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NDUFAF5 Hydroxylates NDUFS7 at an Early Stage in the Assembly of Human Complex I.
Winthrop Student Wins Rhein Medall Grand Prize
Winthrop University
Jan 01, 0001
Winthrop student Juho Tuuha of Finland has won the first Rhein Medall Prize for the Charlotte region. Tuuha won for his 20-foot-tall stainless steel structure titled "Wings."
Published by: Winthrop University
Human METTL20 methylates lysine residues adjacent to the recognition loop of the electron transfer flavoprotein in mitochondria.
Bioenergetics Electron Transfer Flavoprotein Electron Transport System (ETS) Flavoprotein Methyltransferase Mitochondrial Metabolism Protein Methylation Trimethyllysine Amino Acid Sequence Base Sequence Cell Line Tumor Chromatography Affinity DNA Primers Electron Transport Flavoproteins Humans Lysine Mass Spectrometry Methylation Methyltransferases Mitochondria Molecular Sequence Data
Adherence monitoring methods to measure virological failure in people living with HIV on long-term antiretroviral therapy in Uganda.
Stephen Okoboi, Joseph Musaazi, Rachel King, Sheri A Lippman, Andrew Kambugu, Andrew Mujugira, Jonathan Izudi, Rosalind Parkes-Ratanshi, Agnes N Kiragga, Barbara Castelnuovo
Jan 04, 2023
Appointment keeping and self-report within 7-day or and 30-days recall periods are non-objective measures of antiretroviral treatment (ART) adherence. We assessed incidence of virological failure (VF), predictive performance and...
Adherence monitoring methods to measure virological failure in people living with HIV on long-term antiretroviral therapy in Uganda.
Stephen Okoboi, Joseph Musaazi, Rachel King, Sheri A Lippman, Andrew Kambugu, Andrew Mujugira, Jonathan Izudi, Rosalind Parkes-Ratanshi, Agnes N Kiragga, Barbara Castelnuovo
Apr 17, 2023
Appointment keeping and self-report within 7-day or and 30-days recall periods are non-objective measures of antiretroviral treatment (ART) adherence. We assessed incidence of virological failure (VF), predictive performance and...
Published by: PLOS global public health
Psychometric Validity of the Visual Function Index in Leber Hereditary Optic Neuropathy.
PURPOSE: The purpose of this study was to determine the psychometric validity of the Visual Function Index (VF-14) for use by patients with Leber hereditary optic neuropathy (LHON). METHODS: Rasch analysis was conducted in two...
A Collaborative Decision Support System Framework for Vertical Farming Business Developments
The emerging industry of vertical farming (VF) faces three key challenges: standardisation, environmental sustainability, and profitability. High failure rates are costly and can stem from premature business decisions about...
Published by: IGI Global Scientific Publishing
Human Immunodeficiency Virus-1 Viral Load Is Elevated in Individuals With Reverse-Transcriptase Mutation M184V/I During Virological Failure of First-Line Antiretroviral Therapy and Is Associated With Compensatory Mutation L74I.
BACKGROUND: M184V/I cause high-level lamivudine (3TC) and emtricitabine (FTC) resistance and increased tenofovir disoproxil fumarate (TDF) susceptibility. Nonetheless, 3TC and FTC (collectively referred to as XTC) appear to...
HIV antiretroviral compensatory mutation Drug Resistance Lamivudine Anti-HIV Agents CD4 Lymphocyte Count Drug Resistance Viral Drug Therapy Combination Emtricitabine HIV Infections HIV Reverse Transcriptase HIV-1 Humans Lamivudine Mutation Randomized Controlled Trials as Topic Reverse Transcriptase Inhibitors Tenofovir Treatment Failure Viral Load
NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I.
Complex I (NADH ubiquinone oxidoreductase) in mammalian mitochondria is an L-shaped assembly of 44 subunits. One arm is embedded in the inner membrane with the other protruding ∼100 Å into the matrix of the organelle. The...
assembly Bioenergetics Complex I Dimethylarginine Electron Transport Methyltransferase Mitochondria Protein Methylation Respiratory chain Arginine Cell Line Tumor Humans Methylation Methyltransferases NADH Dehydrogenase Protein Folding Protein Structure Secondary Protein-Arginine N-Methyltransferases
A planar impedance sensor for 3D spheroids.
Three dimensional cell culture systems have witnessed rapid expansion in the fields of tissue engineering and drug testing owing to their inherent ability to mimic native tissue microenvironments. High throughput technologies...
The Ursinus Weekly, April 22, 1904
Schaff society Union papers: The Education of a Roman Boy; Goethe's Faust Baseball The narrow outlook Board of Control of the Ursinus Weekly Supplement Zwinglian society Academy society Alumni YMCA Literary Supplement...
Ursinus College Collegeville Pennsylvania newspaper baseball Schaff literary society Zwinglian literary society YMCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
A Na+ conducting hydrogel for protection of organic electrochemical transistors.
I Del Agua, L Porcarelli, VF Curto, A Sanchez-Sanchez, E Ismailova, GG Malliaras, D Mecerreyes
Jul 18, 2018
Organic electrochemical transistors (OECTs) are being intensively developed for applications in electronics and biological interfacing. These devices rely on ions injected in a polymer film from an aqueous liquid electrolyte for...
