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Legacy of Cristina Grabiel to Continue at Winthrop
Winthrop University
Jan 01, 0001
Friends of Grabiel have established the Maria Cristina Grabiel y de la Guardia Fund, which will be used to provide awards for students pursuing careers in higher education or social justice and who have a vision for how they...
Published by: Winthrop University
The evolving view of the hematopoietic stem cell niche.
Hematopoietic stem cells (HSCs) reside in specialized microenvironments known as niches. The niche is essential to support HSC function and to maintain a correct balance between self-renewal and differentiation. Recent advances...
The effect of a change in co-payment on prescription drug demand in a National Health System
Cristina Hernández-Izquierdo, Beatriz González López-Valcárcel, Stephen Morris, Mariya Melnychuk, Ignacio Abásolo Alessón
Feb 24, 2020
OBJECTIVES: To test the heterogeneity of the effect of a change in pharmaceutical cost-sharing by therapeutic groups in a Spanish region. METHODS: Data: random sample (provided by the Canary Islands Health Service) of 40,471...
Unravelling compulsory happiness in exile
Natasha Tanna
Jul 19, 2018
A number of feminist critics of Latin American women writers in exile have suggested that women in exile may flourish as they are freed from the traditional gender restrictions imposed on them in their home countries. In this...
Cellular senescence in cancer
Hui‐Ling Ou, Reuben Hoffmann, Cristina González‐López, Gary J. Doherty, James E. Korkola, Daniel Muñoz‐Espín
Oct 01, 2021
Senescence refers to a cellular state featuring a stable cell‐cycle arrest triggered in response to stress. This response also involves other distinct morphological and intracellular changes including alterations in gene...
Published by: Molecular Oncology
Cellular senescence in cancer
Hui-Ling Ou, Reuben Hoffmann, Cristina González-López, Gary J Doherty, James E Korkola, Daniel Muñoz-Espín
Jan 18, 2021
Senescence refers to a cellular state featuring a stable cell-cycle arrest triggered in response to stress. This response also involves other distinct morphological and intracellular changes including alterations in gene...
Geoinformation Technologies in Land Use Monitoring of Fast-Growing Cities for Sustainable Urban Development
Cristina Henriques
Apr 09, 2021
To understand the territory of fast-growing cities, where there are multiple stakeholders involved, the observation of such dynamics seems indispensable to formulate and implement policies and actions based on a better...
Urban & Regional Development Geographic Information Systems Physical Sciences and Engineering Computer Science and Information Technology
Published by: IGI Global Scientific Publishing
Tail-regression estimator for heavy-tailed distributions of known tail indices and its application to continuum quantum Monte Carlo data.
Standard statistical analysis is unable to provide reliable confidence intervals on expectation values of probability distributions that do not satisfy the conditions of the central limit theorem. We present a regression-based...
Mitochondrial ROS Production Protects the Intestine from Inflammation through Functional M2 Macrophage Polarization.
Laura Formentini, Fulvio Santacatterina, Cristina Núñez de Arenas, Konstantinos Stamatakis, David López-Martínez, Angela Logan, Manuel Fresno, Ron Smits, Michael P Murphy, José M Cuezva
Aug 17, 2017
Mitochondria are signaling hubs in cellular physiology that play a role in inflammatory diseases. We found that partial inhibition of the mitochondrial ATP synthase in the intestine of transgenic mice triggers an...
ATP synthase Cytokines innate immunity Animals Cells Cultured Colitis Ulcerative Immunity Innate Intestines Macrophage Activation MACROPHAGES Mice Mice Inbred C57BL Mitochondria Mitochondrial Proton-Translocating ATPases NF-kappa B Phenotype Proto-Oncogene Proteins c-akt Reactive Oxygen Species STAT3 Transcription Factor Signal Transduction TOR Serine-Threonine Kinases
Changes in Day/Night Activity in the 6-OHDA-Induced Experimental Model of Parkinson's Disease
Catalina Requejo, Karmele López-de-Ipiña, José Ángel Ruiz-Ortega, Elsa Fernández, Pilar M Calvo, Teresa Morera-Herreras, Cristina Miguelez, Laura Cardona-Grifoll, Hodei Cepeda, Luisa Ugedo, José Vicente Lafuente
Oct 28, 2020
The search for experimental models mimicking an early stage of Parkinson's disease (PD) before motor manifestations is fundamental in order to explore early signs and get a better prognosis. Interestingly, our previous studies...
Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast.
Sophie R Atkinson, Samuel Marguerat, Danny A Bitton, Maria Rodríguez-López, Charalampos Rallis, Jean-François Lemay, Cristina Cotobal, Michal Malecki, Pawel Smialowski, Juan Mata, Philipp Korber, François Bachand, Jürg Bähler
Oct 10, 2018
Long noncoding RNAs (lncRNAs), which are longer than 200 nucleotides but often unstable, contribute a substantial and diverse portion to pervasive noncoding transcriptomes. Most lncRNAs are poorly annotated and understood...
NMD pathway RNA degradation Schizosaccharomyces pombe Antisense RNA cytoplasmic exonuclease pervasive transcription Cell Nucleus Cytoplasm Exonucleases Exosomes Fungal Proteins Gene Expression Profiling Gene Expression Regulation Fungal Meiosis Molecular Sequence Annotation Mutation RNA Interference RNA Stability RNA Fungal RNA Long Noncoding Schizosaccharomyces Sequence Analysis RNA
Moderate to vigorous physical activity and sedentary behavior changes in self-isolating adults during the COVID-19 pandemic in Brazil
Felipe Barreto Schuch, Rugero A Bulzing, Jacob Meyer, Guillermo F López-Sánchez, Igor Grabovac, Peter Willeit, Davy Vancampfort, Cristina M Caperchione, Kabir P Sadarangani, André O Werneck, Philip B Ward, Mark Tully, Lee Smith
Jul 28, 2021
BACKGROUND: The COVID-19 pandemic imposed major changes on daily-life routine worldwide. To the best of our knowledge, no study quantified the changes on moderate to vigorous physical activity (MVPA) and sedentary behaviors (SB)...
