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Corticocortical and Thalamocortical Changes in Functional Connectivity and White Matter Structural Integrity after Reward-Guided Learning of Visuospatial Discriminations in Rhesus Monkeys.
Vassilis Pelekanos, Elsie Premereur, Daniel J Mitchell, Subhojit Chakraborty, Stuart Mason, Andy CH Lee, Anna S Mitchell
Dec 08, 2020
The frontal cortex and temporal lobes together regulate complex learning and memory capabilities. Here, we collected resting-state functional and diffusion-weighted MRI data before and after male rhesus macaque monkeys received...
cingulate cortex learning mediodorsal thalamus orbitofrontal cortex Reward uncinate fasciculus Animals Brain Mapping Cerebral Cortex Conditioning Operant discrimination Psychological Fornix Brain Macaca mulatta Magnetic Resonance Imaging Male Memory Neural Pathways Reward Space Perception Thalamus Visual Perception white matter
A systematic review
Anupam Datta Gupta, Wing Hong Chu, Stuart Howell, Subhojit Chakraborty, Simon Koblar, Renuka Visvanathan, Ian Cameron, David Wilson
May 25, 2018
BACKGROUND: Improved walking is one of the highest priorities in people living with stroke. Post-stroke lower limb spasticity (PSLLS) impedes walking and quality of life (QOL). The understanding of the evidence of improved...
Investigation of CD26, a potential SARS-CoV-2 receptor, as a biomarker of age and pathology.
Animesh Alexander Raha, Subhojit Chakraborty, James Henderson, Elizabeta Mukaetova-Ladinska, Shahid Zaman, John Trowsdale, Ruma Raha-Chowdhury
Feb 05, 2021
OBJECTIVE: In some individuals, coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leads to a variety of serious inflammatory symptoms, including blood clotting and acute respiratory distress....
Corona virus COVID-19 Covid-19 biomarker SARS-CoV-2 infection type 2 diabetes mellitus age-related dementia dipeptidyl peptidase 4 (DPP4) Adult Age Factors Aged Aged 80 and over Animals Biomarkers covid-19 Comorbidity Dementia Diabetes mellitus Type 2 Dipeptidyl Peptidase 4 Duodenum Gene Expression Host-Pathogen Interactions Humans Mice Inbred C57BL Middle Aged SARS-CoV-2
Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain
Animesh Alexander Raha, Anwesha Biswas, James Henderson, Subhojit Chakraborty, Anthony Holland, Robert P Friedland, Elizabeta Mukaetova-Ladinska, Shahid Zaman, Ruma Raha-Chowdhury
Mar 18, 2022
Iron accumulates in the ageing brain and in brains with neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and Down syndrome (DS) dementia. However, the mechanisms...
Alzheimer’s disease (AD) Down syndrome (DS) Parkinson’s disease (PD) basal ganglia ferritin Hepcidin Locus Coeruleus neurodegeneration Substantia Nigra Alzheimer Disease Brain Cation Transport Proteins Down Syndrome Ferritins Hepcidins Humans Iron Neurodegenerative Diseases Parkinson Disease Protein Aggregates
Hepcidin Increases Cytokines in Alzheimer’s Disease and Down’s Syndrome Dementia
Animesh Alexander Raha, Seyedeh Deniz Ghaffari, James Henderson, Subhojit Chakraborty, Kieren Allinson, Robert P. Friedland, Anthony Holland, Shahid H. Zaman, Elizabeta B. Mukaetova-Ladinska, Ruma Raha-Chowdhury
May 20, 2021
The liver-derived hormone hepcidin, a member of the defensin family of antimicrobial peptides, plays an important role in host defense and innate immunity due to its broad antibacterial and antiviral properties. Ferritin, an...
Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia.
Ruma Raha-Chowdhury, Animesh Alexander Raha, James Henderson, Seyedeh Deniz Ghaffari, Monika Grigorova, Jessica Beresford-Webb, Kieren Allinson, Subhojit Chakraborty, Anthony Holland, Shahid H Zaman
Aug 02, 2021
Down syndrome (DS) subjects are more likely to develop the clinical features of Alzheimer's disease (AD) very early in the disease process due to the additional impact of neuroinflammation and because of activation of innate...
Iron ferritin Alzheimer’s disease Hepcidin iron homeostasis Choroid Plexus trisomy 21 Olig2 RUNX1 S100β accelerating ageing down syndrome dementia erythroid-megakaryocyte
Published by: Journal of clinical medicine
Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia.
