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Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.
Monica Ceccon, Maria Elena Boggio Merlo, Luca Mologni, Teresa Poggio, Lydia M Varesio, Matteo Menotti, Silvia Bombelli, Roberta Rigolio, Andrea D Manazza, Filomena Di Giacomo, Chiara Ambrogio, Giovanni Giudici, Cesare Casati, Cristina Mastini, Mara Compagno, Suzanne D Turner, Carlo Gambacorti-Passerini, Roberto Chiarle, Claudia Voena
Jan 08, 2016
Animals Apoptosis Blotting Western Cell Line Tumor Cell Survival Cells Cultured Crizotinib Dose-Response Relationship Drug Drug Synergism Extracellular Signal-Regulated MAP Kinases Histones Humans Hydrazines Lymphoma Large-Cell Anaplastic Mice Inbred NOD Mice Knockout Mice SCID Microscopy Confocal Nucleophosmin Oncogene Proteins Fusion Protein Kinase Inhibitors Protein-Tyrosine Kinases Pyrazoles Pyridines RNA Interference Signal Transduction Transplantation Heterologous Triazoles
Winthrop Dance Theatre 2015 Features Bodiography Creator Maria Caruso
Winthrop University
Jan 01, 0001
Maria Caruso created Bodiography to celebrate dancers of all shapes and sizes. When choreographer Maria Caruso created her company Bodiography, she set out to celebrate dancers of all shapes and sizes. She has since won acclaim...
Published by: Winthrop University
University Students' Foreign Language Learning Behaviours in the Online Environment
Given that the COVID-19 pandemic has strongly impacted students' learning experiences, the present research aims to reveal some of the challenges brought by the online foreign language classes in higher education and to show a...
Sustainable Development Education Curriculum Development and Instructional Design Social Sciences and Humanities Library and Information Science
Published by: IGI Global Scientific Publishing
The Interplay Between Career Adaptability and Foreign Language Skills in an Unstable Labor Market
Career adaptability is a soft skill that allows people to cope with professional tasks in an unpredictable labor market. Today's global labor market also requires language skills to facilitate employees' collaboration across...
Published by: IGI Global Scientific Publishing
Retrieval-Dependent Mechanisms Affecting Emotional Memory Persistence
Maladaptive emotional memories contribute to the persistence of many mental health disorders, and therefore the prospect of disrupting these memories to produce long-term reductions in relapse is of great clinical appeal....
Elucidating the Cognitive Mechanisms Underpinning Behavioural Activation.
Depression represents a pervasive and devastating psychological difficulty. It affects over 21% of the population at some point in their lives and can have an unimaginable impact on both individuals and society. Behavioural...
Integrating Multiple Research Methods to Unravel the Complexity of Human-Water Systems
Giuliano Di Baldassarre, Hannah Cloke, Sara Lindersson, Maurizio Mazzoleni, Elena Mondino, Johanna Mard, Vincent Odongo, Elena Raffetti, Elena Ridolfi, Maria Rusca, Elisa Savelli, Faranak Tootoonchi
Aug 11, 2021
Abstract: Predicting floods and droughts is essential to inform the development of policy in water management, climate change adaptation and disaster risk reduction. Yet, hydrological predictions are highly uncertain, while the...
Emergency Surgery in the Elderly
Background: the general population is aging across the world. Therefore, even surgical interventions in the elderly—in particular those involving emergency surgical admissions—are becoming more frequent. The elderly...
Monica Zese, Elena Finotti, Giovanni Cestaro, Fabio Cavallo, Daniela Prando, Tobia Gobbi, Riccardo Zese, Salomone Di Saverio, Ferdinando Agresta
Mar 15, 2021
E-Government and Semantics
The increasing digital transformation in all segments of society has been creating demand in information management and access. Consequently, local and federal governments must adapt and launch digital services that enable...
Information Resources Management Library and Information Science Information Resources Management Education Government and Law
Published by: IGI Global Scientific Publishing
Hepatic microRNA Expression by PGC-1α and PGC-1β in the Mouse.
