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Results: 232
Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors.
Antonella Accardo, Filippo Galli, Rosalba Mansi, Luigi Del Pozzo, Michela Aurilio, Anna Morisco, Paola Ringhieri, Alberto Signore, Giancarlo Morelli, Luigi Aloj
Dec 18, 2018
BACKGROUND: Overexpression of the gastrin-releasing peptide receptor (GRP-R) has been documented in several human neoplasms such as breast, prostate, and ovarian cancer. There is growing interest in developing radiolabeled...
Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark.
Alessandro Bertero, Pedro Madrigal, Antonella Galli, Nina C Hubner, Inmaculada Moreno, Deborah Burks, Stephanie Brown, Roger A Pedersen, Daniel Gaffney, Sasha Mendjan, Siim Pauklin, Ludovic Vallier
May 21, 2015
Activin/Nodal DPY30 H3K4me3 NANOG SMAD2/3 hESCs Activins Animals Cell Differentiation Cells Cultured Chromatin Embryo Mammalian Embryonic Stem Cells Epigenesis Genetic Histone Methyltransferases Histone-Lysine N-Methyltransferase Histones Homeodomain Proteins Humans Mice Nanog Homeobox Protein Nodal Protein Signal Transduction Smad2 Protein Smad3 Protein
Synthetic lethality between PAXX and XLF in mammalian development.
Gabriel Balmus, Ana C Barros, Paul WG Wijnhoven, Chloé Lescale, Hélène Lenden Hasse, Katharina Boroviak, Carlos le Sage, Brendan Doe, Anneliese O Speak, Antonella Galli, Matt Jacobsen, Ludovic Deriano, David J Adams, Andrew N Blackford, Stephen P Jackson
Nov 17, 2016
Common and distinct transcriptional signatures of mammalian embryonic lethality
John E. Collins, Richard J. White, Nicole Staudt, Ian M. Sealy, Ian Packham, Neha Wali, Catherine Tudor, Cecilia Mazzeo, Angela Green, Emma Siragher, Edward Ryder, Jacqueline K. White, Irene Papatheodoru, Amy Tang, Anja Füllgrabe, Konstantinos Billis, Stefan H. Geyer, Wolfgang J. Weninger, Antonella Galli, Myriam Hemberger, Derek L. Stemple, Elizabeth Robertson, James C. Smith, Timothy Mohun, David J. Adams, Elisabeth M. Busch-Nentwich
Jun 25, 2020
Abstract: The Deciphering the Mechanisms of Developmental Disorders programme has analysed the morphological and molecular phenotypes of embryonic and perinatal lethal mouse mutant lines in order to investigate the causes of...
Machine Learning on Soccer Player Positions
During the last few years, sports analytics has been growing rapidly. The main usage of this discipline is the prediction of soccer match results, even if it can be applied with interesting results in different areas, such as...
Published by: IGI Global Scientific Publishing
Application of Multiple Regression and Artificial Neural Networks as Tools for Estimating Duration and Life Cycle Cost of Projects
Brian Galli
Jan 01, 2020
Project managers face complex challenges when planning project stages because contract durations and project costs are difficult to predict accurately. The purpose of this study is to investigate statistical tools and concepts...
Published by: IGI Global Scientific Publishing
Practitioner's View on the Future of Economic Decision-Making in Project Management
Brian Galli
Jul 01, 2019
As of now, the best means to plan for the future is project management because it has been proven effective in problem-solving and generating solutions. Few projects entail economic decision-making because of the cost factor...
Published by: IGI Global Scientific Publishing
Placentation defects are highly prevalent in embryonic lethal mouse mutants.
