Search
Results: 140
From cradle to grave via the dissection room
The preponderance of men in the narrative of anatomical education during the 1800s has skewed the historical perception of medical cadavers in favour of adult men, and stifled the conversation about the less portrayed...
The afterlife of Laurence Sterne (1713-1768)
This paper aims to highlight the practice of body snatching from graves in the 1700s for the purpose of providing corpses for anatomical dissection, and for stocking anatomy museums. To do this, we examine the exhumation and...
Medieval injuries
OBJECTIVE: To explore how medieval living conditions, occupation, and an individual's role within society impacted their risk of skeletal trauma. MATERIALS: The skeletal remains of 314 individuals from medieval Cambridge that...
Medieval injuries
Abstract: Objective: To explore how medieval living conditions, occupation, and an individual's role within society impacted their risk of skeletal trauma. Materials: The skeletal remains of 314 individuals from medieval...
The prevalence of cancer in Britain before industrialization.
Piers D Mitchell, Jenna M Dittmar, Bram Mulder, Sarah Inskip, Alastair Littlewood, Craig Cessford, John E Robb
May 13, 2021
BACKGROUND: To plan for cancer services in the future, the long view of cancer prevalence is essential. It might be suspected that cancer prevalence before tobacco and industrial revolution pollutants was quite different to...
An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim.
Meriam Guellil, Marcel Keller, Jenna M Dittmar, Sarah A Inskip, Craig Cessford, Anu Solnik, Toomas Kivisild, Mait Metspalu, John E Robb, Christiana L Scheib
Mar 06, 2022
BACKGROUND: The human pathogen Haemophilus influenzae was the main cause of bacterial meningitis in children and a major cause of worldwide infant mortality before the introduction of a vaccine in the 1980s. Although the...
The greatest health problem of the Middle Ages? Estimating the burden of disease in medieval England.
OBJECTIVE: To identify the major health problems of the Middle Ages. Bubonic plague is often considered the greatest health disaster in medieval history, but this has never been systematically investigated. MATERIALS: We...
Development of a virtual sensor for the comparison of heat partitions in milling under cryogenic cooling lubrication and high-pressure cutting fluid supply
Thorsten Augspurger, Matthias Koch, Thomas Lakner, Andrea De Bartolomeis, Alborz Shokrani, Thomas Bergs
Nov 30, 2021
Manufacturing high precision and high performance parts in aerospace, automotive and medical industries often requires machining of difficult-to-cut materials such as titanium, nickel and hardened alloyed steel alloys. Low...
The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.
The precise relationship of embryonic stem cells (ESCs) to cells in the mouse embryo remains controversial. We present transcriptional and functional data to identify the embryonic counterpart of ESCs. Marker profiling shows...
Animals Biomarkers Blastocyst Inner Cell Mass Cell Differentiation Cell Line Cell Lineage Cell Proliferation Clone Cells Embryo Culture Techniques Embryo Implantation Embryonic Stem Cells Extracellular Signal-Regulated MAP Kinases Gene Expression Profiling Gene Expression Regulation Developmental Germ Layers Gestational Age Laminin Mice Mice 129 Strain Mice Inbred C57BL Mice Inbred CBA Phenotype Pluripotent Stem Cells Transcription Factors
Evaluating novelty
Building on a unique, multi-source, and multi-method study of R&D projects in a leading professional service firm, we develop the argument that organizations are more likely to fund projects with intermediate levels of...
Defence against antimicrobial peptides
The Firmicutes constitute a phylum of bacteria that can be found in a wide variety of habitats, from soil to the gastrointestinal tract of animals, where they have to thrive in complex communities. Competition in these...
Tritium O-Methylation of N-Alkoxy Maleimide Derivatives as Labeling Reagents for Biomolecules
An efficient procedure to access tritium-labeled maleimide derivatives in a high specific activity has been developed. N-Substituted maleimides containing the hydroxy functionality are O-methylated in a three-step synthesis...
Tritium O-Methylation of N-Alkoxy Maleimide Derivatives as Labeling Reagents for Biomolecules
An efficient procedure to access tritium-labeled maleimide derivatives in a high specific activity has been developed. N-Substituted maleimides containing the hydroxy functionality are O-methylated in a three-step synthesis...
Origin and function of the yolk sac in primate embryogenesis.
Human embryogenesis is hallmarked by two phases of yolk sac development. The primate hypoblast gives rise to a transient primary yolk sac, which is rapidly superseded by a secondary yolk sac during gastrulation. Moreover...
Determination of complex subclonal structures of hematological malignancies by multiplexed genotyping of blood progenitor colonies.
Alleles Clone Cells Cluster Analysis DNA Mutational Analysis DNA Neoplasm Erythroid Precursor Cells Genotyping Techniques Granulocytes Hematologic Neoplasms High-Throughput Nucleotide Sequencing Humans Janus Kinase 2 Mutation Mutation Missense Polycythemia Vera Polymorphism Single Nucleotide Sequence Analysis DNA
Gout and 'Podagra' in medieval Cambridge, England.
Jenna M Dittmar, Piers D Mitchell, Peter M Jones, Bram Mulder, Sarah A Inskip, Craig Cessford, John E Robb
Apr 26, 2021
OBJECTIVE: To estimate the prevalence rate of gout and to explore the social factors that contributed to its development in the various sub-populations in medieval Cambridge. MATERIALS: 177 adult individuals from four medieval...
The Prevalence of Cancer in Britain Before Industrialization
Piers D. Mitchell, Jenna M. Dittmar, Bram Mulder, Sarah Inskip, Alastair Littlewood, Craig Cessford, John E. Robb
May 04, 2021
BACKGROUND: To plan for cancer services in the future, the long view of cancer prevalence is essential. It might be suspected that cancer prevalence before tobacco and industrial revolution pollutants was quite different to...
Original Article Original Articles bone malignancy computed tomography (CT) imaging EPIDEMIOLOGY medieval metastases oncology
Published by: Cancer
Substitution of the native <i>srfA</i> promoter by constitutive P<i>veg</i> in two <i>B. subtilis </i>strains and evaluation of the effect on surfactin production
Judit Willenbacher, Teresa Mohr, Marius Henkel, Susanne Gebhard, Thorsten Mascher, Christoph Syldatk, Rudolf Hausmann
Apr 01, 2016
The genetic enhancement of Surfactin production increasingly gained attention in the last years, since relatively low product yields limit the industrial application of this biosurfactant. The natural quorum sensing regulation...
|
|< |
< |
1 |