Elena Piccinin, Maria Arconzo, Giusi Graziano, Michele Vacca, Claudia Peres, Elena Bellafante, Gaetano Villani, Antonio Moschetta
Feb 03, 2020
The fine-tuning of liver metabolism is essential to maintain the whole-body homeostasis and to prevent the onset of diseases. The peroxisome proliferator-activated receptor-γ coactivators (PGC-1s) are transcriptional key players...
Probing for Antibiotic Resistance Mechanisms in Ciprofloxacin Resistant Coliforms (CRCs) and Clarithromycin Resistant Enterococci (CREs)
Bacteria can acquire resistance to antimicrobials in a multitude of ways, causing antibiotic resistance to be a growing public health concern. This research coincides with Dr. Ellison's group with the production of...
antibiotic resistance Coliforms Enterococci Plasmids Biochemistry Biochemistry, Biophysics, and Structural Biology Life Sciences Molecular Biology
Published by: Ursinus College
Influence of Leadership Potential on the Effectiveness of Managerial Change
The current article puts forward the following hypothesis: leadership potential is the key to the effectiveness of changes taking place within business structures to ensure their functioning in the markets. In this context, the...
Published by: IGI Global Scientific Publishing
The Relevance of Immigrant Teachers' Experiences to Developing Professional Identity during a Teacher Requalification Program in Norway
As a result of increasing immigration to Norway and other European countries, many higher education institutions see a need to customize their educational programs or establish requalification programs for immigrants with...
Published by: IGI Global Scientific Publishing
Drosophila para bss Flies as a Screening Model for Traditional Medicine
Samuel S Dare, Emiliano Merlo, Jesus Rodriguez Curt, Peter E Ekanem, Nan Hu, Jimena Berni
Mar 01, 2021
Epilepsy is among the most common serious neurological disorders and affects around 50 million people worldwide, 80% of which live in developing countries. Despite the introduction of several new Anti-Epileptic Drugs (AEDs) in...
Moodle Learning System as an Effective Tool for Implementing the Innovation Policy of the University
The current study examines Moodle learning management system as an effective tool for implementing the innovation policy of the university. For this, the following methods are employed: (1) monitoring of the Best Global...
Published by: IGI Global Scientific Publishing
Sociology Faculty Member Compares Latino Immigrant Employment Experiences
Winthrop University
Jan 01, 0001
The session will be at 11 a.m. Sept. 3 in Dinkins Auditorium. The 2015-16 Provost's Spotlight on Scholarship Series kicks off Thursday, Sept. 3, with a lecture by Winthrop University Assistant Professor of Sociology Maria...
Published by: Winthrop University
Dr. Daniel F. Mahony Selected as President of Winthrop University
Winthrop University
Jan 01, 0001
Mahony will begin his duties on July 1, 2015. The President's House will be home to Mahony, his wife Laura and their two children, Gavin, 15, and Elena, 12. Dr. Daniel F. Mahony, dean of the College of Education, Health and...
Published by: Winthrop University
Making Discoveries that Transform Science
The Rockefeller University
Jan 01, 0001
Written and designed by the Office of Communications and Public Affairs for The Rockefeller University, this publication spotlights pathbreaking research of a few of the university's 75 major laboratories: Roderick MacKinnon...
Published by: The Rockefeller University
Winthrop to Host Variety of Events During Annual Come-See-Me Festival
Winthrop University
Jan 01, 0001
Several Winthrop University events are part of this year's festival, including the popular Teddy Bear Tea Party which will be hosted by First Lady Laura Mahony and daughter Elena. From dance showcases and plays to athletics and...
Published by: Winthrop University
A Novel Retrieval-Dependent Memory Process Revealed by the Arrest of ERK1/2 Activation in the Basolateral Amygdala.
Fully consolidated fear memories can be maintained or inhibited by retrieval-dependent mechanisms depending on the degree of re-exposure to fear cues. Short exposures promote memory maintenance through reconsolidation, and long...
Retrieval-Dependent Mechanisms Affecting Emotional Memory Persistence
Maladaptive emotional memories contribute to the persistence of many mental health disorders, and therefore the prospect of disrupting these memories to produce long-term reductions in relapse is of great clinical appeal....
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