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De Finetti and Savage on the normative relevance of imprecise reasoning
This paper examines the claim that de Finetti and Savage completely rejected the notion of indeterminate, as distinct from imprecise, probabilities. It argues that their examination of imprecise reasoning refers both to...
An integrated dimensionality reduction and surrogate optimization approach for plant-wide chemical process operation
Abstract: With liquefied natural gas becoming increasingly prevalent as a flexible source of energy, the design and optimization of industrial refrigeration cycles becomes even more important. In this article, we propose an...
Telerehabilitation after total knee replacement in Italy
OBJECTIVES: To assess cost-effectiveness and cost utility of telerehabilitation (TR) versus standard rehabilitation (SR) after total knee replacement (TKR). DESIGN: Markov decision modelling of cost-effectiveness and...
health economics rehabilitation medicine Arthroplasty Replacement Knee Cost-Benefit Analysis Female Humans Italy Male Markov Chains Models Economic Physical Therapy Modalities Practice Guidelines as Topic Primary Health Care Program Evaluation Quality of life Telerehabilitation Treatment Outcome
Published by: BMJ Open
Evaluation of a worldwide EQA scheme for complex clonality analysis of clinical lymphoproliferative cases demonstrates a learning effect.
Cleo Keppens, Elke Boone, Paula Gameiro, Véronique Tack, Elisabeth Moreau, Elizabeth Hodges, Paul Evans, Monika Brüggemann, Ian Carter, Dido Lenze, Maria Eugenia Sarasquete, Markus Möbs, Hongxiang Liu, Elisabeth MC Dequeker, Patricia JTA Groenen
Aug 14, 2021
Clonality analysis of immunoglobulin (IG) or T-cell receptor (TR) gene rearrangements is routine practice to assist diagnosis of lymphoid malignancies. Participation in external quality assessment (EQA) aids laboratories in...
Clonality analysis external quality assessment IG rearrangements TCR rearrangements Gene Rearrangement Genes Immunoglobulin Genes T-Cell Receptor Humans Laboratory Proficiency Testing Lymphoproliferative Disorders Molecular Diagnostic Techniques Observer Variation Polymerase Chain Reaction Predictive Value of Tests Quality Assurance Health Care Quality Control Reproducibility of Results
Quantification of protein-protein interactions and activation dynamics
Oncogene dysregulation is a driver of neoplasia development and progression. The use of quantitative molecular imaging to quantify oncogene activation will be crucial in developing companion diagnostics which can identify...
Winthrop Recognizes Exceptional Employees During Annual Ceremony
Winthrop University
Jan 01, 0001
Winthrop University honored 41 employees with presidential citations during the April 23 Faculty, Staff and Retirees Awards Ceremony. Retirees Glenn Savage and Lynn Harand were co-recipients of the Mary Spann Richardson Award....
Published by: Winthrop University
Quantification of protein-protein interactions and activation dynamics
Oncogene dysregulation is a driver of neoplasia development and progression. The use of quantitative molecular imaging to quantify oncogene activation will be crucial in developing companion diagnostics which can identify...
What made Stan Wood a great collector?
Stan Wood was an exceptional fossil collector who, over a collecting career of more than 40 years, provided British palaeontology with an abundance and variety of new Carboniferous fossils the like of which had not been...
Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice.
David Savage
Oct 06, 2022
Objectives
Obesity in humans and mice is associated with elevated levels of two hormones responsive to cellular stress, namely GDF15 and FGF21. Over-expression of each of these is associated with weight loss and beneficial...
Information Sharing on Social Media by Multicultural Individuals
Drawing upon social cognitive & social network theories, this study examines individual-level and network-level factors which potentially affect multicultural individuals’ information sharing behavior via social media. The data...
Published by: IGI Global Scientific Publishing
The Effect of Technology Readiness on Individual Absorptive Capacity Toward Learning Behavior in Australian Universities
Recipient's absorptive capacity (ACAP) is a barrier to knowledge transfer in organizations. The technology readiness (TR) dimensions measure an individual's technological beliefs and aligns with the individual's ACAP. The...
Published by: IGI Global Scientific Publishing
The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions.
Julie Dubois-Chevalier, Vanessa Dubois, Hélène Dehondt, Parisa Mazrooei, Claire Mazuy, Aurélien A Sérandour, Céline Gheeraert, Penderia Guillaume, Eric Baugé, Bruno Derudas, Nathalie Hennuyer, Réjane Paumelle, Guillemette Marot, Jason S Carroll, Mathieu Lupien, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Jul 12, 2019
Control of gene transcription relies on concomitant regulation by multiple transcriptional regulators (TRs). However, how recruitment of a myriad of TRs is orchestrated at cis-regulatory modules (CRMs) to account for...
Sex Differences in Autism Spectrum Disorder based on DSM-5 Criteria
In the absence of intellectual impairment autism spectrum disorder (ASD) is diagnosed both less and later in females. This study used clinician and teacher report to explore sex differences in the behavioural presentation of 69...
Sex Differences in Autism Spectrum Disorder based on DSM-5 Criteria
In the absence of intellectual impairment autism spectrum disorder (ASD) is diagnosed both less and later in females. This study used clinician and teacher report to explore sex differences in the behavioural presentation of 69...
Glacier characteristics and retreat between 1991 and 2014 in the Ladakh Range, Jammu and Kashmir
Glaciers in the Ladakh Range lie between the Himalaya, a monsoon-forced region of glacier retreat, and the Karakoram, a region of anomalous glacier stability driven by mid-latitude westerlies. Given this context, glaciers might...
Genetic syndromes of severe insulin resistance.
Insulin resistance underpins the link between obesity and most of its associated metabolic disorders including type 2 diabetes, fatty liver disease, dyslipidaemia and cardiovascular disease. Despite its importance and extensive...
Vernon Lee's Problem with Landor
Alex T Wong
Feb 03, 2016
This article considers some fundamental elements of Vernon Lee’s critical theory by focussing attention on her criticisms of Walter Savage Landor, whose ‘classical’ or ‘rhetorical’ style she attributes to the writer’s lack of...
A consistent and robust measurement of the thermal state of the IGM at 2 ≤ z ≤ 4 from a large sample of Ly α forest spectra
We characterise the thermal state of the intergalactic medium (IGM) in ten
redshift bins in the redshift range $2 \leq z \leq 4$ with a sample of 103 high
resolution, high S/N Ly$\alpha$ forest spectra using four different...
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