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Interview with Margaret Howell Heath
Margaret Howell Heath
Jan 01, 0001
In her October 12, 2006 interview with Nicole L. Wilson, Margaret Howell Heath explains why she joined the WAVES and shares her experiences being stationed in San Francisco. This interview was conducted for inclusion into the...
Published by: Winthrop University
Interview with Gwen P. Howell
Gwen P. Howell
Jan 01, 0001
Interview with Gwen P. Howell, member of the South Carolina Mothers Association.
Published by: Winthrop University
Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
A Saini, AR Norman, D Cunningham, I Chau, M Hill, D Tait, T Hickish, T Iveson, F Lofts, D Jodrell, PJ Ross, J Oates
Sep 02, 2020
We performed a multicentre randomised trial to compare the efficacy and toxicity of 12 weeks of 5-fluorouracil (5-FU) delivered by protracted intravenous infusion (PVI 5-FU) against the standard bolus regimen of 5-FU and folinic...
Enhancement of Adeno-Associated Virus-Mediated Gene Therapy Using Hydroxychloroquine in Murine and Human Tissues.
Laurel C Chandler, Alun R Barnard, Sarah L Caddy, Maria I Patrício, Michelle E McClements, Howell Fu, Cristina Rada, Robert E MacLaren, Kanmin Xue
Aug 12, 2020
The therapeutic effects of gene therapy using adeno-associated virus (AAV) vectors are dependent on the efficacy of viral transduction. Currently, we have reached the safe limits of AAV vector dose, beyond which damaging...
Secondary Metabolites of Osmanthus fragrans
Chen-Chen Fu, Fa-Ying Xu, Yu-Chen Qian, Hoi-Lun Koo, Yi-Fan Duan, Geng-Min Weng, Tai-Ping Fan, Mo-Xian Chen, Fu-Yuan Zhu
Aug 01, 2022
Osmanthus fragrans (scientific name: Osmanthus fragrans (Thunb.) Lour.) is a species of the Osmanthus genus in the family Oleaceae, and it has a long history of cultivation in China. O. fragrans is edible and is well known for...
On a new proposed mechanism of 5-fluorouracil-mediated cytotoxicity
Shobbir Hussain
May 01, 2020
The major molecular mode of action of the cytotoxic drug 5-fluorouracil (5-FU) is generally considered to result from thymidylate synthase inhibition. Recent findings relating to the function of the human uracil-5...
5-Fluorouracil 5-methyluridine DNA break repair NUD1 RNA methylation TRMT2A homologous recombination /dk/atira/pure/subjectarea/asjc/2700/2730 name=Oncology /dk/atira/pure/subjectarea/asjc/1300/1306 name=Cancer Research /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
Intensive Imaging-based Follow-up of Surgically Treated Localised Renal Cell Carcinoma Does Not Improve Post-recurrence Survival
Saeed Dabestani, Christian Beisland, Grant D Stewart, Karim Bensalah, Eirikur Gudmundsson, Thomas B Lam, William Gietzmann, Paimaun Zakikhani, Lorenzo Marconi, Sergio Fernandéz-Pello, Serenella Monagas, Samuel Paul Williams, Christian Torbrand, Thomas Powles, Erik Van Werkhoven, Richard Meijer, Alessandro Volpe, Michael Staehler, Börje Ljungberg, Axel Bex
Dec 03, 2018
The optimal follow-up (FU) strategy for patients treated for localised renal cell carcinoma (RCC) remains unclear. Using the RECUR database, we studied imaging intensity utilised in contemporary FU to evaluate its association...
Broadcast Faculty Member Recognized for Contributions to S.C. Broadcasters Association
Winthrop University
Jan 01, 0001
Howell was surprised with the news during an Oct. 21 broadcast at WRHI studios and will formally receive the award at the association conference on Jan. 13. Several Winthrop alumni who work in Charlotte, N.C., Rock Hill, S.C....
Published by: Winthrop University
Topical treatment of actinic keratoses in organ transplant recipients
Zeeshaan-Ul Hasan, Ikhlaaq Ahmed, Rubeta N Matin, Victoria Homer, John T Lear, Ferina Ismail, Tristan Whitmarsh, Adele C Green, Jason Thomson, Alan Milligan, Sarah Hogan, Vanessa Van-de-Velde, Liza Mitchell-Worsford, Jonathan Kentley, Claire Gaunt, Yolande Jefferson-Hulme, Sarah J Bowden, Piers Gaunt, Keith Wheatley, Charlotte M Proby, Catherine A Harwood
Jun 14, 2022
BACKGROUND: The risk of cutaneous squamous cell carcinoma (cSCC) is significantly increased in organ transplant recipients (OTRs). Clearance of actinic keratoses (AKs) is generally regarded as a surrogate biomarker for cSCC...
On a new proposed mechanism of 5-fluorouracil-mediated cytotoxicity
Shobbir Hussain
May 01, 2020
The major molecular mode of action of the cytotoxic drug 5-fluorouracil (5-FU) is generally considered to result from thymidylate synthase inhibition. Recent findings relating to the function of the human uracil-5...
