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Cover Image for Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway.

Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway.

Amparo Romero-Picó, Marta G Novelle, Omar Al-Massadi, Daniel Beiroa, Marta Tojo, Violeta Heras, Francisco Ruiz-Pino, Ana Senra, Miguel López, Clemence Blouet, Manuel Tena-Sempere, Rubén Nogueiras, Carlos Diéguez

Apr 24, 2022

Weight gain is a hallmark of decreased estradiol (E2) levels because of menopause or following surgical ovariectomy (OVX) at younger ages. Of note, this weight gain tends to be around the abdomen, which is frequently associated...

Estrogens obesity energy expenditure P70s6k Kappa-opioid Animals Humans Mice Body Weight Weight Gain Receptors Opioid kappa Ovariectomy Energy Metabolism Eating Female Adipose Tissue Brown TOR Serine-Threonine Kinases

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Kappa-Opioid Receptor Blockade Ameliorates Obesity Caused by Estrogen Withdrawal via Promotion of Energy Expenditure through mTOR Pathway.

Jun 07, 2022

energy expenditure Estrogens Kappa-opioid obesity P70s6k Adipose Tissue Brown Animals Body Weight Eating Energy Metabolism Estrogens Female Humans Mice obesity Ovariectomy Receptors Opioid kappa TOR Serine-Threonine Kinases Weight Gain

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Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner.

Mar Quiñones, René Hernández-Bautista, Daniel Beiroa, Violeta Heras, Francisco L Torres-Leal, Brian YH Lam, Ana Senra, Johan Fernø, Alicia García Gómez-Valadés, Markus Schwaninger, Vincent Prevot, Giles Yeo, Marc Claret, Miguel López, Carlos Diéguez, Omar Al-Massadi, Ruben Nogueiras

Apr 26, 2021

Sirtuin 3 (SIRT3) is one of the seven mammalian sirtuin homologs of the yeast Sir2 gene that has emerged as an important player in the regulation of energy metabolism in peripheral tissues. However, its role in the hypothalamus...

Adiposity Browning Energy balance Hypothalamus Sirtuins brown adipose tissue Adipose Tissue Brown Animals Diet High-Fat Energy Metabolism Female Male Mice Neurons Pro-Opiomelanocortin Sirtuin 3

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Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3.

Violeta Heras, Susana Sangiao-Alvarellos, Maria Manfredi-Lozano, María J Sanchez-Tapia, Francisco Ruiz-Pino, Juan Roa, Maribel Lara-Chica, Rosario Morrugares-Carmona, Nathalie Jouy, Ana P Abreu, Vincent Prevot, Denise Belsham, Maria J Vazquez, Marco A Calzado, Leonor Pinilla, Francisco Gaytan, Ana C Latronico, Ursula B Kaiser, Juan M Castellano, Manuel Tena-Sempere

Jan 20, 2020

Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; yet, the molecular...

Animals Binding Sites Cell Line Female Gene Expression Regulation Developmental Hypothalamus Male MicroRNAs Rats Sequence Analysis DNA Sexual Maturation Ubiquitin-Protein Ligases

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Optimizing the use of a sensor resource for opponent polarization coding

FJH Heras, SB Laughlin

Feb 02, 2017

dorsal rim photon noise fly jnd photoreceptor length Vision polarized light efficient design discriminable polarization angles transduction units

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Cover Image for Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development

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Apobec1-Mediated RNA Editing in Monocytes Contributes to Genetic Heterogeneity and Modulates Monocyte Activity and Development

Violeta Rayón Estrada

Jan 01, 0001

Post-transcriptional modifications such as alternative splicing have been shown to add to the complexity needed to compensate for the relatively low number of genes found in higher organisms. Many other modifications recently...

Life Sciences

Published by: Rockefeller University

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Powerfully solvable and powerfully simple groups

Iker de las Heras, Gunnar Traustason

Aug 31, 2021

We introduce the notion of a powerfully solvable group. These are powerful groups possessing an abelian series of a special kind. These groups include in particular the class of powerfully nilpotent groups. We will also see...

