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Results: 4918
Molecular Mechanism of Z α1-Antitrypsin Deficiency.
Xin Huang, Ying Zheng, Fei Zhang, Zhenquan Wei, Yugang Wang, Robin W Carrell, Randy J Read, Guo-Qiang Chen, Aiwu Zhou
Feb 12, 2020
The Z mutation (E342K) of α1-antitrypsin (α1-AT), carried by 4% of Northern Europeans, predisposes to early onset of emphysema due to decreased functional α1-AT in the lung and to liver cirrhosis due to accumulation of polymers...
Performing Locality and Identity
Lijun Zhang
Sep 21, 2016
The paper examines the fusion of narratives, time, space, and personal identity through ethnographic study of rickshaw driver’s performance in the context of “Hutong tour” as a form of urban tourism in Beijing, a cosmopolitan...
Published by: Association of Cambridge Studies
AGN-host connection at 0.5 <z <2.5
Tao Wang, D. Elbaz, D. M. Alexander, J. M. Gabor, S. Juneau, C. Schreiber, X. Z. Zheng, S. Wuyts, E. Daddi, X. W. Shu, G. W. Fang, Q. S. Gu
May 01, 2017
We explore the dependence of the incidence of moderate-luminosity (L0.5-8 keV = 1041.9-43.7 erg s-1) active galactic nuclei (AGNs) and the distribution of their accretion rates on host color...
AGN-host connection at 0.5 <z <2.5
Tao Wang, D. Elbaz, D. M. Alexander, J. M. Gabor, S. Juneau, C. Schreiber, X. Z. Zheng, S. Wuyts, E. Daddi, X. W. Shu, G. W. Fang, Q. S. Gu
May 01, 2017
We explore the dependence of the incidence of moderate-luminosity (L0.5-8 keV = 1041.9-43.7 erg s-1) active galactic nuclei (AGNs) and the distribution of their accretion rates on host color...
Searching for New Z-DNA/Z-RNA Binding Proteins Based on Structural Similarity to Experimentally Validated Zα Domain.
Martin Bartas, Kristyna Slychko, Václav Brázda, Jiří Červeň, Christopher A Beaudoin, Tom L Blundell, Petr Pečinka
Feb 20, 2022
Z-DNA and Z-RNA are functionally important left-handed structures of nucleic acids, which play a significant role in several molecular and biological processes including DNA replication, gene expression regulation and viral...
Z-DNA Z-RNA Zα domain Bioinformatics Protein Binding Amino Acid Sequence Binding Sites DNA Z-Form DNA-Binding Proteins Models Molecular Molecular Docking Simulation Molecular Dynamics Simulation Nucleic Acid Conformation Protein Binding Protein Conformation Protein Interaction Domains and Motifs RNA RNA-Binding Proteins Structure-Activity Relationship
The Evolution of the Tully-Fisher Relation between z ∼ 2.3 and z ∼ 0.9 with KMOS<sup>3D</sup>
H. Übler, N. M. Förster Schreiber, R. Genzel, E. Wisnioski, S. Wuyts, P. Lang, T. Naab, A. Burkert, P. G. van Dokkum, L. J. Tacconi, D. J. Wilman, M. Fossati, J. T. Mendel, A. Beifiori, Sirio Belli, R. Bender, G. B. Brammer, J Chan, R Davies, M. Fabricius, A. Galametz, D. Lutz, I. G. Momcheva, E. J. Nelson, R. P. Saglia, S. Seitz, K. I Tadaki
Jun 20, 2017
We investigate the stellar mass and baryonic mass Tully-Fisher relations (TFRs) of massive star-forming disk galaxies at redshift z ∼ 2.3 and z ∼ 0.9 as part of the KMOS3D integral field spectroscopy survey. Our spatially...
The Uniformisation of the Equation $$z^w=w^z$$
Abstract The positive solutions of the equation $$x^y = y^x$$
AF Beardon
Mar 29, 2022
The Evolution of the Tully-Fisher Relation between z ∼ 2.3 and z ∼ 0.9 with KMOS<sup>3D</sup>
H. Übler, N. M. Förster Schreiber, R. Genzel, E. Wisnioski, S. Wuyts, P. Lang, T. Naab, A. Burkert, P. G. van Dokkum, L. J. Tacconi, D. J. Wilman, M. Fossati, J. T. Mendel, A. Beifiori, Sirio Belli, R. Bender, G. B. Brammer, J Chan, R Davies, M. Fabricius, A. Galametz, D. Lutz, I. G. Momcheva, E. J. Nelson, R. P. Saglia, S. Seitz, K. I Tadaki
Jun 20, 2017
We investigate the stellar mass and baryonic mass Tully-Fisher relations (TFRs) of massive star-forming disk galaxies at redshift z ∼ 2.3 and z ∼ 0.9 as part of the KMOS3D integral field spectroscopy survey. Our spatially...