Vicente Perez-Garcia, Elena Fineberg, Robert Wilson, Alexander Murray, Cecilia Icoresi Mazzeo, Catherine Tudor, Arnold Sienerth, Jacqueline K White, Elizabeth Tuck, Edward J Ryder, Diane Gleeson, Emma Siragher, Hannah Wardle-Jones, Nicole Staudt, Neha Wali, John Collins, Stefan Geyer, Elisabeth M Busch-Nentwich, Antonella Galli, James C Smith, Elizabeth Robertson, David J Adams, Wolfgang J Weninger, Timothy Mohun, Myriam Hemberger
Jun 20, 2018
Large-scale phenotyping efforts have demonstrated that approximately 25-30% of mouse gene knockouts cause intrauterine lethality. Analysis of these mutants has largely focused on the embryo and not the placenta, despite the...
Continuous Technological Improvement Using Systems Engineering Principles to Achieve Sustainability
Brian Galli
Jul 01, 2020
The design of a continuous plan would benefit society, as seen in systems engineering. To understand complex systems and to uphold the principles of stability, systems engineering has shown that it is a discipline of great...
Published by: IGI Global Scientific Publishing
Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-body energy expenditure.
Kifayathullah Liakath-Ali, Valerie E Vancollie, Christopher J Lelliott, Anneliese O Speak, David Lafont, Hayley J Protheroe, Camilla Ingvorsen, Antonella Galli, Angela Green, Diane Gleeson, Ed Ryder, Leanne Glover, Gema Vizcay-Barrena, Natasha A Karp, Mark J Arends, Thomas Brenn, Sarah Spiegel, David J Adams, Fiona M Watt, Louise van der Weyden
Feb 18, 2021
The epidermis is the outermost layer of skin that acts as a barrier to protect the body from the external environment and to control water and heat loss. This barrier function is established through the multistage...
ceramidase Energy homeostasis Sebaceous Glands skin homeostasis Alkaline Ceramidase Alopecia Animals Cell Differentiation Ceramides Energy Metabolism epidermis Female Hair Follicle Homeostasis Humans Keratinocytes Male Mice Mice Inbred C57BL Pituitary Gland Sebaceous Glands Skin Skin Abnormalities sphingolipids
Health amongst former rugby union players
Madeleine Davies, Andrew Judge, Antonella Delmestri, Simon Kemp, Keith Stokes, Nigel Arden, Julia Newton
Dec 01, 2017
In the general population, physical activity is associated with improved health outcomes. However, long-term sports participation may be associated with adverse outcomes, particularly at the elite level. The aims of this...
How Statistical Analysis Tools Can Be Used to Effectively Plan and Execute a Strategic Plan for an Organization
Brian Galli
Jan 01, 2021
However, pre-existing literature does not show how these variables, their concepts, and models help in strategic planning, which has resulted in a research gap. Thus, this study addresses the most current variables, their...
Published by: IGI Global Scientific Publishing
A Reflection Note on Applying Quantitative Decision-Making Approaches to Engineering Management
Engineering management is a project management activity full of information composed of specific engineering technology and different social factors. The basic knowledge of quantitative decision-making technology and management...
Published by: IGI Global Scientific Publishing
Cancer Markers Selection Using Network-Based Cox Regression
International initiatives such as the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) are collecting multiple datasets at different genome-scales with the aim of identifying novel cancer...
Measurement System Analysis and System Thinking in Six Sigma
Brian Galli
Jan 01, 2020
This article investigated measurement system analysis and system thinking in Six Sigma, as well as the factors that influence these actions. If the measurement system being used to accumulate data from the process delivers...
Published by: IGI Global Scientific Publishing
Optimization Methods in Continuous Improvement Models
Brian Galli
Jan 01, 2019
There are numerous processes used to implement quality, such as TQM, 6 Sigma, and Lean. For these quality processes to remain effective, a continuous improvement model is required and implemented from time to time. Some of these...
Published by: IGI Global Scientific Publishing
The Application of Systems Engineering to Project Management
Brian Galli
Jan 01, 2020
This study investigated the application of systems engineering to project management. There is an increasing complexity to modern projects, and lifecycle-focused project management displays the inability to manage the risks...
Published by: IGI Global Scientific Publishing
Economic Decision-Making and Risk Management
Brian Galli
Oct 01, 2021
Because of the recent financial crisis in the United States that shook the financial sector, the need for adopting effective Risk Management practices has increased. Essentially, the volatility of the sector calls for an...
