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Results: 91
Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
Temo Barwari, Seda Eminaga, Ursula Mayr, Ruifang Lu, Paul C Armstrong, Melissa V Chan, Mahnaz Sahraei, Marta Fernández-Fuertes, Thomas Moreau, Javier Barallobre-Barreiro, Marc Lynch, Xiaoke Yin, Christian Schulte, Ferheen Baig, Raimund Pechlaner, Sarah R Langley, Anna Zampetaki, Peter Santer, Martin Weger, Roberto Plasenzotti, Markus Schosserer, Johannes Grillari, Stefan Kiechl, Johann Willeit, Ajay M Shah, Cedric Ghevaert, Timothy D Warner, Carlos Fernández-Hernando, Yajaira Suárez, Manuel Mayr
Jan 09, 2019
Fibrosis is a major contributor to organ disease for which no specific therapy is available. MicroRNA-21 (miR-21) has been implicated in the fibrogenetic response, and inhibitors of miR-21 are currently undergoing clinical...
Cardiology Cell Biology Fibrosis NONCODING RNAS platelets Aged Aged 80 and over Animals Blood Platelets Clinical Trials as Topic Extracellular Matrix Female FIBROBLASTS Fibrosis Humans Male Mice Mice Inbred C57BL MicroRNAs Middle Aged Myocardium Prospective Studies Proteomics RNA Untranslated Transforming Growth Factor beta1 Wiskott-Aldrich Syndrome Protein
Geographies of commemoration
Memorialising lives, deaths and events in landscapes can be authorised, official and highly regulated, or spontaneous, unsanctioned and anti-authoritarian. Interpreting and connecting two sites spanning the Pacific Ocean, this...
Oligodendrocytes Do Not Export NAA-Derived Aspartate In Vitro.
The conserved protein kinase-A target motif in synapsin of Drosophila is effectively modified by pre-mRNA editing.
Sören Diegelmann, Vanessa Nieratschker, Ursula Werner, Jürgen Hoppe, Troy Zars, Erich Buchner
Jun 14, 2011
A shorter working week for everyone
There are predictions that in future rapid technological development could result in a significant shortage of paid work. A possible option currently debated by academics, policy makers, trade unions, employers and mass media...
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells
Ana Amaral Porem Amaral, Mussie G Hadera, Joana M Tavares, Mark Kotter, Ursula Sonnewald
Sep 03, 2015
Genomic Analysis of Staphylococcus aureus of the Lineage CC130, Including mecC -Carrying MRSA and MSSA Isolates Recovered of Animal, Human, and Environmental Origins
Paula Gómez, Laura Ruiz-Ripa, Rosa Fernández-Fernández, Haythem Gharsa, Karim Ben Slama, Ursula Höfle, Myriam Zarazaga, Mark A. Holmes, Carmen Torres
Apr 08, 2021
Most methicillin resistant Staphylococcus aureus (MRSA) isolates harboring mecC gene belong to clonal complex CC130. This lineage has traditionally been regarded as animal-associated as it lacks the human specific immune evasion...
Zeta functions of alternate mirror Calabi–Yau families
Charles F Doran, Tyler L Kelly, Adriana Salerno, Steven Sperber, John Voight, Ursula Whitcher
May 15, 2018
We prove that if two Calabi-Yau invertible pencils have the same dual weights, then they share a common factor in their zeta functions. By using Dwork cohomology, we demonstrate that this common factor is related to a...
Recent Advances and Methodological Considerations on Vaccine Candidates for Human Schistosomiasis
Schistosomiasis remains a neglected tropical disease of major public health concern with high levels of morbidity in various parts of the world. Although considerable efforts in implementing mass drug administration...
Ursula Panzner, Jean-Louis Excler, Jerome H Kim, Florian Marks, Darrick Carter, Afzal A Siddiqui
Sep 09, 2021
Rare Diseases Clinical Research Orphan Drug Biotechnology Immunization Vector-Borne Diseases Biodefense Emerging Infectious Diseases Vaccine Related Infectious Diseases Prevention Digestive Diseases 3 Prevention of disease and conditions and promotion of well-being 5.1 Pharmaceuticals 5 Development of treatments and therapeutic interventions 3.4 Vaccines Infection 3 Good Health and Well Being
Characterization of glucose-related metabolic pathways in differentiated rat oligodendrocyte lineage cells.
13C acetate Energy Metabolism Glucose Glycolysis Mitochondria Oligodendroglia pyruvate carboxylation Acetates Acetyl Coenzyme A Animals Carbon Radioisotopes Cells Cultured Citric Acid Cycle Cytosol Glucose Lactic Acid Malates Mitochondria Neural Stem Cells Oligodendroglia Oxaloacetic Acid pentose phosphate pathway Phosphoenolpyruvate Pyruvic Acid Radiopharmaceuticals Rats Sprague-Dawley
Genomic Analysis of Staphylococcus aureus of the Lineage CC130, Including mecC-Carrying MRSA and MSSA Isolates Recovered of Animal, Human, and Environmental Origins.
Paula Gómez, Laura Ruiz-Ripa, Rosa Fernández-Fernández, Haythem Gharsa, Karim Ben Slama, Ursula Höfle, Myriam Zarazaga, Mark A Holmes, Carmen Torres
Mar 04, 2021
Most methicillin resistant Staphylococcus aureus (MRSA) isolates harboring mecC gene belong to clonal complex CC130. This lineage has traditionally been regarded as animal-associated as it lacks the human specific immune evasion...
