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Anthropometric cut-offs to identify hyperglycemia in an Afro-Caribbean population
Introduction: Body mass index (BMI) and waist circumference (WC) cut-offs associated with hyperglycemia may differ by ethnicity. We investigated the optimal BMI and WC cut-offs for identifying hyperglycemia in the predominantly...
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Changes in waist circumference and risk of all-cause and CVD mortality
Abstract: Background: Measures of abdominal adiposity are strongly associated with all-cause mortality and cardiovascular disease (CVD). However, data are limited and conflicting regarding the consequences of changes in body fat...
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Waist circumference and a body shape index and prostate cancer risk and mortality.
We recently found a negative association between body mass index (BMI) and the risk of localised prostate cancer (PCa), no association with advanced PCa, and a positive association with PCa-specific mortality. In a 15%...
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Simultaneous two-phase flame velocity measurement using laser-induced incandescence particle image velocimetry (LII-PIV)
In a previous study we demonstrated a novel two-phase PIV technique based on the laser-induced incandescence (LII) signal from black submicron tungsten carbide particles (WC), which achieved velocity measurement for both...
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Germ cell specification and pluripotency in mammals
Germ cells are unique cell types that generate a totipotent zygote upon fertilization, giving rise to the next generation in mammals and many other multicellular organisms. How germ cells acquire this ability has been of...
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Specification and epigenetic programming of the human germ line.
Primordial germ cells (PGCs), the precursors of sperm and eggs, are established in perigastrulation-stage embryos in mammals. Signals from extra-embryonic tissues induce a unique gene regulatory network in germline-competent...
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Reactive intermediates for interactome mapping.
The interactions of biomolecules underpin all cellular processes, and the understanding of their dynamic interplay can lead to significant advances in the treatment of disease through the identification of novel therapeutic...
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Synchronous and opponent thermosensors use flexible cross-inhibition to orchestrate thermal homeostasis.
Body temperature homeostasis is essential and reliant upon the integration of outputs from multiple classes of cooling- and warming-responsive cells. The computations that integrate these outputs are not understood. Here, we...
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