology Simply by Looking delivered by Sanford Simon
Published by: The Rockefeller University
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.
Philip S Robinson, Laura E Thomas, Federico Abascal, Hyunchul Jung, Luke MR Harvey, Hannah D West, Sigurgeir Olafsson, Bernard CH Lee, Tim HH Coorens, Henry Lee-Six, Laura Butlin, Nicola Lander, Rebekah Truscott, Mathijs A Sanders, Stefanie V Lensing, Simon JA Buczacki, Rogier Ten Hoopen, Nicholas Coleman, Roxanne Brunton-Sim, Simon Rushbrook, Kourosh Saeb-Parsy, Fiona Lalloo, Peter J Campbell, Iñigo Martincorena, Julian R Sampson, Michael R Stratton
Aug 08, 2022
Cellular DNA damage caused by reactive oxygen species is repaired by the base excision repair (BER) pathway which includes the DNA glycosylase MUTYH. Inherited biallelic MUTYH mutations cause predisposition to colorectal...
APOBEC mutagenesis is a common process in normal human small intestine.
Yichen Wang, Philip S Robinson, Tim HH Coorens, Luiza Moore, Henry Lee-Six, Ayesha Noorani, Mathijs A Sanders, Hyunchul Jung, Riku Katainen, Robert Heuschkel, Roxanne Brunton-Sim, Robyn Weston, Debbie Read, Beverley Nobbs, Rebecca C Fitzgerald, Kourosh Saeb-Parsy, Iñigo Martincorena, Peter J Campbell, Simon Rushbrook, Matthias Zilbauer, Simon James Alexander Buczacki, Michael R Stratton
Feb 26, 2023
APOBEC mutational signatures SBS2 and SBS13 are common in many human cancer types. However, there is an incomplete understanding of its stimulus, when it occurs in the progression from normal to cancer cell and the APOBEC...
The use of oral antibiotics and mechanical bowel preparation in elective colorectal resection for the reduction of surgical site infection.
SE Duff, CLF Battersby, RJ Davies, L Hancock, J Pipe, S Buczacki, J Kinross, AG Acheson, CJ Walsh
Jan 09, 2020
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.
Philip S Robinson, Laura E Thomas, Federico Abascal, Hyunchul Jung, Luke MR Harvey, Hannah D West, Sigurgeir Olafsson, Bernard CH Lee, Tim HH Coorens, Henry Lee-Six, Laura Butlin, Nicola Lander, Rebekah Truscott, Mathijs A Sanders, Stefanie V Lensing, Simon JA Buczacki, Rogier Ten Hoopen, Nicholas Coleman, Roxanne Brunton-Sim, Simon Rushbrook, Kourosh Saeb-Parsy, Fiona Lalloo, Peter J Campbell, Iñigo Martincorena, Julian R Sampson, Michael R Stratton
Jul 08, 2022
Cellular DNA damage caused by reactive oxygen species is repaired by the base excision repair (BER) pathway which includes the DNA glycosylase MUTYH. Inherited biallelic MUTYH mutations cause predisposition to colorectal...
|
|< |
< |
1 |