Digital Participatory Platforms for Urban Regeneration
Despite the increase in the globally connected population, there is still a high percentage of European citizens who do not have basic digital skills. In the era of smart cities, the Digital Divide affects the possibility for...
Published by: IGI Global Scientific Publishing
Omar Khayyam’s Epicureanism
This translation appears as the following chapter in:
Omar Khayyam’s Epicureanism: The Spanish Translations of Rubaiyats (1904-1930). Peripheral Transmodernities: South-to-South Dialogues Between the Luso-Hispanic World and “the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Omar Khayyam’s Epicureanism
This translation appears as the following chapter in:
Omar Khayyam’s Epicureanism: The Spanish Translations of Rubaiyats (1904-1930). Peripheral Transmodernities: South-to-South Dialogues Between the Luso-Hispanic World and “the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Omar Khayyam’s Epicureanism
This translation appears as the following chapter in:
Omar Khayyam’s Epicureanism: The Spanish Translations of Rubaiyats (1904-1930). Peripheral Transmodernities: South-to-South Dialogues Between the Luso-Hispanic World and “the...
Published by: Digital Commons @ Texas A&M University-San Antonio
Opening Pandora's Box
Global strategy research is rapidly increasing in quantity but is found in divergent literature and disciplines. Now is the time to offer a comprehensive review that identifies, synthesizes, and integrates previous research and...
Published by: IGI Global Scientific Publishing
Digital Health Literacy
Cristina Vaz de Almeida
Jan 01, 2021
Digital requires humanization. The pandemic has shown the importance of health organizations adapting rapidly to teleconsultation services, investing in e-health with quality criteria and monitoring outcomes. Through a...
Published by: IGI Global Scientific Publishing
The Impact of Customer Relationship Management Systems on Dynamic Capabilities at Firms
The banking industry has been forced to restructure its processes to get adapted to a more technological environment as a consequence of the changes experienced in the market. Academic literature has paid special attention to...
Published by: IGI Global Scientific Publishing
Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy.
Dorian Forte, María García-Fernández, Abel Sánchez-Aguilera, Vaia Stavropoulou, Claire Fielding, Daniel Martín-Pérez, Juan Antonio López, Ana SH Costa, Laura Tronci, Efterpi Nikitopoulou, Michael Barber, Paolo Gallipoli, Ludovica Marando, Carlos López Fernández de Castillejo, Alexandar Tzankov, Sabine Dietmann, Michele Cavo, Lucia Catani, Antonio Curti, Jesús Vázquez, Christian Frezza, Brian J Huntly, Juerg Schwaller, Simón Méndez-Ferrer
Sep 03, 2020
OXPHOS TCA cycle acute myeloid leukemia antioxidant bone marrow mesenchymal stem cells Chemotherapy Glutathione hematopoietic stem cell niche metabolic adaptation microenvironment Animals Antineoplastic Agents antioxidants Bone Marrow Cells Cultured Energy Metabolism Female Humans Leukemia Myeloid Acute Male Mesenchymal Stem Cells Mice Mice Inbred C57BL Middle Aged
Expectation of reward differentially modulates executive inhibition.
Paula M Herrera, Alberto Vélez Van Meerbeke, Mario Speranza, Claudia López Cabra, Mauricio Bonilla, Michaël Canu, Tristan A Bekinschtein
Mar 16, 2020
BACKGROUND: Inhibitory control, a key modulatory component of cognition guiding strategy and behaviour, can be affected by diverse contingencies. We explore here the effect of expectation of reward over behavioural adjustment in...
Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity.
Estela González-Gualda, Marta Pàez-Ribes, Beatriz Lozano-Torres, David Macias, Joseph R Wilson, Cristina González-López, Hui-Ling Ou, Sofía Mirón-Barroso, Zhenguang Zhang, Araceli Lérida-Viso, Juan F Blandez, Andrea Bernardos, Félix Sancenón, Miguel Rovira, Ljiljana Fruk, Carla P Martins, Manuel Serrano, Gary J Doherty, Ramón Martínez-Máñez, Daniel Muñoz-Espín
Mar 24, 2020
Pharmacologically active compounds with preferential cytotoxic activity for senescent cells, known as senolytics, can ameliorate or even revert pathological manifestations of senescence in numerous preclinical mouse disease...
Navitoclax (ABT-263) Cellular Senescence chemotherapy-induced senescence Lung cancer prodrug senolytics Thrombocytopenia Aniline Compounds Animals Antineoplastic Agents Apoptosis Blood Platelets Cell Survival Cellular Senescence Drug Screening Assays Antitumor Female Galactose Humans Mice Mice Inbred C57BL Mice SCID Molecular Structure Neoplasms Experimental prodrugs Sulfonamides Tumor Cells Cultured
Buying Through Social Platforms
Social platforms are currently encountering a set of burning issues: low ad conversion rates, cross-channel free-riding phenomena, lack of monetary incentives to retain premium content creators, etc. Direct purchase behaviors...
Published by: IGI Global Scientific Publishing
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