PEARL MEISTER GREENGARD PRIZE
The Rockefeller University
Jan 01, 0001
The Pearl Meister Greengard Prize
An International Award Recognizing Outstanding Women in Biomedical Research
2014 recipient Lucy Shapiro, Ph.D.
The Pearl Meister Greengard Prize, awarded by The Rockefeller University, was...
Published by: The Rockefeller University
Guidelines for the functional annotation of microRNAs using the Gene Ontology.
Rachael P Huntley, Dmitry Sitnikov, Marija Orlic-Milacic, Rama Balakrishnan, Peter D'Eustachio, Marc E Gillespie, Doug Howe, Anastasia Z Kalea, Lars Maegdefessel, David Osumi-Sutherland, Victoria Petri, Jennifer R Smith, Kimberly Van Auken, Valerie Wood, Anna Zampetaki, Manuel Mayr, Ruth C Lovering
Jan 22, 2016
PEARL MEISTER GREENGARD PRIZE
The Rockefeller University
Jan 01, 0001
The Pearl Meister Greengard Prize
An International Award Recognizing Outstanding Women in Biomedical Research
2013 recipient Huda Yzoghbi, M.D.
The Pearl Meister Greengard Prize, awarded by The Rockefeller University, was...
Published by: The Rockefeller University
Current perspectives on invasive nontyphoidal Salmonella disease.
Andrea H Haselbeck, Ursula Panzner, Justin Im, Stephen Baker, Christian G Meyer, Florian Marks
Feb 19, 2019
PURPOSE OF REVIEW: We searched PubMed for scientific literature published in the past 2 years for relevant information regarding the burden of invasive nontyphoidal Salmonella disease and host factors associated with...
Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation.
Adam A Nabeebaccus, Anna Zoccarato, Anne D Hafstad, Celio Xc Santos, Ellen Aasum, Alison C Brewer, Min Zhang, Matteo Beretta, Xiaoke Yin, James A West, Katrin Schröder, Julian L Griffin, Thomas R Eykyn, E Dale Abel, Manuel Mayr, Ajay M Shah
Jan 15, 2018
Cardiac hypertrophic remodeling during chronic hemodynamic stress is associated with a switch in preferred energy substrate from fatty acids to glucose, usually considered to be energetically favorable. The mechanistic...
Cardiology cardiovascular disease Intermediary metabolism metabolism Signal Transduction Acetylglucosamine Adaptation Physiological Animals Cardiomegaly Energy Metabolism Fatty Acids Glucose Glycolysis Hexosamines Mice Knockout Mice Transgenic Myocardium Myocytes Cardiac NADPH Oxidase 4 Oxidation-Reduction Proteome Stress Physiological
Interplay of Kinetic and Thermodynamic Reaction Control Explains Incorporation of Dimethylammonium Iodide into CsPbI3.
Aditya Mishra, Dominik J Kubicki, Ariadni Boziki, Rohit D Chavan, Mathias Dankl, Marko Mladenović, Daniel Prochowicz, Clare P Grey, Ursula Rothlisberger, Lyndon Emsley
Sep 22, 2022
CsPbI3 is a promising material for optoelectronics owing to its thermal robustness and favorable bandgap. However, its fabrication is challenging because its photoactive phase is thermodynamically unstable at room temperature....
The EASL–<em>Lancet</em> Commission on liver health in Europe
Tom H Karlsen, Harry Rutter, Patrizia Carrieri, Shira Zelber-Sagi, Eivind Engebretsen, Sharon Hutchinson, Kristin Voigt, Neil Guha, Annalisa Berzigotti, Georg Schomerus, Pere Gines, Maria Buti, Patrizia Burra, Michael P Manns, Aleksander Krag, Sabine Kleinert
Feb 12, 2024
In December, 2021, the first report from the Lancet Commission on liver disease in Europe, a joint project with the European Association for the Study of the Liver (EASL), was published. 1 The Commission explored the harm to...
PEARL MEISTER GREENGARD PRIZE
The Rockefeller University
Jan 01, 0001
The Pearl Meister Greengard Prize
An International Award Recognizing Outstanding Women in Biomedical Research
2009 recipient Suzanne Cory, Ph.D., F.R.S.
Special Guest and Speaker Wafaa El-Sadr, M.D., M.P.H. Director...
Published by: The Rockefeller University
The EASL–<em>Lancet</em> Commission on liver health in Europe
Tom H Karlsen, Harry Rutter, Patrizia Carrieri, Shira Zelber-Sagi, Eivind Engebretsen, Sharon Hutchinson, Kristin Voigt, Neil Guha, Annalisa Berzigotti, Georg Schomerus, Pere Gines, Maria Buti, Patrizia Burra, Michael P Manns, Aleksander Krag, Sabine Kleinert
Feb 12, 2024
In December, 2021, the first report from the Lancet Commission on liver disease in Europe, a joint project with the European Association for the Study of the Liver (EASL), was published. 1 The Commission explored the harm to...
Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection.
Gretchen Hermes, James W Ajioka, Krystyna A Kelly, Ernest Mui, Fiona Roberts, Kristen Kasza, Thomas Mayr, Michael J Kirisits, Robert Wollmann, David JP Ferguson, Craig W Roberts, Jong-Hee Hwang, Toria Trendler, Richard P Kennan, Yasuhiro Suzuki, Catherine Reardon, William F Hickey, Lieping Chen, Rima McLeod
Jun 14, 2011
BACKGROUND: Worldwide, approximately two billion people are chronically infected with Toxoplasma gondii with largely unknown consequences. METHODS: To better understand long-term effects and pathogenesis of this common...
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