Autophagy is an evolutionarily conserved cellular process in which macromolecules undergo lysosomal degradation. It fulfills essential roles in quality controlling cellular constituents and in energy homeostasis. Basal autophagy...
Reduced autophagy has been implicated in aging, yet whether its loss can promote aging phenotypes and pathologies in mammals, and how reversible this process is, has never been fully explored. Using inducible short hairpin RNA...
Chromosomal instability is a hallmark of human cancer cells, but its role in carcinogenesis remains poorly resolved. Insights into this role have emerged from studies on the tumour suppressor BRCA2, whose inactivation in human...
BACKGROUND: Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status...
Abstract: A measurement of four branching-fraction ratios for three-body decays of B mesons involving two open-charm hadrons in the final state is presented. Run 1 and Run 2 pp collision data are used, recorded by the LHCb...
Cassidy's newest exhibition, "The Sound of Everything," is on display through July 16 in the Ross Gallery at Central Piedmont Community College. Who's the best artist on the Charlotte, North Carolina, arts scene? Winthrop...
Abstract: The first full angular analysis of the B0→D∗−Ds∗+ decay is performed using 6 fb−1 of pp collision data collected with the LHCb experiment at a centre-of-mass energy of 13 TeV. The Ds∗+→Ds+γ and D*− → D¯0π− vector meson...
Abstract: The decay-time-dependent CP asymmetry in B0→ D∗±D∓ decays is mea- sured using a data set corresponding to an integrated luminosity of 9 fb−1 recorded by the LHCb detector in proton-proton collisions at centre-of-mass...
A measurement of four branching-fraction ratios for three-body decays of $B$
mesons involving two open-charm hadrons in the final state is presented. Run 1
and Run 2 $pp$ collision data are used, recorded by the LHCb experiment...
BACKGROUND: Venous Thromboembolic disease (VTE) poses a diagnostic challenge for clinicians in acute care. Over reliance on reference standard investigations can lead to over treatment and potential harm. We sought to evaluate...
Abstract: The decay-time-dependent CP asymmetry in B0→ D∗±D∓ decays is mea- sured using a data set corresponding to an integrated luminosity of 9 fb−1 recorded by the LHCb detector in proton-proton collisions at centre-of-mass...
Abstract: The decay-time-dependent CP asymmetry in B0→ D∗±D∓ decays is mea- sured using a data set corresponding to an integrated luminosity of 9 fb−1 recorded by the LHCb detector in proton-proton collisions at centre-of-mass...
Abstract: Measurements of CP observables in B± → D(*)K± and B± → D(*)π± decays are presented, where D(∗) indicates a neutral D or D∗ meson that is an admixture of meson and anti-meson states. Decays of the D(∗) meson to the Dπ0...
Abstract: Measurements of CP observables in B± → D(*)K± and B± → D(*)π± decays are presented, where D(∗) indicates a neutral D or D∗ meson that is an admixture of meson and anti-meson states. Decays of the D(∗) meson to the Dπ0...
BACKGROUND: Venous Thromboembolic disease (VTE) poses a diagnostic challenge for clinicians in acute care. Over reliance on reference standard investigations can lead to over treatment and potential harm. We sought to evaluate...
Observational studies suggest that vitamin D deficiency is associated with higher risk of pain. However, evidence on the effect of vitamin D supplementation on pain is limited and contradictory. The aim of this study was to...
Vitamin D is an essential nutrient for bone health and may influence the risks of respiratory illness, adverse pregnancy outcomes, and chronic diseases of adulthood. Because many countries have a relatively low supply of foods...
A search for the $B^0_s \!\rightarrow D^{*\pm} D^\mp$ decay is performed
using proton-proton collision data at centre-of-mass energies of $7$, $8$ and
$13\,\text{TeV}$ collected by the LHCb experiment, corresponding to...
Measurements of $CP$ observables in $B^\pm \to D K^\pm$ and $B^\pm \to D
\pi^\pm$ decays are presented, where $D$ represents a superposition of $D^0$
and $\bar{D}^0$ states. The $D$ meson is reconstructed in the three-body...
Surfactant protein D (SP-D) is produced primarily in the lung and is involved in regulating pulmonary surfactants, lipid homeostasis and innate immunity. Circulating SP-D levels in blood are associated with chronic obstructive...
The decay-time-dependent $CP$ asymmetry in $B^0 \to D^{*\pm}D^{\mp}$ decays
is measured using a data set corresponding to an integrated luminosity of
$9$fb$^{-1}$ recorded by the LHCb detector in proton-proton collisions...