Individual plant cells have a genetic circuit, the circadian clock, that times key processes to the day-night cycle. These clocks are aligned to the day-night cycle by multiple environmental signals that vary across the plant....
Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect of cancer treatment, often associated with degeneration of sensory axons or their terminal regions. Presence of the slow Wallerian...
The sleeping sickness parasite Trypanosoma brucei has a complex life cycle, alternating between a mammalian host and the tsetse fly vector. A tightly controlled developmental programme ensures parasite transmission between hosts...
We introduce a universal sparse preconditioner that accelerates geometry optimisation and saddle point search tasks that are common in the atomic scale simulation of materials. Our preconditioner is based on the neighbourhood...
Campus Additions are Muddling Thru Dennis Gould Makes His Life in Art With "Inner Voice" Letters: GDI Supports Power's Points; Corson Operator Boxing Impersonal; Fashion Focus Offensive A "Civil" Voice Inspires Bookstore...
Larry Gould delivers lecture on Antarctic String ensemble plays at Founders' Day tea Flames wreck Olevian in spectacular blaze Grizzlies down F. & M. in thrilling contest Grapplers lose close meet to Temple, 16-14 Founders'...
Queen & football victory highlight Saturday's Homecoming festivities Students enjoy Winterthur visit Pre-medicals hear student talks Gould, Moser, Harris and Miller elected as freshman officers Recent Spike convocation...
The Arabidopsis circadian clock orchestrates gene regulation across the day/night cycle. Although a multiple feedback loop circuit has been shown to generate the 24-hr rhythm, it remains unclear how robust the clock is in...
The Human Silencing Hub (HUSH) complex is necessary for epigenetic repression of LINE-1 elements. We show that HUSH-depletion in human cell lines and primary fibroblasts leads to induction of interferon-stimulated genes (ISGs)...
OBJECTIVE: To assess family satisfaction with intensive care units (ICUs) in the UK using the Family Satisfaction in the Intensive Care Unit 24-item (FS-ICU-24) questionnaire, and to investigate how characteristics of patients...
Girls hold annual Lorelei dance Friday Junior elections postponed until Wednesday Larry Gould to lecture in Collegeville Tuesday Philadelphia alumni plan annual banquet Ursinus basketeers win two games, lose one Ursinus...
Bears annex first MAC championship Cold weather doesn't freeze "Mississippi mud" Senior show slated for May 16 Sir George Thomson, famed physicist, to speak at Commencement exercises Joyce Maloney wins title of Miss...
Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids, such as triacylglycerol (TG), as reservoirs of metabolic energy and membrane precursors. The Arf1/COPI protein machinery, known for its role in vesicle...