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Reconstructing aspects of human embryogenesis with pluripotent stem cells.
Berna Sozen, Victoria Jorgensen, Bailey AT Weatherbee, Sisi Chen, Meng Zhu, Magdalena Zernicka-Goetz
Aug 26, 2021
Understanding human development is of fundamental biological and clinical importance. Despite its significance, mechanisms behind human embryogenesis remain largely unknown. Here, we attempt to model human early embryo...
Adaptor Proteins Signal Transducing Biomarkers Blastocyst Cell Culture Techniques Cell Lineage Embryo Mammalian Embryonic Development GATA3 Transcription Factor Gene Expression Humans Models Biological Phospholipase C beta Pluripotent Stem Cells SOXB1 Transcription Factors SOXF Transcription Factors Sequence Analysis RNA Single-Cell Analysis
Reconstructing aspects of human embryogenesis with pluripotent stem cells.
Berna Sozen, Victoria Jorgensen, Bailey A T Weatherbee, Sisi Chen, Meng Zhu, Magdalena Zernicka-Goetz
Oct 23, 2021
Understanding human development is of fundamental biological and clinical importance. Despite its significance, mechanisms behind human embryogenesis remain largely unknown. Here, we attempt to model human early embryo...
Pluripotent Stem Cells Blastocyst Humans Adaptor Proteins Signal Transducing Cell Culture Techniques Sequence Analysis RNA Gene Expression Cell Lineage Embryonic Development Models Biological GATA3 Transcription Factor Embryo Mammalian Phospholipase C beta SOXB1 Transcription Factors SOXF Transcription Factors Single-Cell Analysis Biomarkers
Published by: Nature Communications
Genomics of Parallel Ecological Speciation in Lake Victoria Cichlids.
Joana Isabel Meier, David Alexander Marques, Catherine Elise Wagner, Laurent Excoffier, Ole Seehausen
Nov 27, 2019
The genetic basis of parallel evolution of similar species is of great interest in evolutionary biology. In the adaptive radiation of Lake Victoria cichlid fishes, sister species with either blue or red-back male nuptial...
Reconstructing aspects of human embryogenesis with pluripotent stem cells
Berna Sozen, Victoria Jorgensen, Bailey A. T. Weatherbee, Sisi Chen, Meng Zhu, Magdalena Zernicka-Goetz
Sep 21, 2021
Abstract: Understanding human development is of fundamental biological and clinical importance. Despite its significance, mechanisms behind human embryogenesis remain largely unknown. Here, we attempt to model human early embryo...
Patterns of the use of advanced radiation therapy techniques for the management of bone metastases and the associated factors in Victoria.
Tamara Fogarty, Mark Tacey, Giulia McCorkell, David Kok, Colin Hornby, Roger L Milne, Jeremy Millar, Farshad Foroudi, Wee Loon Ong
Feb 02, 2022
INTRODUCTION: To describe the pattern of the use of advanced radiation therapy (RT) techniques, including intensity-modulated RT (IMRT), volumetric modulated arc therapy (VMAT), and stereotactic body RT (SBRT) for the management...
Variations in whole brain radiation therapy fractionation for brain metastases in Victoria.
Lessandra Yan Shan Chee, Joseph Sia, Roger L Milne, Farshad Foroudi, Jeremy L Millar, Wee Loon Ong
Jun 29, 2022
INTRODUCTION: We aim to evaluate the use of different whole brain radiation therapy (WBRT) fractionation schedules for brain metastases (BM) in Victoria, and the factors associated with it. METHODS: This is a population-based...
How to Design a Research Plan for a Thesis in Social Sciences
María-Victoria Carrillo-Durán
Jan 01, 0001
This chapter presents the process of how a research work should be conceived in the mind of a novice researcher who wishes to do a doctoral thesis in social sciences. A logical-deductive scheme is followed, which guides the...
Communication Studies Library and Information Science Research Methods Media and Communications Social Sciences and Humanities
Published by: IGI Global Scientific Publishing
A Dense Linkage Map of Lake Victoria Cichlids Improved the Pundamilia Genome Assembly and Revealed a Major QTL for Sex-Determination.
Genetic linkage maps are essential for comparative genomics, high quality genome sequence assembly and fine scale quantitative trait locus (QTL) mapping. In the present study we identified and genotyped markers via...
Cichlidae Genetics of Sex RAD XY system amh recombination rate sex chromosome evolution sex determination Synteny Animals Chromosome Mapping Cichlids Databases Genetic evolution Molecular Genetic Linkage Genetic Markers Genomics Genotype High-Throughput Nucleotide Sequencing lakes Quantitative Trait Loci Recombination Genetic Sex Determination Processes Synteny
Location and character of volatile general anesthetics binding sites in the transmembrane domain of TRPV1
It has been proposed that general anesthesia results from direct multisite interactions with multiple and diverse ion channels in the brain. An understanding of the mechanisms by which general anesthetics modulate ion...
Location and character of volatile general anesthetics binding sites in the transmembrane domain of TRPV1
It has been proposed that general anesthesia results from direct multisite interactions with multiple and diverse ion channels in the brain. An understanding of the mechanisms by which general anesthetics modulate ion...
Influenza A (N1-N9) and Influenza B (B/Victoria and B/Yamagata) Neuraminidase Pseudotypes as Tools for Pandemic Preparedness and Improved Influenza Vaccine Design.
