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Transcription Factor Levels after Forward Programming of Human Pluripotent Stem Cells with GATA1, FLI1, and TAL1 Determine Megakaryocyte versus Erythroid Cell Fate Decision.
Amanda Dalby, Jose Ballester-Beltrán, Chiara Lincetto, Annett Mueller, Nicola Foad, Amanda Evans, James Baye, Ernest Turro, Thomas Moreau, Marloes R Tijssen, Cedric Ghevaert
Dec 21, 2018
erythroblast Forward programming lineage fate decision megakaryocyte Pluripotent Stem Cells Cell Differentiation Cell Lineage Cells Cultured Cytokines Erythroid Cells Erythropoietin GATA1 Transcription Factor Gene Silencing Humans Megakaryocytes Pluripotent Stem Cells Proto-Oncogene Protein c-fli-1 T-Cell Acute Lymphocytic Leukemia Protein 1 Thrombopoietin Transgenes
Development and testing of an intervention to increase staff knowledge and confidence in responding to health anxiety in the context of cognitive decline
Background: Memory complaint in the absence of organic pathology is a common phenomenon accounting for up to one third of patients presenting to memory clinics. Health anxiety has been specifically linked to dementia worry and...
ERT as Mobile Learning by Necessity
The term as below Emergency Remote Teaching (ERT) has been adopted worldwide. In practice, approaches to ERT have been contextual with diverse lecturer and student experiences owing to complex assemblages of sociomaterial...
Published by: IGI Global Scientific Publishing
Recent molecularly imprinted polymers applications in bioanalysis.
Foad Mashayekhi Suzaei, Seyed Mosayeb Daryanavard, Abbi Abdel-Rehim, Fatma Bassyouni, Mohamed Abdel-Rehim
Nov 09, 2022
Molecular imprinted polymers (MIPs) as extraordinary compounds with unique features have presented a wide range of applications and benefits to researchers. In particular when used as a sorbent in sample preparation methods for...
Considerations for Setting Up Play Therapy Training Clinics
When setting up a play therapy training clinic, there are many considerations to explore regarding designing a therapeutic space, selecting toys and other materials, exploring the rationale for the toy selection and examining...
Published by: IGI Global Scientific Publishing
Genetic background drives transcriptional variation in human induced pluripotent stem cells.
Foad Rouhani, Natsuhiko Kumasaka, Miguel Cardoso de Brito, Allan Bradley, Ludovic Vallier, Daniel Gaffney
Oct 14, 2020
Human iPS cells have been generated using a diverse range of tissues from a variety of donors using different reprogramming vectors. However, these cell lines are heterogeneous, which presents a limitation for their use in...
Development and testing of an intervention to increase staff knowledge and confidence in responding to health anxiety in the context of cognitive decline
Background: Memory complaint in the absence of organic pathology is a common phenomenon accounting for up to one third of patients presenting to memory clinics. Health anxiety has been specifically linked to dementia worry and...
Bouveret Syndrome
John Ong, Carla Swift, Benjamin G Stokell, Sharon Ong, Pierino Lucarelli, Arun Shankar, Foad J Rouhani, Yasseen Al-Naeeb
Sep 09, 2021
BACKGROUND AND GOALS: Bouveret syndrome is characterized by gastroduodenal obstruction caused by an impacted gallstone. Current literature recommends endoscopic therapy as the first line of intervention despite significantly...
Interface Engineering for Atomic Layer Deposited Alumina Gate Dielectric on SiGe Substrates.
L Zhang, Y Guo, VV Hassan, K Tang, MA Foad, JC Woicik, P Pianetta, J Robertson, PC McIntyre
Dec 02, 2016
Optimization of the interface between high-k dielectrics and SiGe substrates is a challenging topic due to the complexity arising from the coexistence of Si and Ge interfacial oxides. Defective high-k/SiGe interfaces limit...
Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells.
Foad J Rouhani, Serena Nik-Zainal, Arthur Wuster, Yilong Li, Nathalie Conte, Hiroko Koike-Yusa, Natsuhiko Kumasaka, Ludovic Vallier, Kosuke Yusa, Allan Bradley
Sep 20, 2018
The accuracy of replicating the genetic code is fundamental. DNA repair mechanisms protect the fidelity of the genome ensuring a low error rate between generations. This sustains the similarity of individuals whilst providing a...
Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells
Study of Immunoglobulin G Avidity to Herpes simplex 2 in Pregnant Egyptian Women
1Maysaa El Sayed Zaki, 1Douaa Raafat El- Deeb, 1Mona Fathy Foad Gorgy and 2Ahmed Mahmoud Badawy
Feb 02, 2015
Background: Herpes simplex virus is a DNA virus. It has two types herpes simplex 1 and herpes simplex 2. Affection of pregnant women by this virus carries adverse effect to the pregnancy outcomes.Aim: The aims of the current...
Published by: IJHS Medical Association
Growing importance of climate change beliefs for attitudes towards gas
Darrick Evensen, Lorraine Whitmarsh, Patrick Devine-Wright, Jen Dickie, Phil Bartie, Colin Foad, Mike Bradshaw, Stacia Ryder, Adam Mayer, Adam Varley
Mar 31, 2023
Tense global politics, spikes in gas prices and increasingly urgent warnings about climate change raise questions over the future use of natural gas. UK longitudinal survey data reveal that beliefs about climate change...
A Semantic Framework Supporting Multilayer Networks Analysis for Rare Diseases
Understanding the role played by genetic variations in diseases, exploring genomic variants and discovering disease-associated loci are among the most pressing challenges of genomic medicine. A huge and ever-increasing amount of...
Published by: IGI Global Scientific Publishing
Study of Immunoglobulin G Avidity to Herpes simplex 2 in Pregnant Egyptian Women
1Maysaa El Sayed Zaki, 1Douaa Raafat El- Deeb, 1Mona Fathy Foad Gorgy and 2Ahmed Mahmoud Badawy
Feb 02, 2015
Background: Herpes simplex virus is a DNA virus. It has two types herpes simplex 1 and herpes simplex 2. Affection of pregnant women by this virus carries adverse effect to the pregnancy outcomes.Aim: The aims of the current...
Published by: IJHS Medical Association
Participation in Software Development
Francis Harvey, Aura Moldovan, Eric Losang, Tim Leibert, Maria Turchenko, Nicola Simon, Rowenia Bender
Jan 01, 2022
Participatory planning holds important lessons for improving local government capabilities and responsiveness, but overall procedural regulations and statutory frameworks make its relevance for participatory IT development often...
Published by: IGI Global Scientific Publishing
Growing importance of climate change beliefs for attitudes towards gas
Darrick Evensen, Lorraine Whitmarsh, Patrick Devine-Wright, Jen Dickie, Phil Bartie, Colin Foad, Mike Bradshaw, Stacia Ryder, Adam Mayer, Adam Varley
Mar 31, 2023
Tense global politics, spikes in gas prices and increasingly urgent warnings about climate change raise questions over the future use of natural gas. UK longitudinal survey data reveal that beliefs about climate change...
Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia.
Irina Pleines, Joanne Woods, Stephane Chappaz, Verity Kew, Nicola Foad, José Ballester-Beltrán, Katja Aurbach, Chiara Lincetto, Rachael M Lane, Galina Schevzov, Warren S Alexander, Douglas J Hilton, William J Astle, Kate Downes, Paquita Nurden, Sarah K Westbury, Andrew D Mumford, Samya G Obaji, Peter W Collins, Fabien Delerue, Lars M Ittner, Nicole S Bryce, Mira Holliday, Christine A Lucas, Edna C Hardeman, Willem H Ouwehand, Peter W Gunning, Ernest Turro, Marloes R Tijssen, Benjamin T Kile
Feb 06, 2017
Integrating CBT and CFT within a case formulation approach to reduce depression and anxiety in an older adult with a complex mental and physical health history
Nicola Birdsey
Oct 12, 2020
Depression and anxiety are major contributors to growing healthcare costs in the UK, particularly with an increasingly ageing population. However, identification of mental health needs in older adults has been overshadowed by a...
Within school and beyond the gate
Nicola Ingram
Apr 01, 2011
Much educational research on working-class boys has focused on their failure and lack of aspiration. However, there has been little research on working-class boys’ experiences of success. The very idea of being educationally...
'I don’t wanna be mad and sad’
Nicola Birdsey
May 07, 2021
People with learning disabilities have historically been overlooked in research investigating the efficacy of therapeutic interventions, despite the increased prevalence of mental health difficulties among this population. As it...
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