5-Fluorouracil 5-methyluridine DNA break repair NUD1 RNA methylation TRMT2A homologous recombination /dk/atira/pure/subjectarea/asjc/2700/2730 name=Oncology /dk/atira/pure/subjectarea/asjc/1300/1306 name=Cancer Research /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being name=SDG 3 - Good Health and Well-being
A Corpus-Based Study on the Translation Style of Five English Versions of Fu Sheng Liu Ji, Vol I
Bing Zhang
Oct 31, 2022
Using a corpus approach, this article investigates the translation styles of the first chapter of Fu Sheng Liu Ji at three levels: the statistical parameters, the translation of culture-specific lexis, and readability...
Published by: IGI Global Scientific Publishing
The Ursinus Weekly, May 22, 1903
The character of Hamlet Monday Night Club Baseball Strawberry festival Robert E. Speer talks Society notes Alumni notes Recital Football schedule
Ursinus College Collegeville Pennsylvania newspaper Schaff literary society Zwinglian literary society baseball YMCA Football cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
The Ursinus Weekly, January 30, 1903
Hopefulness Three Girls One Evening American music student in Paris Casting Shadows, or Unconscious Influence YMCA Memorial Library Gymnasium work Society notes Alumni notes Locals Among the colleges Philadelphia letter
Ursinus College Collegeville Pennsylvania newspaper Schaff literary society Zwinglian literary society YMCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
SC3s
BACKGROUND: Today it is possible to profile the transcriptome of individual cells, and a key step in the analysis of these datasets is unsupervised clustering. For very large datasets, efficient algorithms are required to ensure...
SC3s
BACKGROUND: Today it is possible to profile the transcriptome of individual cells, and a key step in the analysis of these datasets is unsupervised clustering. For very large datasets, efficient algorithms are required to ensure...
The Evolution of ESMA and Direct Supervision
EJ Howell
Jun 15, 2017
The European Securities and Markets Authority (‘ESMA’) was established six years ago. It, and its sibling bodies for banking, and the insurance and occupational pensions sector, emerged from the ashes of the crises, and the...
Mechanistic and Physiological Studies of the Insulin-Dependent Regulation of FOXA2
Jessica Jean Howell
Jan 01, 0001
The Forkhead box A2 transcription factor (Foxa2/HNF-3β) has been shown to be a key regulator of genes involved in the maintenance of glucose and lipid homeostasis in the liver, and is constitutively inactivated in several...
Published by: Rockefeller University
EU Agencification and the Rise of ESMA
Elizabeth Howell
Apr 09, 2019
EU agencies have mushroomed in recent years and new agencies, such as those in the financial arena, can have far-reaching quasi-regulatory and supervisory powers. These developments raise fundamental questions as to their...
“Small, yet Beautiful”
We reconsider whether a grand multi-winner contest elicits more equilibrium effort than a collection of sub-contests. Fu and Lu (2009) employ a sequential winner-selection mechanism and find support for running a grand contest....
Bilateral Habenula deep brain stimulation for treatment-resistant depression
Chencheng Zhang, Yingying Zhang, Huichun Luo, Xinmeng Xu, Ti-Fei Yuan, Dianyou Li, Yi-Yun Cai, Hengfen Gong, Dai-Hui Peng, Yi-Ru Fang, Valerie Voon, Bomin Sun
Mar 07, 2022
Deep brain stimulation (DBS) of structures in the brain's reward system is a promising therapeutic option for patients with treatment-resistant depression (TRD). Recently, DBS of the habenula (HB) in the brain's anti-reward...
Short selling restrictions in the EU and the US
Elizabeth Howell
Jun 28, 2016
This is the author accepted manuscript. The final version is available from Taylor & Francis via https://doi.org/10.1080/14735970.2016.1198447
The Ursinus Weekly, October 23, 1903
John E. Hoyt, Linden Howell Rice, Edwin Milton Sando, Charles A. Townsend, Bertha E. Shipe
Jan 01, 0001
YMCA reception Alumni personals Football Literary Society notes Philadelphia letter A new musical organization Personals Literary Supplement: To the Tuscarora Mountain; Our Industrial Despot; A Snow Flake Wedding; The...
Ursinus College Collegeville Pennsylvania newspaper orchestra Zwinglian literary society Schaff literary society Football YMCA cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
Anti-tumour efficacy of capecitabine in a genetically engineered mouse model of pancreatic cancer.
Aurélie Courtin, Frances M Richards, Tashinga E Bapiro, Jo L Bramhall, Albrecht Neesse, Natalie Cook, Ben-Fillippo Krippendorff, David A Tuveson, Duncan I Jodrell
Feb 12, 2020
Capecitabine (CAP) is a 5-FU pro-drug approved for the treatment of several cancers and it is used in combination with gemcitabine (GEM) in the treatment of patients with pancreatic adenocarcinoma (PDAC). However, limited...
Animals Antineoplastic Combined Chemotherapy Protocols Capecitabine Carcinoma Pancreatic Ductal Cell Line Tumor Cytidine Deaminase Deoxycytidine Disease Models Animal Drug Screening Assays Antitumor Fluorouracil Mice Mice Transgenic Neoplasm Transplantation Pancreatic Neoplasms prodrugs Tissue Distribution Gemcitabine
Long-run marginal cost pricing based on network spare capacity
Fu-Rong Li
Jan 01, 0001
This paper proposes a novel approach for providing long-run marginal cost (LRMC) pricing in network charges. The proposed approach makes use of the unused capacity of an exiting network to reflect the cost of advancing or...
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