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Gonadotrophin-independent Precocious Puberty Secondary to an Estrogen Secreting Adrenal Tumor.
Xanthippi Tseretopoulou, Matthew J Murray, Jackie Buck, C Elizabeth Hook, Claire Jackson, Vasilis Kosmoliaptsis, Jacqueline Hughes, Samantha Gorman, Rachel M Williams
Apr 16, 2021
BACKGROUND: Adrenal masses are rare in children and most commonly present with clinical features of virilization in the absence of activation of the pituitary axis-gonadotrophin-independent precocious puberty. OBSERVATIONS: We...
Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.
Chun-Fui Lai, Koen D Flach, Xanthippi Alexi, Stephen P Fox, Silvia Ottaviani, Paul TR Thiruchelvam, Fiona J Kyle, Ross S Thomas, Rosalind Launchbury, Hui Hua, Holly B Callaghan, Jason S Carroll, R Charles Coombes, Wilbert Zwart, Laki Buluwela, Simak Ali
May 01, 2019
Oestrogen receptor α (ERα) is a nuclear receptor that is the driving transcription factor expressed in the majority of breast cancers. Recent studies have demonstrated that the liver receptor homolog-1 (LRH-1), another nuclear...