Precision measurement of forward Z boson production in proton-proton collisions at √s = 13 TeV
R Aaij, ASW Abdelmotteleb, C Abellán Beteta, F Abudinén, T Ackernley, B Adeva, M Adinolfi, H Afsharnia, C Agapopoulou, CA Aidala, S Aiola, Z Ajaltouni, S Akar, J Albrecht, F Alessio, M Alexander, A Alfonso Albero, Z Aliouche, G Alkhazov, P Alvarez Cartelle, S Amato, JL Amey, Y Amhis, L An, L Anderlini, M Andersson, A Andreianov, M Andreotti, F Archilli, A Artamonov, M Artuso, K Arzymatov, E Aslanides, M Atzeni, B Audurier, S Bachmann, M Bachmayer, JJ Back, P Baladron Rodriguez, V Balagura, W Baldini, J Baptista de Souza Leite, M Barbetti, RJ Barlow, S Barsuk, W Barter, M Bartolini, F Baryshnikov, JM Basels, S Bashir, G Bassi, B Batsukh, A Battig, A Bay, A Beck, M Becker, F Bedeschi, I Bediaga, A Beiter, V Belavin, S Belin, V Bellee, K Belous, I Belov, I Belyaev, G Bencivenni, E Ben-Haim, A Berezhnoy, R Bernet, D Berninghoff, HC Bernstein, C Bertella, A Bertolin, C Betancourt, F Betti, I Bezshyiko, S Bhasin, J Bhom, L Bian, MS Bieker, NV Biesuz, S Bifani, P Billoir, A Biolchini, M Birch, FCR Bishop, A Bitadze, A Bizzeti, M Bjørn, MP Blago, T Blake, F Blanc, S Blusk, D Bobulska, JA Boelhauve, O Boente Garcia, T Boettcher, A Boldyrev, A Bondar, N Bondar
Jul 06, 2022
A precision measurement of the $Z$ boson production cross-section at
$\sqrt{s} = 13$ TeV in the forward region is presented, using $pp$ collision
data collected by the LHCb detector, corresponding to an integrated luminosity
of...
Identification of high risk clinical and imaging features for intracranial artery dissection using high-resolution cardiovascular magnetic resonance.
Zhang Shi, Xia Tian, Bing Tian, Zakaria Meddings, Xuefeng Zhang, Jing Li, David Saloner, Qi Liu, Zhongzhao Teng, Jianping Lu
Jul 28, 2021
Background
Intracranial artery dissection (IAD) often causes headache and cerebral vascular ischemic events. The imaging characteristics of IAD remain unclear. This study aims to characterize the appearance of culprit...
Identification of high risk clinical and imaging features for intracranial artery dissection using high-resolution cardiovascular magnetic resonance
Zhang Shi, Xia Tian, Bing Tian, Zakaria Meddings, Xuefeng Zhang, Jing Li, David Saloner, Qi Liu, Zhongzhao Teng, Jianping Lu
Jun 14, 2021
Abstract: Background: Intracranial artery dissection (IAD) often causes headache and cerebral vascular ischemic events. The imaging characteristics of IAD remain unclear. This study aims to characterize the appearance of culprit...
Major merging history in CANDELS. I. Evolution of the incidence of massive galaxy–galaxy pairs from z = 3 to z ∼ 0
Kameswara Bharadwaj Mantha, Daniel H. McIntosh, Ryan Brennan, Henry C. Ferguson, Dritan Kodra, Jeffrey A. Newman, Marc Rafelski, Rachel S. Somerville, Christopher J. Conselice, Joshua S Cook, Nimish P. Hathi, David C. Koo, Jennifer M. Lotz, Brooke D Simmons, Amber N. Straughn, Gregory F Snyder, Stijn Wuyts, Eric F. Bell, Avishai Dekel, Jeyhan S. Kartaltepe, Dale D. Kocevski, Anton M. Koekemoer, Seong Kook Lee, Ray A. Lucas, Camilla Pacifici, Michael A Peth, Guillermo Barro, Tomas Dahlen, Steven L. Finkelstein, Adriano Fontana, Audrey Galametz, Norman A. Grogin, Yicheng Guo, Bahram Mobasher, Hooshang Nayyeri, Pablo G. Pérez-González, Janine Pforr, Paola Santini, Mauro Stefanon, Tommy Wiklind
Apr 01, 2018
The rate of major galaxy–galaxy merging is theoretically predicted to steadily increase with redshift during the peak epoch of massive galaxy development (1 ≤ z ≤ 3). We use close-pair statistics to objectively study the...
