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Results: 5153
Cell type-specific YAP1-WWTR1/TAZ transcriptional responses after autophagy perturbations are determined by levels of α-catenins (CTNNA1 and CTNNA3).
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
Sung Min Son, So Jung Park, Eleanna Stamatakou, Mariella Vicinanza, Fiona M. Menzies, David C. Rubinsztein
Jun 19, 2021
Leucine regulates autophagy via acetylation of the mTORC1 component raptor.
Sung Min Son, So Jung Park, Eleanna Stamatakou, Mariella Vicinanza, Fiona M Menzies, David C Rubinsztein
May 28, 2020
Macroautophagy ("autophagy") is the main lysosomal catabolic process that becomes activated under nutrient-depleted conditions, like amino acid (AA) starvation. The mechanistic target of rapamycin complex 1 (mTORC1) is a...
Vinexin contributes to autophagic decline in brain ageing across species.
So Jung Park, Rebecca A Frake, Cansu Karabiyik, Sung Min Son, Farah H Siddiqi, Carla F Bento, Peter Sterk, Mariella Vicinanza, Mariana Pavel, David C Rubinsztein
May 10, 2022
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
Sung Min Son, So Jung Park, Eleanna Stamatakou, Mariella Vicinanza, Fiona M. Menzies, David C. Rubinsztein
Jun 19, 2020
Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A.
Sung Min Son, So Jung Park, Huikyong Lee, Farah Siddiqi, Jong Eun Lee, Fiona M Menzies, David C Rubinsztein
Sep 21, 2018
The mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) is a master regulator of cell growth and metabolism. Leucine (Leu) activates mTORC1 and many have tried to identify the mechanisms whereby cells sense Leu in this...
English Professor Explores Jung, Africa in New Text
Winthrop University
Jan 01, 0001
Fike joined the Winthrop community in 2000 and teaches courses on Shakespeare and Renaissance literature. Past publications include three critical books: "Spenser's Underworld in the 1590 'Faerie Queen'"; "A Jungian Study of...
Published by: Winthrop University
Hunting and Consumption of Passerine Birds by Wild Mallards (Anas platyrhynchos)
Predation of vertebrates by Mallards ($\textit{Anas platyrhynchos}$) has rarely been documented and only in relation to fish and amphibians. Mallard foraging behavior was observed at a reservoir bordering Semenic-Caras Gorges...
Spanish Park Trip Inspires Latest Composition Piece
Winthrop University
Jan 01, 0001
Premiere dates for "Park Guell" are Jan. 26 and Jan. 31 in Charlotte. More information can be found online at ronparksmusic.com.
Published by: Winthrop University
Parkaeology and climate change
Caitlin Rankin, Christy Mog, Shawn Jones, , J. Eva Meharry, , Rebecca Haboucha, , Margaret Comer, National Park Service
May 30, 2018
The United States National Park Service (NPS) recognizes that cultural resources are particularly vulnerable to climate change impacts because such resources are fixed on the landscape, cannot be replaced, and, if lost, lost...
Faculty Members' Documentary Details Spartanburg's Duncan Park Stadium
Winthrop University
Jan 01, 0001
"Duncan Park Stadium: 85 Years of Baseball Memories" will air Oct. 20 and Oct. 24 on ETV. Faculty members Mark Nortz and Albert Bolognese started working on the documentary in January 2010.
Published by: Winthrop University
Mendelian neurodegenerative disease genes involved in autophagy.
Eleanna Stamatakou, Lidia Wróbel, Sandra Malmgren Hill, Claudia Puri, Sung Min Son, Motoki Fujimaki, Ye Zhu, Farah Siddiqi, Marian Fernandez-Estevez, Marco M Manni, So Jung Park, Julien Villeneuve, David Chaim Rubinsztein
Mar 12, 2020
The lysosomal degradation pathway of macroautophagy (herein referred to as autophagy) plays a crucial role in cellular physiology by regulating the removal of unwanted cargoes such as protein aggregates and damaged organelles....
Improving Park Maintenance Efficiency Using a Mobile Application
This article describes the construction and evaluation of a mobile application for use by park maintenance personnel that features an interactive map allowing for real time positioning of the user in relation to equipment...
Published by: IGI Global Scientific Publishing
Winthrop Board Displays Unanimous Support of Knowledge Park Initiative
Winthrop University
Jan 01, 0001
Trustees unanimously approved a resolution to endorse the Knowledge Park initiative during the June 19 quarterly meeting. The Knowledge Park concept was developed in 2012 as public and private leaders joined together to...
Published by: Winthrop University
Heterogeneous nuclear ribonucleoprotein A1 post-transcriptionally regulates Drp1 expression in neuroblastoma cells.
So Jung Park, Heejin Lee, Doo Shin Jo, Yoon Kyung Jo, Ji Hyun Shin, Han Byeol Kim, Hae Mi Seo, David C Rubinsztein, Jae-Young Koh, Eun Kyung Lee, Dong-Hyung Cho
Oct 27, 2015
Drp1 Mitochondria dynamics RNA binding protein hnRNP A1 3' Untranslated Regions Cell Line Tumor Cell Nucleus Cytoplasm Dynamins GTP Phosphohydrolases Gene Expression Regulation Neoplastic Heterogeneous Nuclear Ribonucleoprotein A1 Heterogeneous-Nuclear Ribonucleoprotein Group A-B Humans Microtubule-Associated Proteins Mitochondrial Dynamics Mitochondrial Proteins Neoplasm Proteins Neuroblastoma Protein Binding Protein Transport RNA processing Post-Transcriptional RNA Messenger RNA Neoplasm
Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis.
Mariana Pavel, Maurizio Renna, So Jung Park, Fiona M Menzies, Thomas Ricketts, Jens Füllgrabe, Avraham Ashkenazi, Rebecca A Frake, Alejandro Carnicer Lombarte, Carla F Bento, Kristian Franze, David C Rubinsztein
Sep 08, 2018
Actin Cytoskeleton Actins Acyltransferases Adaptor Proteins Signal Transducing Animals Apoptosis Autophagosomes Autophagy CapZ Actin Capping Protein Cell Count Cell Line Tumor Cell Proliferation Cell Survival Contact Inhibition Epithelial Cells Extracellular Matrix FIBROBLASTS Gene Knockdown Techniques Glucose HeLa Cells Humans Hypoxia Mice Myosin Type II Phosphoproteins Signal Transduction Transcription Factors YAP-Signaling Proteins
Optimal PM2.5 emission reduction strategies for an industrial park based on China’s 12th five-year plan on air pollution prevention and control
Over the past decades, China has been undertaking extremely rapid industrialization and urbanization. Along with economic boom, many adverse environmental effects are emerging. Among them, it is of great significance for the...
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