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Singular value decomposition analysis of back projection operator of maximum likelihood expectation maximization PET image reconstruction.
Background In emission tomography maximum likelihood expectation maximization reconstruction technique has replaced the analytical approaches in several applications. The most important drawback of this iterative method is its...
A multi spin echo pulse sequence with optimized excitation pulses and a 3D cone readout for hyperpolarized 13 C imaging.
PURPOSE: Imaging tumor metabolism in vivo using hyperpolarized [1-13 C]pyruvate is a promising technique for detecting disease, monitoring disease progression, and assessing treatment response. However, the transient nature of...
Increasing the sensitivity of hyperpolarized [15 N2 ]urea detection by serial transfer of polarization to spin-coupled protons.
PURPOSE: Hyperpolarized 15 N-labeled molecules have been proposed as imaging agents for investigating tissue perfusion and pH. However, the sensitivity of direct 15 N detection is limited by the isotope's low gyromagnetic ratio....
Monitoring tumor cell death in murine tumor models using deuterium magnetic resonance spectroscopy and spectroscopic imaging.
Friederike Hesse, Vencel Somai, Felix Kreis, Flaviu Bulat, Alan J Wright, Kevin M Brindle
Mar 08, 2021
Genetic algorithm-based optimization of pulse sequences.
Vencel Somai, Felix Kreis, Adam Gaunt, Anastasia Tsyben, Ming Li Chia, Friederike Hesse, Alan J Wright, Kevin M Brindle
Dec 24, 2021
Comparison of 13 C MRI of hyperpolarized [1-13 C]pyruvate and lactate with the corresponding mass spectrometry images in a murine lymphoma model.
Maria Fala, Vencel Somai, Andreas Dannhorn, Gregory Hamm, Katherine Gibson, Dominique-Laurent Couturier, Richard Hesketh, Alan J Wright, Zoltan Takats, Josephine Bunch, Simon T Barry, Richard JA Goodwin, Kevin M Brindle
Dec 04, 2020