Published by: IGI Global Scientific Publishing
Comparative Transcriptomics Reveals Clues for Differences in Pathogenicity between Hysterothylacium aduncum, Anisakissimplex sensu stricto and Anisakis pegreffii.
Serena Cavallero, Fabrizio Lombardo, Marco Salvemini, Antonella Pizzarelli, Cinzia Cantacessi, Stefano D'Amelio
Mar 18, 2020
Ascaridoid nematodes are widespread in marine fishes. Despite their major socioeconomic importance, mechanisms associated to the fish-borne zoonotic disease anisakiasis are still obscure. RNA-Seq and de-novo assembly were herein...
Application of Systems Engineering to Risk Management
Brian Galli
Apr 01, 2020
System engineering is an interdisciplinary field of engineering and engineering management that focuses on the design and management of the system. The system as a whole is the concern, which is followed by more technical...
Published by: IGI Global Scientific Publishing
Comparative Transcriptomics Reveals Clues for Differences in Pathogenicity between Hysterothylacium aduncum, Anisakis simplex sensu stricto and Anisakis pegreffii.
Serena Cavallero, Fabrizio Lombardo, Marco Salvemini, Antonella Pizzarelli, Cinzia Cantacessi, Stefano D'Amelio
Apr 21, 2020
Ascaridoid nematodes are widespread in marine fishes. Despite their major socioeconomic importance, mechanisms associated to the fish-borne zoonotic disease anisakiasis are still obscure. RNA-Seq and de-novo assembly were herein...
Published by: Genes
Comparative Transcriptomics Reveals Clues for Differences in Pathogenicity between Hysterothylacium aduncum, Anisakis simplex sensu stricto and Anisakis pegreffii
Serena Cavallero, Fabrizio Lombardo, Marco Salvemini, Antonella Pizzarelli, Cinzia Cantacessi, Stefano D’Amelio
Mar 25, 2020
Ascaridoid nematodes are widespread in marine fishes. Despite their major socioeconomic importance, mechanisms associated to the fish-borne zoonotic disease anisakiasis are still obscure. RNA-Seq and de-novo assembly were herein...
A School-Based Program to Promote Well-Being in Preadolescents
Elias Allara, Franca Beccaria, Roberta Molinar, Laura Marinaro, Antonella Ermacora, Alessandro Coppo, Fabrizio Faggiano, Diario della Salute Evaluation Support Team
Dec 19, 2018
Common and distinct transcriptional signatures of mammalian embryonic lethality.
John E Collins, Richard J White, Nicole Staudt, Ian M Sealy, Ian Packham, Neha Wali, Catherine Tudor, Cecilia Mazzeo, Angela Green, Emma Siragher, Edward Ryder, Jacqueline K White, Irene Papatheodoru, Amy Tang, Anja Füllgrabe, Konstantinos Billis, Stefan H Geyer, Wolfgang J Weninger, Antonella Galli, Myriam Hemberger, Derek L Stemple, Elizabeth Robertson, James C Smith, Timothy Mohun, David J Adams, Elisabeth M Busch-Nentwich
Aug 08, 2019
The Deciphering the Mechanisms of Developmental Disorders programme has analysed the morphological and molecular phenotypes of embryonic and perinatal lethal mouse mutant lines in order to investigate the causes of embryonic...
Resting-state functional connectivity MRI analysis in Human Immunodeficiency Virus and Hepatitis C Virus co-infected subjects. A pilot study.
Simone Corgiolu, Luigi Barberini, Jasjit S Suri, Antonella Mandas, Diego Costaggiu, Paola Piano, Fulvio Zaccagna, Pierleone Lucatelli, Antonella Balestrieri, Luca Saba
Jul 27, 2018
BACKGROUND AND PURPOSE: Hepatitis C virus (HCV) co-infection's role on cognitive impairment of human immunodeficiency virus (HIV) positive patients is still debated and functional neuroimaging evaluation on this matter is...
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