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Stochastic Resilience in Operations Management Using Ito Diffusion and Gamma Catastrophe Processes
This study introduces a novel Ito diffusion model for operations management, addressing the challenge of maintaining resilience in supply chains and production networks against unpredictable disruptions. The model incorporates a...
Published by: IGI Global Scientific Publishing
ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Alisa F Zyryanova, Kazuhiro Kashiwagi, Claudia Rato, Heather P Harding, Ana Crespillo-Casado, Luke A Perera, Ayako Sakamoto, Madoka Nishimoto, Mayumi Yonemochi, Mikako Shirouzu, Takuhiro Ito, David Ron
Oct 26, 2020
The small molecule ISRIB antagonizes the activation of the integrated stress response (ISR) by phosphorylated translation initiation factor 2, eIF2(αP). ISRIB and eIF2(αP) bind distinct sites in their common target, eIF2B, a...
CRISPR/Cas9-homologous recombination cell stress drug action Eukaryotic Initiation Factor-2B mRNA translation Phosphorylation Protein Binding protein biosynthesis/drug effects Protein Conformation Acetamides Allosteric Regulation Animals Binding Sites CHO Cells Cricetulus Cryoelectron Microscopy Cyclohexylamines Eukaryotic Initiation Factor-2 Eukaryotic Initiation Factor-2B HeLa Cells Humans Phosphorylation
Clinical spectrum of MTOR-related hypomelanosis of Ito with neurodevelopmental abnormalities.
Virginie Carmignac, Cyril Mignot, Emmanuelle Blanchard, Paul Kuentz, Marie-Hélène Aubriot-Lorton, Victoria ER Parker, Arthur Sorlin, Sylvie Fraitag, Jean-Benoît Courcet, Yannis Duffourd, Diana Rodriguez, Rachel G Knox, Satyamaanasa Polubothu, Anne Boland, Robert Olaso, Marc Delepine, Véronique Darmency, Melissa Riachi, Chloé Quelin, Paul Rollier, Louise Goujon, Sarah Grotto, Yline Capri, Marie-Line Jacquemont, Sylvie Odent, Daniel Amram, Martin Chevarin, Catherine Vincent-Delorme, Benoît Catteau, Laurent Guibaud, Alexis Arzimanoglou, Malika Keddar, Catherine Sarret, Patrick Callier, Didier Bessis, David Geneviève, Jean-François Deleuze, Christel Thauvin, Robert K Semple, Christophe Philippe, Jean-Baptiste Rivière, Veronica A Kinsler, Laurence Faivre, Pierre Vabres
Aug 11, 2021
PURPOSE: Hypomelanosis of Ito (HI) is a skin marker of somatic mosaicism. Mosaic MTOR pathogenic variants have been reported in HI with brain overgrowth. We sought to delineate further the pigmentary skin phenotype and clinical...
Rational Design of Carbon Nitride Photoelectrodes with High Activity Toward Organic Oxidations
Carolina Pulignani, Camilo A Mesa, Sam AJ Hillman, Taylor Uekert, Sixto Giménez, James R Durrant, Erwin Reisner
Nov 15, 2022
Carbon nitride (CN x ) is a light‐absorber with excellent performance in photocatalytic suspension systems, but the activity of CN x photoelectrodes has remained low. Here, cyanamide‐functionalized CN x (NCNCN x ) was...
The Client and Service Provider Relationship in IT Outsourcing Project Success
The role of organizational attitude for an effective knowledge sharing (KS) in IT outsourcing (ITO) relationships has not been adequately addressed. In this paper, we investigate the relationship between KS and ITO success as...
Published by: IGI Global Scientific Publishing
ITO-ITO Dual-Plate Microgap Electrodes
Tin-doped indium oxide electrodes are fabricated and employed in a dual-plate microtrench geometry with the inter-electrode gap controlling the mass transport conditions in generator-collector mode. Electrodes are fabricated...
ITO-ITO Dual-Plate Microgap Electrodes
Tin-doped indium oxide electrodes are fabricated and employed in a dual-plate microtrench geometry with the inter-electrode gap controlling the mass transport conditions in generator-collector mode. Electrodes are fabricated...
