Search
Results: 63
Plastin increases cortical connectivity to facilitate robust polarization and timely cytokinesis.
Wei Yung Ding, Hui Ting Ong, Yusuke Hara, Jantana Wongsantichon, Yusuke Toyama, Robert C Robinson, François Nédélec, Ronen Zaidel-Bar
Jul 29, 2020
The cell cortex is essential to maintain animal cell shape, and contractile forces generated within it by nonmuscle myosin II (NMY-2) drive cellular morphogenetic processes such as cytokinesis. The role of actin cross-linking...
Functional comparison of the mouse DC-SIGN, SIGNR1, SIGNR3 and Langerin, C-type lectins
The mouse (m) DC-SIGN family consists of several homologous type II transmembrane proteins located in close proximity on chromosome 8 and having a single carboxyl terminal carbohydrate recognition domain. We first used...
Published by: Rockefeller University
A 1-hydroxy-2,3,1-benzodiazaborine-containing π-conjugated system
Our interest in the functionalization of [sbnd]OH-substituted azaborines prompted us to synthesize a 1-hydroxy-2,3,1-benzodiazaborine conjugated with 1,8-naphthalimide 1. Its fluorescence was dramatically affected by the...
Normative design using inductive learning
In this paper we propose a use-case-driven iterative design methodology for normative frameworks, also called virtual institutions, which are used to govern open systems. Our computational model represents the normative...
Normative design using inductive learning
In this paper we propose a use-case-driven iterative design methodology for normative frameworks, also called virtual institutions, which are used to govern open systems. Our computational model represents the normative...
MADGAN
Changhee Han, Leonardo Rundo, Kohei Murao, Tomoyuki Noguchi, Yuki Shimahara, Zoltán Ádám Milacski, Saori Koshino, Evis Sala, Hideki Nakayama, Shin’ichi Satoh
Apr 26, 2021
Abstract: Background: Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical...
Integrated omics unveil the secondary metabolic landscape of a basal dinoflagellate
Girish Beedessee, Takaaki Kubota, Asuka Arimoto, Koki Nishitsuji, Ross F. Waller, Kanako Hisata, Shinichi Yamasaki, Noriyuki Satoh, Jun’ichi Kobayashi, Eiichi Shoguchi
Oct 13, 2020
Abstract: Background: Some dinoflagellates cause harmful algal blooms, releasing toxic secondary metabolites, to the detriment of marine ecosystems and human health. Our understanding of dinoflagellate toxin biosynthesis has...
MADGAN
Changhee Han, Leonardo Rundo, Kohei Murao, Tomoyuki Noguchi, Yuki Shimahara, Zoltán Ádám Milacski, Saori Koshino, Evis Sala, Hideki Nakayama, Shin'ichi Satoh
Jul 12, 2021
BACKGROUND: Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to...
Contribution of <i>sox9b</i> to pigment cell formation in medaka fish
Yuri Tsunogai, Motohiro Miyadai, Yusuke Nagao, Keisuke Sugiwaka, Robert N Kelsh, Masahiko Hibi, Hisashi Hashimoto
Dec 31, 2021
SoxE-type transcription factors, Sox10 and Sox9, are key regulators of the development of neural crest cells. Sox10 specifies pigment cell, glial, and neuronal lineages, whereas Sox9 is reportedly closely associated with...
A 1-hydroxy-2,3,1-benzodiazaborine-containing π-conjugated system
Our interest in the functionalization of [sbnd]OH-substituted azaborines prompted us to synthesize a 1-hydroxy-2,3,1-benzodiazaborine conjugated with 1,8-naphthalimide 1. Its fluorescence was dramatically affected by the...
Integrated omics unveil the secondary metabolic landscape of a basal dinoflagellate
Girish Beedessee, Takaaki Kubota, Asuka Arimoto, Koki Nishitsuji, Ross F. Waller, Kanako Hisata, Shinichi Yamasaki, Noriyuki Satoh, Jun’ichi Kobayashi, Eiichi Shoguchi
Oct 13, 2021
Abstract: Background: Some dinoflagellates cause harmful algal blooms, releasing toxic secondary metabolites, to the detriment of marine ecosystems and human health. Our understanding of dinoflagellate toxin biosynthesis has...
Memory-specific correlated neuronal activity in higher-order auditory regions of a parrot.
Ryohei Satoh, Hiroko Eda-Fujiwara, Aiko Watanabe, Yasuharu Okamoto, Takenori Miyamoto, Matthijs A Zandbergen, Johan J Bolhuis
Jan 15, 2021
Integrated omics unveil the secondary metabolic landscape of a basal dinoflagellate.
Girish Beedessee, Takaaki Kubota, Asuka Arimoto, Koki Nishitsuji, Ross F Waller, Kanako Hisata, Shinichi Yamasaki, Noriyuki Satoh, Jun'ichi Kobayashi, Eiichi Shoguchi
Dec 14, 2020
BACKGROUND: Some dinoflagellates cause harmful algal blooms, releasing toxic secondary metabolites, to the detriment of marine ecosystems and human health. Our understanding of dinoflagellate toxin biosynthesis has been hampered...
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.
Ryotaro Nishi, Paul WG Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Tom L Blundell, Benedikt M Kessler
Feb 14, 2019
Automatic Detection of Microaneurysms in Fundus Images
Early detection and treatment of diabetic retinopathy can delay blindness and improve quality of life for diabetic patients. It is difficult to detect early symptoms of diabetic retinopathy, which is presented by few...
Systems & Software Design Computer Science and Information Technology Systems and Software Engineering
Published by: IGI Global Scientific Publishing
Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.
