Search
Results: 22398
Letter to Dr. Simon Flexner, 1929
Library Staff
Jan 01, 0001
Letter to Dr. Simon Flexner, 1929
Published by: Library
Letter to Simon Flexner, 1933
Markus Library
Jan 01, 0001
Letter to Simon Flexner from William Snow, General Director of the American Social Hygiene Association, July 12th, 1933
Published by: Rockefeller University
Simon Flexner, 1911
The Rockefeller University
Jan 01, 0001
Simon Flexner, M.D. Local specific Therapy of Infections
Delivered October 7th, 1911
Published by: J.B. Lippincott Company
Selecting Rotation Constants on SIMON-Type Ciphers
In 2013, a lightweight block cipher SIMON is proposed by NSA. This paper tries to investigate this design criterion in terms of resisting against impossible differential cryptanalysis. On one hand, starting from all the possible...
Published by: IGI Global Scientific Publishing
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Dec 19, 2019
The eukaryotic translation initiation factor 2α (eIF2α) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as...
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells.
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Jan 03, 2020
The eukaryotic translation initiation factor 2a (eIF2a) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as...
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells.
Heather P Harding, Adriana Ordonez, Felicity Allen, Leopold Parts, Alison J Inglis, Roger L Williams, David Ron
Nov 21, 2019
CHO GCN2 P-stalk Cell Biology Genetics Genomics integrated stress response p1 p2 ribosome stalling ul10 Amino Acids Animals CHO Cells CRISPR-Cas Systems Cricetulus Endoplasmic Reticulum Gene Expression Regulation Enzymologic HeLa Cells Humans Kinetics Ligands Mice Models Molecular Mutagenesis Phosphorylation Protein Binding Protein Conformation Protein Serine-Threonine Kinases Protein Unfolding RNA Transfer Ribosomes Signal Transduction Starvation Transcriptome eIF-2 Kinase
Interview with Gwen P. Howell
Gwen P. Howell
Jan 01, 0001
Interview with Gwen P. Howell, member of the South Carolina Mothers Association.
Published by: Winthrop University
Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Many regulatory PPP1R subunits join few catalytic PP1c subunits to mediate phosphoserine and phosphothreonine dephosphorylation in metazoans. Regulatory subunits engage the surface of PP1c, locally affecting flexible access of...
Published by: Nature structural & molecular biology
Higher-order phosphatase-substrate contacts terminate the integrated stress response.
Higher-order phosphatase–substrate contacts terminate the integrated stress response
Abstract: Many regulatory PPP1R subunits join few catalytic PP1c subunits to mediate phosphoserine and phosphothreonine dephosphorylation in metazoans. Regulatory subunits engage the surface of PP1c, locally affecting flexible...
PSK Method for Solving Mixed and Type-4 Intuitionistic Fuzzy Solid Transportation Problems
P. Kumar
Apr 01, 2019
In this article, the author categorises the solid transportation problem (STP) under uncertain environments. He formulates the mixed and fully intuitionistic fuzzy solid transportation problems (FIFSTPs) and utilizes the...
Published by: IGI Global Scientific Publishing
Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers.
Circulating polymers of α1-antitrypsin (α1AT) are neutrophil chemo-attractants and contribute to inflammation, yet cellular factors affecting their secretion remain obscure. We report on a genome-wide CRISPR-Cas9 screen for...
A rational roadmap for SARS-CoV-2/COVID-19 pharmacotherapeutic research and development
Steve PH Alexander, Jane F Armstrong, Anthony P Davenport, Jamie A Davies, Elena Faccenda, Simon D Harding, Francesca Levi-Schaffer, Janet J Maguire, Adam J Pawson, Christopher Southan, Michael Spedding
Apr 29, 2020
A spine approach to branching diffusions with applications to L-p-convergence of martingales
We present a modified formalization of the 'spine' change of measure approach for branching diffusions in the spirit, of those found in Kyprianou [40] and Lyons et al. [44, 437 41]. We use our formulation to interpret certain...
A spine approach to branching diffusions with applications to L-p-convergence of martingales
We present a modified formalization of the 'spine' change of measure approach for branching diffusions in the spirit, of those found in Kyprianou [40] and Lyons et al. [44, 437 41]. We use our formulation to interpret certain...
Evaluating the Impact of a SNAP Challenge on University Participant Attitudes Toward Poverty
Susan Tyler Wallace Harding
Jan 01, 0001
Objective: The purpose of this study was to evaluate whether a week-long SNAP Challenge completed by university participants influenced perceptions about poverty. Design: Pretest and posttest questionnaires measured changes in...
Published by: Winthrop University
On <em>p</em>-values for smooth components of an extended generalized additive model
Simon N Wood
Mar 01, 2013
The problem of testing smooth components of an extended generalized additive model for equality to zero is considered. Confidence intervals for such components exhibit good across-the-function coverage probabilities if based on...
On <em>p</em>-values for smooth components of an extended generalized additive model
Simon N Wood
Mar 01, 2013
The problem of testing smooth components of an extended generalized additive model for equality to zero is considered. Confidence intervals for such components exhibit good across-the-function coverage probabilities if based on...
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20
Stephen Ph Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators
Dec 12, 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective...
Relationships between selective neuronal loss and microglial activation after ischaemic stroke in man.
Rhiannon S Morris, P Simon Jones, Josef A Alawneh, Young T Hong, Tim D Fryer, Franklin I Aigbirhio, Elizabeth A Warburton, Jean-Claude Baron
Nov 06, 2018
Modern ischaemic stroke management involves intravenous thrombolysis followed by mechanical thrombectomy, which allows markedly higher rates of recanalization and penumbral salvage than thrombolysis alone. However, <50% of...
Piloting a digitally-mediated social story intervention for autistic children led by teachers within naturalistic school settings
Elizabeth Smith, P. Toms, Aurora Constantin, Hilary Johnson, Elissa Harding, Mark Brosnan
Jul 01, 2020
Background
Social stories (SS) are widely used within the autism community. However, research into their effectiveness is mixed at best and mainly relies on single case study designs. Additional support from the researcher...
Social stories (SS) are widely used within the autism community. However, research into their effectiveness is mixed at best and mainly relies on single case study designs. Additional support from the researcher...
Adaptable P body physical states differentially regulate bicoid mRNA storage during early Drosophila development.
M Sankaranarayanan, Ryan J Emenecker, Elise L Wilby, Marcus Jahnel, Irmela REA Trussina, Matthew Wayland, Simon Alberti, Alex S Holehouse, Timothy Weil
Nov 22, 2021
Ribonucleoprotein condensates can exhibit diverse physical states in vitro and in vivo. Despite considerable progress, the relevance of condensate physical states for in vivo biological function remains limited. Here, we...
|
|< |
< |
1 |