Kelly AS da Costa, Joanne Marie M Del Rosario, Matteo Ferrari, Sneha Vishwanath, Benedikt Asbach, Rebecca Kinsley, Ralf Wagner, Jonathan L Heeney, George W Carnell, Nigel J Temperton
Oct 24, 2022
To better understand how inhibition of the influenza neuraminidase (NA) protein contributes to protection against influenza, we produced lentiviral vectors pseudotyped with an avian H11 hemagglutinin (HA) and the NA of all...
Competency-Based Education
This chapter will review what competency-based education is and how delivering traditional educational credentials and degrees in a non-traditional, non-term program can better engage students and promote their success in the...
Higher Education Education Higher Education Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
Mechanism of molecular oxygen diffusion in a hypoxia sensing prolyl hydroxylase using multiscale simulation
The chronic response of animals to hypoxia is mediated by the αβ-heterodimeric hypoxia-inducible transcription factors (α,β-HIFs) which upregulate the expression of sets of genes that work to ameliorate the effects of...
Ancient hybridization fuels rapid cichlid fish adaptive radiations.
Joana I Meier, David A Marques, Salome Mwaiko, Catherine E Wagner, Laurent Excoffier, Ole Seehausen
Nov 27, 2019
Understanding why some evolutionary lineages generate exceptionally high species diversity is an important goal in evolutionary biology. Haplochromine cichlid fishes of Africa's Lake Victoria region encompass >700 diverse...
Mechanism of molecular oxygen diffusion in a hypoxia sensing prolyl hydroxylase using multiscale simulation
The chronic response of animals to hypoxia is mediated by the αβ-heterodimeric hypoxia-inducible transcription factors (α,β-HIFs) which upregulate the expression of sets of genes that work to ameliorate the effects of...
MosSCI and gateway compatible plasmid toolkit for constitutive and inducible expression of transgenes in the C. elegans germline.
Here we describe a toolkit for the production of fluorescently tagged proteins in the C. elegans germline and early embryo using Mos1-mediated single copy insertion (MosSCI) transformation. We have generated promoter and 3'UTR...
Technology and the Preparation of Students
The evolution of technology has situated learning to create a ubiquitous environment. The progression of technology will require preparation of students and teachers for the 21st century, including post-secondary students...
Published by: IGI Global Scientific Publishing
Transacting With Texts
This chapter presents an applied model for supporting preschool children's executive function, skills that serve as protective factors against risks associated with poverty, using Rosenblatt's transactional theory. The authors...
Culture & Population Studies Education Curriculum Development and Instructional Design Social Sciences and Humanities Media and Communications
Published by: IGI Global Scientific Publishing
Emerging Technologies
Emerging technologies enhance student learning through the explicit intentional educational design such as Active Learning Classrooms, Flipped Classrooms, Problem Based Learning, and Project Based Learning to empower students....
Published by: IGI Global Scientific Publishing
Two Dance Majors Receive 2010-11 Rose Family Scholarship
Winthrop University
Jan 01, 0001
This year, two dance students received the $500 one-year, endowed Rose Family Scholarship: Victoria Painter of Scotch Plains, N.J., and Emily Johnson of Olney, Md. The scholarship was established by the family of Winthrop dance...
Published by: Winthrop University
The Importance of Student Partnership in Rubric Construction, Discussion, and Evaluation
The chapter explores the importance of utilising student-staff partnerships in the development and evaluation of rubrics. The approach followed is underpinned by the University of Reading principles for student-staff...
classroom management Education Learning Assessment and Measurement Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
Development of a Biotechnology Platform for the Fast-Growing Cyanobacterium Synechococcus sp. PCC 11901.
Lauren A Mills, José Ángel Moreno-Cabezuelo, Artur Włodarczyk, Angelo J Victoria, Rebeca Mejías, Anja Nenninger, Simon Moxon, Paolo Bombelli, Tiago T Selão, Alistair J McCormick, David J Lea-Smith
Sep 02, 2022
Synechococcus sp. PCC 11901 reportedly demonstrates the highest, most sustained growth of any known cyanobacterium under optimized conditions. Due to its recent discovery, our knowledge of its biology, including the factors...
Telomere damage promotes vascular smooth muscle cell senescence and immune cell recruitment after vessel injury.
Anna K Uryga, Mandy O J Grootaert, Abel M Garrido, Sebnem Oc, Kirsty Foote, Joel Chappell, Alison Finigan, Francesca Rossiello, Fabrizio d'Adda di Fagagna, Dimitra Aravani, Helle F Jorgensen, Martin R Bennett
Jun 22, 2021
Accumulation of vascular smooth muscle cells (VSMCs) is a hallmark of multiple vascular pathologies, including following neointimal formation after injury and atherosclerosis. However, human VSMCs in advanced atherosclerotic...
Published by: Communications biology
Determinants of Non-paid Task Division in Gay-, Lesbian-, and Heterosexual-Parent Families With Infants Conceived Using Artificial Reproductive Techniques.
Loes Van Rijn-Van Gelderen, Kate Ellis-Davies, Marijke Huijzer-Engbrenghof, Terrence D Jorgensen, Martine Gross, Alice Winstanley, Berengere Rubio, Olivier Vecho, Michael E Lamb, Henny M Bos
Jul 29, 2020
Background: The division of non-paid labor in heterosexual parents in the West is usually still gender-based, with mothers taking on the majority of direct caregiving responsibilities. However, in same-sex couples, gender cannot...
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