Gamification and Gen Z in Higher Education
Research has found that the new-age learner, Gen Z, is different from his/ her predecessors and hence educators need new age pedagogical interventions to cater to this group of learners. With a change in the way the new age...
Published by: IGI Global Scientific Publishing
Identification of high risk clinical and imaging features for intracranial artery dissection using high-resolution cardiovascular magnetic resonance.
Zhang Shi, Xia Tian, Bing Tian, Zakaria Meddings, Xuefeng Zhang, Jing Li, David Saloner, Qi Liu, Zhongzhao Teng, Jianping Lu
Jul 21, 2021
BACKGROUND: Intracranial artery dissection (IAD) often causes headache and cerebral vascular ischemic events. The imaging characteristics of IAD remain unclear. This study aims to characterize the appearance of culprit and...
Performance Optimization of Big Data Transfer in High-performance Networks: A ReinforcementLearning Approach
Daqing Yun
Jan 01, 0001
Choosing optimal parameter values for big data transfer in HPNs
Published by: Harrisburg University of Science and Technology
A Study of Tsunami UDP Protocol
Daqing Yun
Jan 01, 0001
Modeling and Optimizing Tsunami UDP Protocol
Published by: Harrisburg University of Science and Technology
Bandwidth Scheduling in High-performance Networks (Tentative)
Daqing Yun
Jan 01, 0001
Formulate bandwidth scheduling problems with various objects; prove complexities of these problems; design and evaluate proposed heuristics using simulations
Published by: Harrisburg University of Science and Technology
Machine Learning in High-performance Networking
Daqing Yun
Jan 01, 0001
Apply machine learning methods to improve high-performance networking
Published by: Harrisburg University of Science and Technology
Performance Optimization of Big Data Workflows in Distributed Environments
Daqing Yun
Jan 01, 0001
Formulate performance optimization problems of big data workflows with various objects; prove complexities of these problems; design and evaluate proposed heuristics using simulations
Published by: Harrisburg University of Science and Technology
Major merging history in CANDELS. I. Evolution of the incidence of massive galaxy–galaxy pairs from z = 3 to z ∼ 0
Kameswara Bharadwaj Mantha, Daniel H. McIntosh, Ryan Brennan, Henry C. Ferguson, Dritan Kodra, Jeffrey A. Newman, Marc Rafelski, Rachel S. Somerville, Christopher J. Conselice, Joshua S Cook, Nimish P. Hathi, David C. Koo, Jennifer M. Lotz, Brooke D Simmons, Amber N. Straughn, Gregory F Snyder, Stijn Wuyts, Eric F. Bell, Avishai Dekel, Jeyhan S. Kartaltepe, Dale D. Kocevski, Anton M. Koekemoer, Seong Kook Lee, Ray A. Lucas, Camilla Pacifici, Michael A Peth, Guillermo Barro, Tomas Dahlen, Steven L. Finkelstein, Adriano Fontana, Audrey Galametz, Norman A. Grogin, Yicheng Guo, Bahram Mobasher, Hooshang Nayyeri, Pablo G. Pérez-González, Janine Pforr, Paola Santini, Mauro Stefanon, Tommy Wiklind
Apr 01, 2018
The rate of major galaxy–galaxy merging is theoretically predicted to steadily increase with redshift during the peak epoch of massive galaxy development (1 ≤ z ≤ 3). We use close-pair statistics to objectively study the...
Discovery of Protoclusters at z∼3.7 and 4.9
Jun Toshikawa, Matthew A. Malkan, Nobunari Kashikawa, Roderik Overzier, Hisakazu Uchiyama, Kazuaki Ota, Shogo Ishikawa, Kei Ito
Jan 13, 2020
We have carried out follow-up spectroscopy on three overdense regions of g- and r-dropout galaxies in the Canada–France–Hawaii Telescope Legacy Survey Deep Fields, finding two new protoclusters at z = 4.898 and 3.721 and a...
HST/WFC3 grism observations of z similar to 1 clusters
J Matharu, A Muzzin, GB Brammer, RFJ van der Burg, MW Auger, PC Hewett, A van der Wel, P van Dokkum, M Balogh, JCC Chan, R Demarco, D Marchesini, EJ Nelson, A Noble, G Wilson, HKC Yee
Apr 26, 2019
Minor mergers are thought to be responsible for the size growth of quiescent field galaxies with decreasing redshift. We test this hypothesis using the cluster environment as a laboratory. Satellite galaxies in clusters move at...