Takahiro K Fujiwara, Kokoro Iwasawa, Ziya Kalay, Taka A Tsunoyama, Yusuke Watanabe, Yasuhiro M Umemura, Hideji Murakoshi, Kenichi GN Suzuki, Yuri L Nemoto, Nobuhiro Morone, Akihiro Kusumi
May 28, 2019
The mechanisms by which the diffusion rate in the plasma membrane (PM) is regulated remain unresolved, despite their importance in spatially regulating the reaction rates in the PM. Proposed models include entrapment in...
Towards prognostic functional brain biomarkers for cervical myelopathy
Shota Takenaka, Shigeyuki Kan, Ben Seymour, Takahiro Makino, Yusuke Sakai, Junichi Kushioka, Hisashi Tanaka, Yoshiyuki Watanabe, Masahiko Shibata, Hideki Yoshikawa, Takashi Kaito
Jul 17, 2020
Abstract: Recently, there has been increasing interest in strategies to predict neurological recovery in cervical myelopathy (CM) based on clinical images of the cervical spine. In this study, we aimed to explore potential...
Towards prognostic functional brain biomarkers for cervical myelopathy
Shota Takenaka, Shigeyuki Kan, Ben Seymour, Takahiro Makino, Yusuke Sakai, Junichi Kushioka, Hisashi Tanaka, Yoshiyuki Watanabe, Masahiko Shibata, Hideki Yoshikawa, Takashi Kaito
Aug 02, 2019
Recently, there has been increasing interest in strategies to predict neurological recovery in cervical myelopathy (CM) based on clinical images of the cervical spine. In this study, we aimed to explore potential preoperative...
Contribution of <i>sox9b</i> to pigment cell formation in medaka fish
Yuri Tsunogai, Motohiro Miyadai, Yusuke Nagao, Keisuke Sugiwaka, Robert N Kelsh, Masahiko Hibi, Hisashi Hashimoto
Dec 31, 2021
SoxE-type transcription factors, Sox10 and Sox9, are key regulators of the development of neural crest cells. Sox10 specifies pigment cell, glial, and neuronal lineages, whereas Sox9 is reportedly closely associated with...
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Alisa F Zyryanova, Félix Weis, Alexandre Faille, Akeel Abo Alard, Ana Crespillo-Casado, Yusuke Sekine, Heather P Harding, Felicity Allen, Leopold Parts, Christophe Fromont, Peter M Fischer, Alan J Warren, David Ron
Apr 04, 2018
Differential interaction with TREM2 modulates microglial uptake of modified Aβ species.
Pranav Joshi, Florian Riffel, Kanayo Satoh, Masahiro Enomoto, Seema Qamar, Hannah Scheiblich, Nàdia Villacampa, Sathish Kumar, Sandra Theil, Samira Parhizkar, Christian Haass, Michael T Heneka, Paul E Fraser, Peter St George-Hyslop, Jochen Walter
Aug 26, 2021
Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis
Shinya Hayami, Masanori Yoshimatsu, Abhimanyu Veerakumarasivam, Motoko Unoki, Yukiko Iwai, Tatsuhiko Tsunoda, Helen I Field, John D Kelly, David E Neal, Hiroki Yamaue, Bruce AJ Ponder, Yusuke Nakamura, Ryuji Hamamoto
Sep 12, 2011
Cell Line Tumor Cell Proliferation E2F1 Transcription Factor E2F2 Transcription Factor Female Gene Expression Regulation Neoplastic Humans Jumonji Domain-Containing Histone Demethylases Male Nuclear Proteins Oligonucleotide Array Sequence Analysis Precancerous Conditions Repressor Proteins Reproducibility of Results Retinoblastoma Protein Signal Transduction Tissue Array Analysis Up-Regulation
State-of-the-art global models underestimate impacts from climate extremes.
Jacob Schewe, Simon N Gosling, Christopher Reyer, Fang Zhao, Philippe Ciais, Joshua Elliott, Louis Francois, Veronika Huber, Heike K Lotze, Sonia I Seneviratne, Michelle TH van Vliet, Robert Vautard, Yoshihide Wada, Lutz Breuer, Matthias Büchner, David A Carozza, Jinfeng Chang, Marta Coll, Delphine Deryng, Allard de Wit, Tyler D Eddy, Christian Folberth, Katja Frieler, Andrew D Friend, Dieter Gerten, Lukas Gudmundsson, Naota Hanasaki, Akihiko Ito, Nikolay Khabarov, Hyungjun Kim, Peter Lawrence, Catherine Morfopoulos, Christoph Müller, Hannes Müller Schmied, René Orth, Sebastian Ostberg, Yadu Pokhrel, Thomas AM Pugh, Gen Sakurai, Yusuke Satoh, Erwin Schmid, Tobias Stacke, Jeroen Steenbeek, Jörg Steinkamp, Qiuhong Tang, Hanqin Tian, Derek P Tittensor, Jan Volkholz, Xuhui Wang, Lila Warszawski
Mar 15, 2019
Global impact models represent process-level understanding of how natural and human systems may be affected by climate change. Their projections are used in integrated assessments of climate change. Here we test, for the first...
A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis
Tadasuke Tsukiyama, Juqi Zou, Jihoon Kim, Shohei Ogamino, Yuki Shino, Takamasa Masuda, Alessandra Merenda, Masaki Matsumoto, Yoichiro Fujioka, Tomonori Hirose, Sayuri Terai, Hidehisa Takahashi, Tohru Ishitani, Keiichi I. Nakayama, Yusuke Ohba, Bon-Kyoung Koo, Shigetsugu Hatakeyama
Sep 15, 2020
|
|< |
< |
1 |