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Results: 1792
A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells.
Gernot Walko, Samuel Woodhouse, Angela Oliveira Pisco, Emanuel Rognoni, Kifayathullah Liakath-Ali, Beate M Lichtenberger, Ajay Mishra, Stephanie B Telerman, Priyalakshmi Viswanathan, Meike Logtenberg, Lisa M Renz, Giacomo Donati, Sven R Quist, Fiona M Watt
Feb 07, 2019
Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular basis for this heterogeneity, we performed genome-wide pooled RNA interference screens and identified genes conferring a clonal...
YAP is essential for tissue tension to ensure vertebrate 3D body shape
Sean Porazinski, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S. F Gabriel Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina, Carl Philipp Heisenberg, Makoto Furutani-Seiki
May 14, 2015
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup which must in turn be correctly...
YAP is essential for tissue tension to ensure vertebrate 3D body shape
Sean Porazinski, Huijia Wang, Yoichi Asaoka, Martin Behrndt, Tatsuo Miyamoto, Hitoshi Morita, Shoji Hata, Takashi Sasaki, S. F Gabriel Krens, Yumi Osada, Satoshi Asaka, Akihiro Momoi, Sarah Linton, Joel B. Miesfeld, Brian A. Link, Takeshi Senga, Atahualpa Castillo-Morales, Araxi O. Urrutia, Nobuyoshi Shimizu, Hideaki Nagase, Shinya Matsuura, Stefan Bagby, Hisato Kondoh, Hiroshi Nishina, Carl Philipp Heisenberg, Makoto Furutani-Seiki
May 14, 2015
Vertebrates have a unique 3D body shape in which correct tissue and organ shape and alignment are essential for function. For example, vision requires the lens to be centred in the eye cup which must in turn be correctly...
‘It’s Only Chance That You’re Safe and Sound’
L Mellor
Oct 04, 2019
This article examines Humphrey Jennings’ film A Diary for Timothy (1945) and makes the case for understanding the form and aesthetic power of the film through the multiple meanings of the human body. Bodies — of the infant...
Small-Molecule Activation of YAP for Inner-Ear Regeneration and Beyond
Nathaniel Kastan
Jan 01, 0001
Hippo signaling is an evolutionarily conserved pathway that restricts organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent...
Published by: Rockefeller University
Small Molecule Activation of Yap for Inner-Ear Regeneration and Beyond
Nathaniel Kastan
Jan 01, 0001
Hippo signaling is an evolutionarily conserved pathway that restricts organ growth during development and suppresses regeneration in mature organs. Using a highthroughput phenotypic screen, we have identified a potent...
Published by: Rockefeller University
The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish
The precise regulation of numbers and types of neurons through control of cell cycle exit and terminal differentiation is an essential aspect of neurogenesis. The Hippo signaling pathway has recently been identified as...
Meta-Analysis and the Integration of Terrorism Event Databases
Timothy Jones
Jan 01, 2023
Why do terrorist attacks occur in certain places and times but not others? Despite advances in collection and empirical methods, the literature has produced divergent results and reached little consensus for common hypotheses...
Published by: IGI Global Scientific Publishing
The Hippo pathway controls a switch between retinal progenitor cell proliferation and photoreceptor cell differentiation in zebrafish
The precise regulation of numbers and types of neurons through control of cell cycle exit and terminal differentiation is an essential aspect of neurogenesis. The Hippo signaling pathway has recently been identified as...
The Light of the Leaf
The plant has recently emerged as a battleground of conflicting ecocriticisms. ‘Dark Ecology’ is, in the works of Timothy Morton, an ecocritical hermeneutic, in which the world can be subtracted into the parts of...
Ryan Haecker
Sep 14, 2021
Service, Leadership and Academics Honored at Student Life Awards
Winthrop University
Jan 01, 0001
Colleen Rice and Timothy Mention won the Mary Mildred Sullivan and Algernon Sydney Sullivan Awards. The award is given annually to students who have given great service to the university and plan to continue that great service...
Published by: Winthrop University
Integrating Service-Learning Pedagogy Into Community College Coursework
Developmental students face significant academic and life challenges as they pursue a college degree. As students in developmental studies often struggle to complete their courses, research focused on innovative pedagogy that...
Published by: IGI Global Scientific Publishing
Revisiting How Perceived Uncertainty and Herd Behavior Influence Technology Choice
Understanding how herd behavior occurs in the information systems context is important because such behavior influences many choice decisions, is the reason for some decision anomalies, and explains the reasons behind the rise...