Dynamic fragmentation of Al-W granular rings with different mesostructures
The support of this project was provided by the Office of Naval research Multidisciplinary University Research Initiative Award N00014-07-1-0740, Program Manager Dr. Clifford D. Bedford.
Adipose tissue dysfunction as a central mechanism leading to dysmetabolic obesity triggered by chronic exposure to p,p'-DDE
D Pestana, D Teixeira, M Meireles, C Marques, S Norberto, C Sá, VC Fernandes, L Correia-Sá, A Faria, L Guardão, JT Guimarães, WN Cooper, I Sandovici, VF Domingues, C Delerue-Matos, R Monteiro, M Constância, C Calhau
Aug 25, 2017
Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 as Outcome Predictors in Traumatic Brain Injury.
RSK Takala, JP Posti, H Runtti, VF Newcombe, JG Outtrim, AJ Katila, J Frantzén, H Ala-Seppälä, A Kyllönen, H-R Maanpää, J Tallus, MI Hossain, JP Coles, P Hutchinson, M van Gils, DK Menon, O Tenovuo
Dec 08, 2016
Biomarkers GFAP outcome Traumatic brain injury UCH-L1 Adolescent Adult Aged Area Under Curve Biomarkers Brain Injuries Female Glasgow Coma Scale Glial Fibrillary Acidic Protein Humans Injury Severity Score Logistic Models Male Middle Aged Predictive Value of Tests Prognosis Prospective Studies ROC Curve Ubiquitin Thiolesterase Young Adult
Effect of Radiation on Heat Transfer inside Aeroengine Compressor Rotors
The blade clearance in aero-engine compressors is mainly controlled by the radial growth of the compressor discs, to which the blades are attached. This growth depends on the radial distribution of the disc temperature, which in...
In Vivo Emergence of a Novel Protease Inhibitor Resistance Signature in HIV-1 Matrix.
Rawlings Datir, Steven Kemp, Kate El Bouzidi, Petra Mlchocova, Richard Goldstein, Judy Breuer, Greg J Towers, Clare Jolly, Miguel E Quiñones-Mateu, Patrick S Dakum, Nicaise Ndembi, Ravindra K Gupta
Nov 18, 2020
Protease inhibitors (PIs) are the second- and last-line therapy for the majority of HIV-infected patients worldwide. Only around 20% of individuals who fail PI regimens develop major resistance mutations in protease. We sought...
Africa Gag HIV antiretroviral antiretroviral resistance drug human immunodeficiency virus Protease Protease Inhibitors proteases resistance Amino Acid Substitution Dose-Response Relationship Drug Drug Resistance Viral Genome Viral Genotype HIV Antigens HIV Infections HIV-1 Humans Microbial Sensitivity Tests Mutation Phenotype Phylogeny Protease Inhibitors Sequence Deletion Viral Load gag Gene Products Human Immunodeficiency Virus
Genomics-informed outbreak investigations of SARS-CoV-2 using civet.
Áine O'Toole, Verity Hill, Ben Jackson, Rebecca Dewar, Nikita Sahadeo, Rachel Colquhoun, Stefan Rooke, JT McCrone, Kate Duggan, Martin P McHugh, Samuel M Nicholls, Radoslaw Poplawski, COVID-19 Genomics UK (COG-UK) Consortium, COVID-19 Impact Project (Trinidad & Tobago Group), David Aanensen, Matt Holden, Tom Connor, Nick Loman, Ian Goodfellow, Christine VF Carrington, Kate Templeton, Andrew Rambaut
Dec 09, 2022
Effect of Radiation on Heat Transfer inside Aeroengine Compressor Rotors
The blade clearance in aero-engine compressors is mainly controlled by the radial growth of the compressor discs, to which the blades are attached. This growth depends on the radial distribution of the disc temperature, which in...
Capturing the experiences of patients with inherited optic neuropathies
Benson S Chen, Tomasz Galus, Stephanie Archer, Valerija Tadić, Mike Horton, Konrad Pesudovs, Tasanee Braithwaite, Patrick Yu-Wai-Man
May 02, 2022
PURPOSE: To identify and comprehensively evaluate studies capturing the experience of individuals affected by an inherited optic neuropathy (ION), focusing on patient-reported outcome measures (PROMs) and qualitative studies...
Predictors of first-line antiretroviral therapy failure among adults and adolescents living with HIV/AIDS in a large prevention and treatment program in Nigeria.
Nicaise Ndembi, Fati Murtala-Ibrahim, Monday Tola, Jibreel Jumare, Ahmad Aliyu, Peter Alabi, Charles Mensah, Alash'le Abimiku, Miguel E Quiñones-Mateu, Trevor A Crowell, Soo-Yon Rhee, Robert W Shafer, Ravindra Gupta, William Blattner, Manhattan E Charurat, Patrick Dakum
Nov 30, 2020
BACKGROUND: A substantial number of persons living with HIV (PLWH) in Nigeria do not experience durable viral suppression on first-line antiretroviral therapy (ART). Understanding risk factors for first-line treatment failure...
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