/dk/atira/pure/subjectarea/asjc/2600/2602 name=Algebra and Number Theory

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Deconstructing Organizational Resilience

Dilek Yilmaz Börekçi, Yasin Rofcanin, Mireia Las Heras, Aykut Berber

May 31, 2021

This study extends previous research on organizational resilience by focusing on its relational resilience dimension and integrating with its operational resilience dimension. Our main goal is to understand relational...

operational resilience organizational resilience relational resilience /dk/atira/pure/subjectarea/asjc/1400/1403 name=Business and International Management /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management

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Deconstructing Organizational Resilience

Dilek Yilmaz Börekçi, Yasin Rofcanin, Mireia Las Heras, Aykut Berber

May 31, 2021

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Strategic Renewal at Home and Work

Siqi Wang, Can Ererdi, Yasin Rofcanin, Mireia Las Heras

Aug 01, 2022

In this weekly diary study, we integrated research on strategic renewal and the Work-Home Resources model (i.e., W-HR model) to explore the associations between strategic renewal at home and strategic renewal at work domains...

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Understanding flexibility i-deals

Can Ererdi, Siqi Wang, Yasin Rofcanin, Mireia Las Heras

May 15, 2023

Purpose

The goal of this study is to explore the consequences of flexibility i-deals in work and non-work domains of employees.
Design/methodology/approach

A matched supervisor–subordinate sample...

Flexibility i-deals Performance motivation turnover intentions Work–family conflict /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management

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A bibliometric analysis of psychological contract research

Sanat Kozhakhmet, Yasin Rofcanin, Assylbek Nurgabdeshov, Mireia Las Heras

Jul 04, 2023

Purpose: The purpose of this paper is to review and analyse the literature on psychological contract (PC) phenomena to date as well as give future research directions in this research area. Design/methodology/approach: The...

Bibliometric analysis Psychological Contract Scientific visualization /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation

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Seeing eye to eye on family supportive supervisor behaviors

Elise Marescaux, Yasin Rofcanin, Mireia Las Heras

Jul 01, 2018

In a context characterized by harsh competition, time pressure and increasing turnover of employees, a key issue for managers and organizations is to help employees in their juggling between work and family. As such, family...

/dk/atira/pure/subjectarea/asjc/1400/1404 name=Management Information Systems /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/subjectarea/asjc/1400/1410 name=Industrial relations /dk/atira/pure/sustainabledevelopmentgoals/industry_innovation_and_infrastructure name=SDG 9 - Industry, Innovation, and Infrastructure

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Sharing is caring

Jakob Stollberger, Mireia Las Heras, Yasin Rofcanin

Dec 31, 2022

Integrating the work-family facilitation model with the integrated model of human energy, we advance a process perspective involving both members of a couple (i.e., actor and partner). We examine the effects of coworker...

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Genetics of Gland-in-situ or Hypoplastic Congenital Hypothyroidism in Macedonia.

Nikolina Zdraveska, Mirjana Kocova, Adeline K Nicholas, Violeta Anastasovska, Nadia Schoenmakers

May 27, 2020

congenital hypothyroidism dyshormonogenesis Genes Goiter Iodine screening thyroid hypoplasia Child Child Preschool congenital hypothyroidism High-Throughput Nucleotide Sequencing Humans Infant Infant Newborn Mutation PAX8 Transcription Factor Phenotype Receptors Thyrotropin Republic of North Macedonia Thyroid Dysgenesis

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Heteropolynuclear Pt(II)–M(I) clusters with a C∧N∧C biscyclometalated ligand

Sara Fuertes, Christopher H. Woodall, Paul R. Raithby, Violeta Sicilia

Jun 11, 2012

The mononuclear complex [(EtO2C-CNC)Pt(dmpyz)] (1) (dmpyz = 2,5-dimethylpyrazine) has been synthesized by reaction of [(EtO2C-CNC)Pt(dmso)] (A) with dmpyz in a 1:1 molar ratio in dichloromethane. Complex 1 is the precursor for...

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Ion-Pair-Directed Borylation of Aromatic Phosphonium Salts.

Bernadette Lee, Madalina T Mihai, Violeta Stojalnikova, Robert J Phipps

May 22, 2019

Control of positional selectivity in C-H activation reactions remains a challenge for synthetic chemists. Noncovalent catalysis has the potential to be a powerful strategy to address this challenge. As a part of our ongoing...