Ruma Raha-Chowdhury, Animesh Alexander Raha, James Henderson, Seyedeh Deniz Ghaffari, Monika Grigorova, Jessica Beresford-Webb, Kieren Allinson, Subhojit Chakraborty, Anthony Holland, Shahid H Zaman
Sep 20, 2021
Down syndrome (DS) subjects are more likely to develop the clinical features of Alzheimer's disease (AD) very early in the disease process due to the additional impact of neuroinflammation and because of activation of innate...
Hepcidin Increases Cytokines in Alzheimer's Disease and Down's Syndrome Dementia
Animesh Alexander Raha, Seyedeh Deniz Ghaffari, James Henderson, Subhojit Chakraborty, Kieren Allinson, Robert P Friedland, Anthony Holland, Shahid H Zaman, Elizabeta B Mukaetova-Ladinska, Ruma Raha-Chowdhury
May 27, 2021
The liver-derived hormone hepcidin, a member of the defensin family of antimicrobial peptides, plays an important role in host defense and innate immunity due to its broad antibacterial and antiviral properties. Ferritin, an...
Impaired Iron Homeostasis and Haematopoiesis Impacts Inflammation in the Ageing Process in Down Syndrome Dementia
Ruma Raha-Chowdhury, Animesh Alexander Raha, James Henderson, Seyedeh Deniz Ghaffari, Monika Grigorova, Jessica Beresford-Webb, Kieren Allinson, Subhojit Chakraborty, Anthony Holland, Shahid H. Zaman
Jul 02, 2021
Down syndrome (DS) subjects are more likely to develop the clinical features of Alzheimer’s disease (AD) very early in the disease process due to the additional impact of neuroinflammation and because of activation of innate...
Interplay of Ferritin Accumulation and Ferroportin Loss in Ageing Brain
Animesh Alexander Raha, Anwesha Biswas, James Henderson, Subhojit Chakraborty, Anthony Holland, Robert P Friedland, Elizabeta Mukaetova-Ladinska, Shahid Zaman, Ruma Raha-Chowdhury
Jan 28, 2022
Iron accumulates in the ageing brain and in brains with neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and Down syndrome (DS) dementia. However, the mechanisms...
G-protein α-subunit (GPA1) regulates stress, nitrate and phosphate response, flavonoid biosynthesis, fruit/seed development and substantially shares GCR1 regulation in A. <i>thaliana</i>
Navjyoti Chakraborty, Priyanka Sharma, Kostya Kanyuka, Ravi Ramesh Pathak, Devapriya Choudhury, Richard Hooley, Nandula Raghuram
Dec 01, 2015
Heterotrimeric G-proteins are implicated in several plant processes, but the mechanisms of signal-response coupling and the roles of G-protein coupled receptors in general and GCR1 in particular, remain poorly understood. We...
G-protein α-subunit (GPA1) regulates stress, nitrate and phosphate response, flavonoid biosynthesis, fruit/seed development and substantially shares GCR1 regulation in A. <i>thaliana</i>
Navjyoti Chakraborty, Priyanka Sharma, Kostya Kanyuka, Ravi Ramesh Pathak, Devapriya Choudhury, Richard Hooley, Nandula Raghuram
Dec 01, 2015
Heterotrimeric G-proteins are implicated in several plant processes, but the mechanisms of signal-response coupling and the roles of G-protein coupled receptors in general and GCR1 in particular, remain poorly understood. We...
Studies Towards the Discovery of Novel Natural Products Through Functional Analysis of Environmental DNA-Encoded Type II Polyketide Synthases
Debjani Chakraborty
Jan 01, 0001
Natural products have historically served as a major source for most of the therapeutically relevant compounds. A significant fraction of these natural product-based drugs and leads are derived from microorganisms. Although the...
Published by: Rockefeller University
An Approach to Prevent Air Pollution and Generate Electricity Using Nanostructured Carbon Materials
Pollution is one of the major threats for the environment as well as society. It causes severe problems for the living organisms and can gives birth of various unknown issues. Different sources like cars, industrial belts...
Published by: IGI Global Scientific Publishing
Charge transport in cancer-related genes and early carcinogenesis
The electronic transmission properties of DNA molecules are believed to play a significant role in many physical phenomena taking place in living organisms (Chakraborty, 2007) [1]. Here we study the charge transport (CT)...
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