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Historical zoonoses and other changes in host tropism of <em>Staphylococcus aureus</em>, identified by phylogenetic analysis of a population dataset

Background:Staphylococcus aureus exhibits tropisms to many distinct animal hosts. While spillover events can occur wherever there is an interface between host species, changes in host tropism only occur with...

Historical zoonoses and other changes in host tropism of <em>Staphylococcus aureus</em>, identified by phylogenetic analysis of a population dataset

Background:Staphylococcus aureus exhibits tropisms to many distinct animal hosts. While spillover events can occur wherever there is an interface between host species, changes in host tropism only occur with...

Decomposing the Humanities
S Connor
Feb 07, 2017
Drawing deeply from the example of Michel Serres, Bruno Latour’s work represents a critique of the commitment to critique which has become the dominant mode of much work in the humanities. Latour’s An Inquiry into Modes of...
Towards the Homotopy Type of the Morse Complex
Connor Donovan
Jan 01, 0001
Mathematicians have long been interested in studying the properties of simplicial complexes. In 1998, Robin Forman developed gradient vector fields as a tool to study these complexes. Having gradient vector fields to study these...
Published by: Ursinus College
Characterizing the Interaction of MAGUK Scaffold Protein PSD-95 With Synaptic Adhesion Protein Slitrk2
Connor Loomis
Jan 01, 0001
In the developing nervous system, synapse formation is crucial to establish proper brain wiring and therefore function. At synapses, several pre- and postsynaptic adhesion proteins are expressed to coordinate synapse formation....
Published by: Ursinus College
Communicating Climate to Ourselves and Others
Connor Bernier
Jan 01, 0001
My Summer Fellows experience has focused on the essential importance of communication in the climate crisis, and on personal exploration to reconnect with the natural world. Grounding practices such as hiking in the woods and...
Published by: Ursinus College
Penalized smoothing splines resolve the curvature identifiability problem in age-period-cohort models with unequal intervals

Age-period-cohort (APC) models are frequently used in a variety of health and demographic-related outcomes. Fitting and interpreting APC models to data in equal intervals (equal age and period widths) is nontrivial due to the...

Penalized smoothing splines resolve the curvature identifiability problem in age-period-cohort models with unequal intervals

Age-period-cohort (APC) models are frequently used in a variety of health and demographic-related outcomes. Fitting and interpreting APC models to data in equal intervals (equal age and period widths) is nontrivial due to the...

A Discrete Morse Approach for Computing Homotopy Types: An Exploration of the Morse, Generalized Morse, Matching, and Independence Complexes
Connor Donovan
Jan 01, 0001
In this thesis, we study possible homotopy types of four families of simplicial complexes-the Morse complex, the generalized Morse complex, the matching complex, and the independence complex-using discrete Morse theory. Given a...
Published by: Ursinus College
Yeast: The Gateway to Redefining and Improving Biology Labs
Connor Loomis
Jan 01, 0001
Building off of collegiate research performed during the summer of 2018, this lesson plan outlines a lab for secondary students using yeast. Yeast is an affordable and convenient organism to introduce to secondary education, and...
Published by: Ursinus College
Immunohistochemistry Staining for DCX and GFAP in Axolotl Spinal Cord Reveals Migration Pattern of New Neurons and Radial Glial Cells in Regenerating Tissue
Connor Evangelisto
Jan 01, 0001
Ambystoma mexicanum, commonly known as the Axolotl, possesses the unique ability to regenerate extremities and heal wounds at a rapid rate. Axolotls are considered paedomorphic salamanders, maintaining the juvenile features of...
Published by: Ursinus College
Role of protein concentration on transient film thickness in synovial fluid lubricated joints
A computational model of protein aggregation lubrication has been developed for predicting transient behaviour in lubricated prosthetics. The model uses an advection-diffusion equation to simulate protein transport in order to...
Neuroimaging in schizophrenia
Over the last five decades, a large body of evidence has accrued for structural and metabolic brain alterations in schizophrenia. Here we provide an overview of these findings, focusing on measures that have traditionally been...
Origin and function of the yolk sac in primate embryogenesis.
Human embryogenesis is hallmarked by two phases of yolk sac development. The primate hypoblast gives rise to a transient primary yolk sac, which is rapidly superseded by a secondary yolk sac during gastrulation. Moreover...

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