Electro-optical characteristics of a liquid crystal cell with graphene electrodes.
Nune H Hakobyan, Hakob L Margaryan, Valeri K Abrahamyan, Vladimir M Aroutiounian, Arpi S Dilanchian Gharghani, Amalya B Kostanyan, Timothy D Wilkinson, Nelson Tabirian
Apr 01, 2020
In liquid crystal devices (LCDs) the indium tin oxide (ITO) films are traditionally used as transparent and conductive electrodes. However, today, due to the development of multichannel optical communication, the need for...
A Systematic Literature Review on IT Outsourcing Decision and Future Research Directions
During the recent decades, some academic research on the subject of information technology outsourcing (ITO) decision has appeared in different outlets, which may impede the use of such resources and as a result, repetition of...
Published by: IGI Global Scientific Publishing
Rational Design of Carbon Nitride Photoelectrodes with High Activity Toward Organic Oxidations.
Carolina Pulignani, Camilo A Mesa, Sam AJ Hillman, Taylor Uekert, Sixto Giménez, James R Durrant, Erwin Reisner
Nov 15, 2022
Carbon nitride (CNx ) is a light-absorber with excellent performance in photocatalytic suspension systems, but the activity of CNx photoelectrodes has remained low. Here, cyanamide-functionalized CNx (NCN CNx ) was co-deposited...
Precursors for p-Type Nickel Oxide
A series of unsymmetrical nickel beta-diketonate derivatives have been synthesised and structurally characterised for application as atmospheric-pressure metal-organic chemical vapour deposition (AP-MOCVD) precursors for nickel...
Precursors for p-Type Nickel Oxide
A series of unsymmetrical nickel beta-diketonate derivatives have been synthesised and structurally characterised for application as atmospheric-pressure metal-organic chemical vapour deposition (AP-MOCVD) precursors for nickel...
Exploring the Competitiveness of Cambodia as an IT Outsourcing Destination
Using assessment criteria from the A.T. Kearney global services location index, the authors explore Cambodia's competitiveness in the global IT outsourcing market (ITO), identifying how the country could become more competitive....
Published by: IGI Global Scientific Publishing
Infrared absorbing nanoparticle impregnated self-heating fabrics for significantly improved moisture management under ambient conditions
Lahiru A. Wijenayaka, Ruchira N. Wijesena, Nadeeka D. Tissera, W. R. L. Nisansala Bandara, Gehan J. Amaratunga, K. M. Nalin De Silva
May 20, 2021
Propensity of a textile material to evaporate moisture from its surface, commonly referred to as the ‘moisture management’ ability, is an important characteristic that dictates the applicability of a given textile material in...
An explicit construction of the McKay correspondence for <em>A-</em>Hilb C<sup>3</sup>
Alastair Craw
Mar 15, 2005
For a finite Abelian subgroup A of SL(3,C), Ito and Nakajima proved that the tautological bundles on the A-Hilbert scheme Y = A-Hilb(C^3) form a basis of the K-theory of Y. We establish the relations between these bundles in the...
Large ferro–pyro–phototronic effect in 0.5Ba(Zr<inf>0.2</inf>Ti<inf>0.8</inf>)O<inf>3</inf>–0.5(Ba<inf>0.7</inf>Ca<inf>0.3</inf>)TiO<inf>3</inf> thin films integrated on silicon for photodetection
Coupling together the ferroelectric, pyroelectric, and photovoltaic characteristics within a single material is a novel way to improve the performance of photodetectors. In this work, we take advantage of the triple...
Infrared absorbing nanoparticle impregnated self-heating fabrics for significantly improved moisture management under ambient conditions.
Lahiru A Wijenayaka, Ruchira N Wijesena, Nadeeka D Tissera, WRL Nisansala Bandara, Gehan J Amaratunga, KM Nalin De Silva
Jun 21, 2021
Propensity of a textile material to evaporate moisture from its surface, commonly referred to as the 'moisture management' ability, is an important characteristic that dictates the applicability of a given textile material in...