Published by: IGI Global Scientific Publishing
The Impact of National Culture on Technological Service Innovation
The increasing use of blockchain technology in various industries has generated a significant amount of interest among researchers and practitioners. This study aims to determine a predictive classification model of...
Published by: IGI Global Scientific Publishing
Digital Badge Use in Specific Learner Groups
As educational technology continues to advance, new technologies continue to enter the scene that seek to enhance the delivery and reception of learning in both academic and industry settings. Digital badges are a recent...
Published by: IGI Global Scientific Publishing
Understanding Chinese University EFL Learners' Perceptions of AI in English Writing
Artificial intelligence (AI) is useful to English as a foreign language (EFL) learners, but there is a paucity of research on how they perceive AI. Contextualized in a Chinese university setting, this study investigated Chinese...
Published by: IGI Global Scientific Publishing
The Grizzly, November 14, 2024
Kate Horan, Connor McCarney, Sidney Belleroche, Caitlin Cunnane, Sophia Kumar, Stella Bower, Emily Veasey, Mary Lauren Franz, Kylie Ruggiero
Jan 01, 0001
"Keep Moving Forward" Hora De Café Bears on Trial A Dorm Cat's Story The Yap: A Recession of "Meet-Cute" Stories? Bears' Zelinske Defies the Odds Gymnastics Coach DeLorme Does It All
Ursinus College Collegeville Pennsylvania newspaper Dylan McHugh Football Xochitl Shuru pre-law studies Ella Schneider dating Alex Zelinske Swimming Alyssa DeLorme gymnastics cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Grizzly, October 31, 2024
Beetlejuice Breakout: Grizzly Edition Spooky Scary STDs UC Theater Presents an Agatha Christie Double Bill! The Monsters are Due on Main Street Creating "Bullshit" Opinions: The Yap With Emily Veasey Nerf Club: A Merry...
Ursinus College Collegeville Pennsylvania newspaper escape rooms peer advocates Safe Sex Theater department Naila Twyman horror fiction Halloween costumes nerf club lacrosse team Trinity Reformed Church cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Effect of Emotional Exhaustion and Knowledge Sharing on Depersonalization, Work Accomplishment, and Organizational Performance
The objective of the present study is to empirically investigate the relationship between emotional exhaustion and knowledge sharing of individual and organizational outcomes. Data was collected from 672 respondents from the...
Published by: IGI Global Scientific Publishing
Exploring the Relationship Between Organizational Politic and Knowledge Sharing in Brazilian Modular Consortium
This research aimed to explore the relationship between employees' perceptions of organizational politics (POPS) and their predisposition to involve in knowledge sharing (KS) behaviors at individuals and workgroups level in the...
Published by: IGI Global Scientific Publishing
Investigation of the Physical Learning Environment of Distance Learning Under COVID-19 and Its Influence on Students' Health and Learning Satisfaction
Most undergraduates in Mainland China receive distance education from home because of the COVID-19 outbreak. The unique physical environment of distance learning may have effects not only on student learning but also on student...
Published by: IGI Global Scientific Publishing
Using Customer Review Systems to Support Purchase Decisions
Online reviews have emerged as influential sources of information which greatly affect customers’ pre-purchase decision. Some studies have found that culture impacts online reviews, but many aspects of online review usage are...
Published by: IGI Global Scientific Publishing
Columbia Alumna Among Four Selected for Board of Trustee Seats
Winthrop University
Jan 01, 0001
Ashlye Rumph-Geddis Wilkerson `05 of Columbia, S.C., was selected for the Sixth District and will serve until 2014. In the remaining uncontested Board of Trustee races, these members will serve until 2018: Timothy B. Sease `87...
Published by: Winthrop University
The Grizzly, December 5, 2024
Kate Horan, Zach Cosme, Ashley Adam, Renee Washart, Emily Veasey, Sidney Belleroche, Hadley Whitman, Adam Denn
Jan 01, 0001
The Case of the Missing Lower Wismer Doors Seen the Zine? SAAC's Annual Holiday Food Drive Representation Exploration: Capstone Excerpt Campus Squirrels Pack Up for the Holidays The Yap With Emily Veasey...
Ursinus College Collegeville Pennsylvania newspaper Wismer dining hall zines Student Athlete Advisory Committee Diversity squirrels Social Media Wellness field hockey Basketball cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Orienting to Student Sense-Making
This chapter reports on work from a decade-long project to develop and study the use of teaching simulations focused on the teaching practices of eliciting and interpreting student thinking to support preservice teachers'...
Teacher Education Education Teacher Education Social Sciences and Humanities Physical Sciences and Engineering
Published by: IGI Global Scientific Publishing
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