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Ancient DNA reveals multiple origins and migration waves of extinct Japanese brown bear lineages
Takahiro Segawa, Takahiro Yonezawa, Hiroshi Mori, Ayumi Akiyoshi, Morten E. Allentoft, Ayako Kohno, Fuyuki Tokanai, Eske Willerslev, Naoki Kohno, Hidenori Nishihara
Aug 11, 2021
Little is known about how mammalian biogeography on islands was affected by sea-level fluctuations. In the Japanese Archipelago, brown bears (Ursus arctos) currently inhabit only Hokkaido, the northern island, but Pleistocene...
Ancient DNA reveals multiple origins and migration waves of extinct Japanese brown bear lineages.
Takahiro Segawa, Takahiro Yonezawa, Hiroshi Mori, Ayumi Akiyoshi, Morten E Allentoft, Ayako Kohno, Fuyuki Tokanai, Eske Willerslev, Naoki Kohno, Hidenori Nishihara
Sep 02, 2021
Little is known about how mammalian biogeography on islands was affected by sea-level fluctuations. In the Japanese Archipelago, brown bears (Ursus arctos) currently inhabit only Hokkaido, the northern island, but Pleistocene...
Ancient DNA reveals multiple origins and migration waves of extinct Japanese brown bear lineages.
Takahiro Segawa, Takahiro Yonezawa, Hiroshi Mori, Ayumi Akiyoshi, Morten E Allentoft, Ayako Kohno, Fuyuki Tokanai, Eske Willerslev, Naoki Kohno, Hidenori Nishihara
Sep 13, 2021
Little is known about how mammalian biogeography on islands was affected by sea-level fluctuations. In the Japanese Archipelago, brown bears (Ursus arctos) currently inhabit only Hokkaido, the northern island, but...
Published by: Royal Society open science
International origin and development of nationalism
Takahiro Kamisuna
Apr 18, 2023
East Timorese nationalism experienced a unique generational transition during Indonesia's occupation hinging onto internationalism in the changing world. In contrast to the existing literature on nationalism, which is...
A Destruction Model of the Vascular and Lymphatic Systems in the Emergence of Psychiatric Symptoms.
The lymphatic system is important for antigen presentation and immune surveillance. The lymphatic system in the brain was originally introduced by Giovanni Mascagni in 1787, while the rediscovery of it by Jonathan Kipnis and...
Dissipation controls transport and phase transitions in active fluids
Abstract
Active fluids operate by constantly dissipating energy at the particle level to perform a directed motion, yielding dynamics and phases without any equilibrium equivalent....
Impact of loss-to-follow-up on cancer survival estimates for small populations
Objectives: The accuracy of the ascertainment of vital status impacts the validity of cancer survival. This study assesses the potential impact of loss-to-follow-up on survival in Japan, both nationally and in the samples seen...
Reconstructing long-term dengue virus immunity in French Polynesia.
Takahiro Nemoto, Maite Aubry, Yoann Teissier, Richard Paul, Van-Mai Cao-Lormeau, Henrik Salje, Simon Cauchemez
Nov 03, 2022
BACKGROUND: Understanding the underlying risk of infection by dengue virus from surveillance systems is complicated due to the complex nature of the disease. In particular, the probability of becoming severely sick is driven by...
Towards prognostic functional brain biomarkers for cervical myelopathy
Shota Takenaka, Shigeyuki Kan, Ben Seymour, Takahiro Makino, Yusuke Sakai, Junichi Kushioka, Hisashi Tanaka, Yoshiyuki Watanabe, Masahiko Shibata, Hideki Yoshikawa, Takashi Kaito
Aug 02, 2019
Recently, there has been increasing interest in strategies to predict neurological recovery in cervical myelopathy (CM) based on clinical images of the cervical spine. In this study, we aimed to explore potential preoperative...
Median eminence myelin continuously turns over in adult mice.
Sophie Buller, Sara Kohnke, Robert Hansford, Takahiro Shimizu, William D Richardson, Clemence Blouet
Mar 08, 2023
OBJECTIVE: Oligodendrocyte progenitor cell differentiation is regulated by nutritional signals in the adult median eminence (ME), but the consequences on local myelination are unknown. The aim of this study was to characterize...
Development of an Information Research Platform for Data-Driven Agriculture
Takahiro Kawamura, Tetsuo Katsuragi, Akio Kobayashi, Motoko Inatomi, Masataka Oshiro, Hisashi Eguchi
Jan 01, 2022
Comprehensive research data are acknowledged as a necessity for research acceleration. Research institutes and universities are engaged in developing research data management systems. The National Agriculture and Food Research...
Published by: IGI Global Scientific Publishing
Biocompatible fluorescent silicon nanocrystals for single-molecule tracking and fluorescence imaging.
Hirohito Nishimura, Ken Ritchie, Rinshi S Kasai, Miki Goto, Nobuhiro Morone, Hiroyuki Sugimura, Koichiro Tanaka, Ichiro Sase, Akihiko Yoshimura, Yoshitaro Nakano, Takahiro K Fujiwara, Akihiro Kusumi
May 28, 2019
Fluorescence microscopy is used extensively in cell-biological and biomedical research, but it is often plagued by three major problems with the presently available fluorescent probes: photobleaching, blinking, and large size....
Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.
Takahiro K Fujiwara, Kokoro Iwasawa, Ziya Kalay, Taka A Tsunoyama, Yusuke Watanabe, Yasuhiro M Umemura, Hideji Murakoshi, Kenichi GN Suzuki, Yuri L Nemoto, Nobuhiro Morone, Akihiro Kusumi
May 28, 2019
The mechanisms by which the diffusion rate in the plasma membrane (PM) is regulated remain unresolved, despite their importance in spatially regulating the reaction rates in the PM. Proposed models include entrapment in...
Towards prognostic functional brain biomarkers for cervical myelopathy
Shota Takenaka, Shigeyuki Kan, Ben Seymour, Takahiro Makino, Yusuke Sakai, Junichi Kushioka, Hisashi Tanaka, Yoshiyuki Watanabe, Masahiko Shibata, Hideki Yoshikawa, Takashi Kaito
Jul 17, 2020
Abstract: Recently, there has been increasing interest in strategies to predict neurological recovery in cervical myelopathy (CM) based on clinical images of the cervical spine. In this study, we aimed to explore potential...
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology.
Lisa Tilokani, Fiona M Russell, Stevie Hamilton, Daniel M Virga, Mayuko Segawa, Vincent Paupe, Anja V Gruszczyk, Margherita Protasoni, Luis-Carlos Tabara, Mark Johnson, Hanish Anand, Michael P Murphy, D Grahame Hardie, Franck Polleux, Julien Prudent
Dec 12, 2022
Mitochondria are dynamic organelles that undergo membrane remodeling events in response to metabolic alterations to generate an adequate mitochondrial network. Here, we investigated the function of mitochondrial fission...
Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.
Timothy M Moore, Lijing Cheng, Dane M Wolf, Jennifer Ngo, Mayuko Segawa, Xiaopeng Zhu, Alexander R Strumwasser, Yang Cao, Bethan L Clifford, Alice Ma, Philip Scumpia, Orian S Shirihai, Thomas Q de Aguiar Vallim, Markku Laakso, Aldons J Lusis, Andrea L Hevener, Zhenqi Zhou
Dec 08, 2022
Parkin, an E3 ubiquitin ligase, plays an essential role in mitochondrial quality control. However, the mechanisms by which Parkin connects mitochondrial homeostasis with cellular metabolism in adipose tissue remain unclear....
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason T Lee, Masha V Poyurovsky, Kellen Olszewski, Travis Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Apr 03, 2023
Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason T Lee, Masha V Poyurovsky, Kellen Olszewski, Travis Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Apr 15, 2023
Mitochondria are critical to the governance of metabolism and bioenergetics in cancer cells1. The mitochondria form highly organized networks, in which their outer and inner membrane structures define their...
Mitochondria Humans Carcinoma Non-Small-Cell Lung Lung Neoplasms Glucose Fatty Acids Positron-Emission Tomography Microscopy Electron Energy Metabolism Oxidative Phosphorylation Phenotype Lipid Droplets
Published by: Nature
Spatial mapping of mitochondrial networks and bioenergetics in lung cancer.
Mingqi Han, Eric A Bushong, Mayuko Segawa, Alexandre Tiard, Alex Wong, Morgan R Brady, Milica Momcilovic, Dane M Wolf, Ralph Zhang, Anton Petcherski, Matthew Madany, Shili Xu, Jason T Lee, Masha V Poyurovsky, Kellen Olszewski, Travis Holloway, Adrian Gomez, Maie St John, Steven M Dubinett, Carla M Koehler, Orian S Shirihai, Linsey Stiles, Aaron Lisberg, Stefano Soatto, Saman Sadeghi, Mark H Ellisman, David B Shackelford
Mar 22, 2023
Genetic and antigenic characterisation of influenza A(H3N2) viruses isolated in Yokohama during the 2016/17 and 2017/18 influenza seasons.
Chiharu Kawakami, Seiya Yamayoshi, Miki Akimoto, Kazuya Nakamura, Hideka Miura, Seiichiro Fujisaki, David J Pattinson, Kohei Shimizu, Hiroki Ozawa, Tomoko Momoki, Miwako Saikusa, Atsuhiro Yasuhara, Shuzo Usuku, Ichiro Okubo, Takahiro Toyozawa, Shigeo Sugita, Derek J Smith, Shinji Watanabe, Yoshihiro Kawaoka
Feb 23, 2019
BACKGROUND: Influenza A(H3N2) virus rapidly evolves to evade human immune responses, resulting in changes in the antigenicity of haemagglutinin (HA). Therefore, continuous genetic and antigenic analyses of A(H3N2) virus are...
H3N2 HA Japan antigenicity EPIDEMIOLOGY Glycosylation haemagglutinin Influenza Influenza virus SURVEILLANCE viral infections Epidemics genetic variation Hemagglutinin Glycoproteins Influenza Virus Hemagglutinins Humans Influenza A virus H3N2 Subtype Influenza Human Japan Molecular Sequence Data Phylogeny RNA Viral Reverse Transcriptase Polymerase Chain Reaction Seasons Sequence Analysis DNA
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