0306 Physical Chemistry (incl. Structural)

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Genetics of Gland- in-situ or Hypoplastic Congenital Hypothyroidism in Macedonia

Nikolina Zdraveska, Mirjana Kocova, Adeline K. Nicholas, Violeta Anastasovska, Nadia Schoenmakers

Jul 28, 2020

Neonatal screening in Macedonia detects congenital hypothyroidism (CH) with an incidence of 1 in 1,585, and more than 50% of cases exhibit a normally located gland-in-situ (GIS). Monogenic mutations causing dyshormonogenesis may...

Endocrinology congenital hypothyroidism dyshormonogenesis Goiter thyroid hypoplasia Iodine Genes screening

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Seeing eye to eye on family supportive supervisor behaviors

Elise Marescaux, Yasin Rofcanin, Mireia Las Heras

Jul 01, 2018

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Family supportive supervisor behaviors and organizational culture

Yasin Rofcanin, Mireia Las Heras, Arnold B Bakker

Apr 01, 2017

Informed by social information processing (SIP) theory, in this study, we assessed the associations among family supportive supervisor behaviors (FSSBs) as perceived by subordinates, subordinate work engagement, and...

Family supportive organizational culture Family supportive supervisor behaviors Social information processing (SIP) theory Work Engagement Work Performance /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/2700/2739 name=Public Health, Environmental and Occupational Health /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being

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Sharing is caring

Jakob Stollberger, Mireia Las Heras, Yasin Rofcanin

Dec 31, 2022

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Optimal searching behaviour generated intrinsically by the central pattern generator for locomotion.

David W Sims, Nicolas E Humphries, Nan Hu, Violeta Medan, Jimena Berni

Jan 20, 2020

Efficient searching for resources such as food by animals is key to their survival. It has been proposed that diverse animals from insects to sharks and humans adopt searching patterns that resemble a simple Lévy random walk...

D. melanogaster central pattern generator Ecology Exploration levy walk Locomotion neuroscience Animals Apoptosis Appetitive Behavior Brain Central pattern generators Cues Drosophila Proteins Drosophila melanogaster Dynamins Exploratory Behavior Feeding Behavior Larva Locomotion Probability Temperature

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Serving followers and family? A trickle-down model of how servant leadership shapes employee work performance

Jakob Stollberger, Mireia Las Heras, Yasin Rofcanin, Maria Jose Bosch Kreis

Jun 01, 2019

Previous studies have identified servant leadership as an important driver of organizational effectiveness. However, so far little research attention has been given to whether servant leadership displayed by leaders across an...

Family motivation Prosocial motivation Servant leadership Trickle-down model Work Performance /dk/atira/pure/subjectarea/asjc/3300/3304 name=Education /dk/atira/pure/subjectarea/asjc/3200/3202 name=Applied Psychology /dk/atira/pure/subjectarea/asjc/1400/1407 name=Organizational Behavior and Human Resource Management /dk/atira/pure/subjectarea/asjc/3300/3319 name=Life-span and Life-course Studies

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Heteropolynuclear Pt(II)–M(I) clusters with a C∧N∧C biscyclometalated ligand

Sara Fuertes, Christopher H. Woodall, Paul R. Raithby, Violeta Sicilia

Jun 11, 2012

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A Closer Look at the Positive Crossover between Supervisors and Subordinates The Role of Home and Work Engagement

Yasin Rofcanin, Mireia Las Heras, Maria Jose Bosch, Geoff Wood, Farooq Mughal

Nov 01, 2019

How can we explain the crossover of positive experiences from supervisors to their subordinates? Drawing on crossover research and social learning theory (SLT), our main goal in this study is to explore mechanisms and...

HR differentiation fairness co-workers justice Approach avoidance home engagement crossover POS Work Engagement FSSB /dk/atira/pure/subjectarea/asjc/3300/3300 name=General Social Sciences /dk/atira/pure/subjectarea/asjc/1200/1201 name=Arts and Humanities (miscellaneous) /dk/atira/pure/subjectarea/asjc/1400/1405 name=Management of Technology and Innovation /dk/atira/pure/subjectarea/asjc/1400/1408 name=Strategy and Management

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