The expanding territories of condensin II.
This is the author accepted manuscript. The final version is available from Taylor & Francis via http://dx.doi.org/10.1080/15384101.2015.1063356
One-step preparation of the BiVO<sub>4</sub> film photoelectrode
Lucia H. Mascaro, Adam Pockett, John M. Mitchels, Laurence M. Peter, Petra J. Cameron, Veronica Celorrio, David J. Fermin, Jagdeep S. Sagu, K. G Upul Wijayantha, Gabriele Kociok-Kohn, Frank Marken
Jan 01, 2015
A one-step method of preparing photoelectrochemically active nanostructured BiVO4 films is reported based on thermolysis (500 °C in air) of a polyethylene glycol (PEG300) “paint-on” precursor solution containing...
An explicit construction of the McKay correspondence for <em>A-</em>Hilb C<sup>3</sup>
Alastair Craw
Mar 15, 2005
For a finite Abelian subgroup A of SL(3,C), Ito and Nakajima proved that the tautological bundles on the A-Hilbert scheme Y = A-Hilb(C^3) form a basis of the K-theory of Y. We establish the relations between these bundles in the...
Leptin-Mediated Changes in the Human Metabolome.
Katherine Lawler, Isabel Huang-Doran, Takuhiro Sonoyama, Tinh-Hai Collet, Julia M Keogh, Elana Henning, Stephen O'Rahilly, Leonardo Bottolo, I Sadaf Farooqi
May 15, 2020
CONTEXT: While severe obesity due to congenital leptin deficiency is rare, studies in patients before and after treatment with leptin can provide unique insights into the role that leptin plays in metabolic and endocrine...
bile acids Leptin Lipids Metabolomics obesity Adolescent Child Child Preschool Chromatography Liquid Energy Intake Energy Metabolism Female Hormone Replacement Therapy Humans Leptin Lipolysis Loss of Function Mutation Male Metabolome Metabolomics obesity Recombinant Proteins Severity of Illness Index Tandem Mass Spectrometry Treatment Outcome
Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities
Takuhiro Sonoyama, Lukas K. J. Stadler, Mingyan Zhu, Julia M. Keogh, Elana Henning, Fuki Hisama, Peter Kirwan, Magdalena Jura, Beata K. Blaszczyk, David C. DeWitt, Bas Brouwers, Marko Hyvönen, Inês Barroso, Florian T. Merkle, Suzanne M. Appleyard, Gary A. Wayman, I. Sadaf Farooqi
Jun 04, 2021
Abstract: Brain-derived neurotrophic factor (BDNF) signals through its high affinity receptor Tropomyosin receptor kinase-B (TrkB) to regulate neuronal development, synapse formation and plasticity. In rodents, genetic...
Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities.
Takuhiro Sonoyama, Lukas KJ Stadler, Mingyan Zhu, Julia M Keogh, Elana Henning, Fuki Hisama, Peter Kirwan, Magdalena Jura, Beata K Blaszczyk, David C DeWitt, Bas Brouwers, Marko Hyvönen, Inês Barroso, Florian T Merkle, Suzanne M Appleyard, Gary A Wayman, I Sadaf Farooqi
Jul 16, 2020
Brain-derived neurotrophic factor (BDNF) signals through its high affinity receptor Tropomyosin receptor kinase-B (TrkB) to regulate neuronal development, synapse formation and plasticity. In rodents, genetic disruption of Bdnf...
Disruption of genomic neighbourhood at the imprinted IGF<sub>2</sub>-H<sub>19</sub> locus in Beckwith-Wiedemann syndrome and Silver-Russell syndrome
Rafaella Nativio, Angela Sparago, Yoko Ito, Rosanna Weksberg, Andrea Riccio, Adele Murrell
Apr 01, 2011
Hyper- and hypomethylation at the IGF2-H19 imprinting control region (ICR) result in reciprocal changes in IGF2-H19 expression and the two contrasting growth disorders, Beckwith–Wiedemann syndrome (BWS) and Silver–Russell...
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