A Long Time Ago in a Galaxy Far, Far Away
Steven L. Finkelstein, Micaela B. Bagley, Pablo Arrabal Haro, Mark Dickinson, Henry C. Ferguson, Jeyhan S. Kartaltepe, Casey Papovich, Denis Burgarella, Dale D. Kocevski, Marc Huertas-Company, Kartheik G. Iyer, Anton M. Koekemoer, Rebecca L. Larson, Pablo G. Pérez-González, Caitlin Rose, Sandro Tacchella, Stephen M. Wilkins, Katherine Chworowsky, Aubrey Medrano, Alexa M. Morales, Rachel S. Somerville, L. Y. Aaron Yung, Adriano Fontana, Mauro Giavalisco, Andrea Grazian, Norman A. Grogin, Lisa J. Kewley, Allison Kirkpatrick, Peter Kurczynski, Jennifer M. Lotz, Laura Pentericci, Nor Pirzkal, Swara Ravindranath, Russell E., Jr. Ryan, Jonathan R. Trump, Guang Yang, and The CEERS Team:, Omar Almaini, Ricardo O. Amorín, Marianna Annunziatella, Bren E. Backhaus, Guillermo Barro, Peter Behroozi, Eric F. Bell, Rachana Bhatawdekar, Laura Bisigello, Volker Bromm, Véronique Buat, Fernando Buitrago, Antonello Calabrò, Caitlin M. Casey, Marco Castellano, Óscar A. Chávez Ortiz, Laure Ciesla, Nikko J. Cleri, Seth H. Cohen, Justin W. Cole, Kevin C. Cooke, M. C. Cooper, Asantha R. Cooray, Luca Costantin, Isabella G. Cox, Darren Croton, Emanuele Daddi, Romeel Davé, Alexander de la Vega, Avishai Dekel, David Elbaz, Vicente Estrada-Carpenter, Sandra M. Faber, Vital Fernández, Keely D. Finkelstein, Jonathan Freundlich, Seiji Fujimoto, Ángela García-Argumánez, Jonathan P. Gardner, Eric Gawiser, Carlos Gómez-Guijarro, Yuchen Guo, Kurt Hamblin, Timothy S. Hamilton, Nimish P. Hathi, Benne W. Holwerda, Michaela Hirschmann, Taylor A. Hutchison, Anne E. Jaskot, Saurabh W. Jha, Shardha Jogee, Stéphanie Juneau, Intae Jung, Susan A. Kassin, Aurélien Le Bail, Gene C. K. Leung, Ray A. Lucas, Benjamin Magnelli, Kameswara Bharadwaj Mantha, Jasleen Matharu, Elizabeth J. McGrath, Daniel H. McIntosh, Emiliano Merlin, Bahram Mobasher, Jeffrey A. Newman, David C. Nicholls, Viraj Pandya, Marc Rafelski, Kaila Ronayne, Paola Santini, Lise-Marie Seillé, Ekta A. Shah, Lu Shen, Raymond C. Simons, Gregory F. Snyder, Elizabeth R. Stanway, Amber N. Straughn, Harry I. Teplitz, Brittany N. Vanderhoof, Jesús Vega-Ferrero, Weichen Wang, Benjamin J. Weiner, Christopher N. A. Willmer, Stijn Wuyts, Jorge A. Zavala
Feb 24, 2023
We report the discovery of a candidate galaxy with a photo-z of z ∼ 12 in the first epoch of the James Webb Space Telescope (JWST) Cosmic Evolution Early Release Science Survey. Following conservative selection criteria, we...
Published by: The American Astronomical Society
Development of a small molecule that corrects misfolding and increases secretion of Z α1 -antitrypsin.
David A Lomas, James A Irving, Christopher Arico-Muendel, Svetlana Belyanskaya, Andrew Brewster, Murray Brown, Chun-wa Chung, Hitesh Dave, Alexis Denis, Nerina Dodic, Anthony Dossang, Peter Eddershaw, Diana Klimaszewska, Imran Haq, Duncan S Holmes, Jonathan P Hutchinson, Alistair M Jagger, Toral Jakhria, Emilie Jigorel, John Liddle, Ken Lind, Stefan J Marciniak, Jeff Messer, Margaret Neu, Allison Olszewski, Adriana Ordonez, Riccardo Ronzoni, James Rowedder, Martin Rüdiger, Steve Skinner, Kathrine J Smith, Rebecca Terry, Lionel Trottet, Iain Uings, Steve Wilson, Zhengrong Zhu, Andrew C Pearce
Feb 15, 2021
Severe α1 -antitrypsin deficiency results from the Z allele (Glu342Lys) that causes the accumulation of homopolymers of mutant α1 -antitrypsin within the endoplasmic reticulum of hepatocytes in association with liver disease. We...
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