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The Ontogeny and Function of Placental Macrophages.
The placenta is a fetal-derived organ whose function is crucial for both maternal and fetal health. The human placenta contains a population of fetal macrophages termed Hofbauer cells. These macrophages play diverse roles...
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No Evolution in the Half-mass Radius of Milky Way-type Galaxies over the Last 10 Gyr
Abstract The Milky Way (MW) galaxy is in focus, thanks to new observational data. Here we shed new light on the MW’s past by studying the structural evolution of MW progenitors...
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Novel 2-D Histogram-Based Soft Thresholding for Brain Tumor Detection and Image Compression
The objective of image compression is to extract meaningful clusters in a given image. Significant groups are possible with absolute threshold values. 1-D histogram-based multilevel thresholding is computationally complex and...
The Poor Old Heart of the Milky Way
Abstract Our Milky Way should host an ancient, metal-poor, and centrally concentrated stellar population, which reflects the star formation and enrichment in the few most massive...
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Association of CTLA-4 gene 49 G/A polymorphism in breast cancer patients with invasive ductal carcinoma
Background: Weak immunity surveillance has been the main reason for progression and rapid development of various cancers reported. Though the association between cytotoxic T-lymphocyte antigen 4 (CTLA-4) gene 49 G/A polymorphism...
Published by: IJHS Medical Association
Association of CTLA-4 gene 49 G/A polymorphism in breast cancer patients with invasive ductal carcinoma
Background: Weak immunity surveillance has been the main reason for progression and rapid development of various cancers reported. Though the association between cytotoxic T-lymphocyte antigen 4 (CTLA-4) gene 49 G/A polymorphism...
Published by: IJHS Medical Association
Impact of dengue fever on liver function tests and to relate liver function tests with severity of disease
Introduction: Dengue fever is an ancient disease. The earliest record found today is in a Chinese encyclopedia of disease symptoms and remedies, first published during Chin dynasty (265 to 420 AD). Severe Dengue was first...
Published by: IJHS Medical Association
Heat shock factor 1 is a substrate for p38 mitogen-activated Protein Kinases

Heat Shock Factor 1 (HSF1) monitors the structural integrity of the proteome. Phosphorylation at S326 is a hallmark for HSF1 activation, but the identity of the kinase(s) phosphorylating this site has remained elusive. We...

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Impact of dengue fever on liver function tests and to relate liver function tests with severity of disease
Introduction: Dengue fever is an ancient disease. The earliest record found today is in a Chinese encyclopedia of disease symptoms and remedies, first published during Chin dynasty (265 to 420 AD). Severe Dengue was first...
Published by: IJHS Medical Association
Heat shock factor 1 is a substrate for p38 mitogen-activated Protein Kinases

Heat Shock Factor 1 (HSF1) monitors the structural integrity of the proteome. Phosphorylation at S326 is a hallmark for HSF1 activation, but the identity of the kinase(s) phosphorylating this site has remained elusive. We...

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Two Remarkably Luminous Galaxy Candidates at z ≈ 10-12 Revealed by JWST
Abstract The first few 100 Myr at z > 10 mark the last major uncharted epoch in the history of the universe, where only a single galaxy (GN-z11 at...
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Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
The early detection of relapse following primary surgery for non-small-cell lung cancer and the characterization of emerging subclones, which seed metastatic sites, might offer new therapeutic approaches for limiting tumour...
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COVIDiSTRESS Global Survey dataset on psychological and behavioural consequences of the COVID-19 outbreak
Yuki Yamada, Dominik-Borna Ćepulić, Tao Coll-Martín, Stéphane Debove, Guillaume Gautreau, Hyemin Han, Jesper Rasmussen, Thao P. Tran, Giovanni A. Travaglino, Andreas Lieberoth, Angélique M. Blackburn, Loïs Boullu, Mila Bujić, Grace Byrne, Marjolein C. J. Caniëls, Ivan Flis, Marta Kowal, Nikolay R. Rachev, Vicenta Reynoso-Alcántara, Oulmann Zerhouni, Oli Ahmed, Rizwana Amin, Sibele Aquino, João Carlos Areias, John Jamir Benzon R. Aruta, Dastan Bamwesigye, Jozef Bavolar, Andrew R. Bender, Pratik Bhandari, Tuba Bircan, Huseyin Cakal, Tereza Capelos, Jiří Čeněk, Brendan Ch’ng, Fang-Yu Chen, Stavroula Chrona, Carlos C. Contreras-Ibáñez, Pablo Sebastián Correa, Irene Cristofori, Wilson Cyrus-Lai, Guillermo Delgado-Garcia, Eliane Deschrijver, Carlos Díaz, İlknur Dilekler, Vilius Dranseika, Dmitrii Dubrov, Kristina Eichel, Eda Ermagan-Caglar, Rebekah Gelpí, Rubén Flores González, Amanda Griffin, Moh Abdul Hakim, Krzysztof Hanusz, Yuen Wan Ho, Dayana Hristova, Barbora Hubena, Keiko Ihaya, Gozde Ikizer, Md. Nurul Islam, Alma Jeftic, Shruti Jha, Fernanda Pérez-Gay Juárez, Pavol Kacmar, Kalina Kalinova, Phillip S. Kavanagh, Mehmet Kosa, Karolina Koszałkowska, Raisa Kumaga, David Lacko, Yookyung Lee, Antonio G. Lentoor, Gabriel A. De Leon, Shiang-Yi Lin, Samuel Lins, Claudio Rafael Castro López, Agnieszka E. Lys, Samkelisiwe Mahlungulu, Tsvetelina Makaveeva, Salomé Mamede, Silvia Mari, Tiago A. Marot, Liz Martinez, Dar Meshi, Débora Jeanette Mola, Sara Morales-Izquierdo, Arian Musliu, Priyanka A. Naidu, Arooj Najmussaqib, Jean C. Natividade, Steve Nebel, Jana Nezkusilova, Irina Nikolova, Manuel Ninaus, Valdas Noreika, María Victoria Ortiz, Daphna Hausman Ozery, Daniel Pankowski, Tiziana Pennato, Martin Pírko, Lotte Pummerer, Cecilia Reyna, Eugenia Romano, Hafize Sahin, Aybegum Memisoglu Sanli, Gülden Sayılan, Alessia Scarpaci, Cristina Sechi, Maor Shani, Aya Shata, Pilleriin Sikka, Nidhi Sinha, Sabrina Stöckli, Anna Studzinska, Emilija Sungailaite, Zea Szebeni, Benjamin Tag, Mihaela Taranu, Franco Tisocco, Jarno Tuominen, Fidan Turk, Muhammad Kamal Uddin, Ena Uzelac, Sara Vestergren, Roosevelt Vilar, Austin Horng-En Wang, J. Noël West, Charles K. S. Wu, Teodora Yaneva, Yao-Yuan Yeh
Jan 04, 2021
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The trans-ancestral genomic architecture of glycemic traits.
Ji Chen, Cassandra N Spracklen, Gaëlle Marenne, Arushi Varshney, Laura J Corbin, Jian'an Luan, Sara M Willems, Ying Wu, Xiaoshuai Zhang, Momoko Horikoshi, Thibaud S Boutin, Reedik Mägi, Johannes Waage, Ruifang Li-Gao, Kei Hang Katie Chan, Jie Yao, Mila D Anasanti, Audrey Y Chu, Annique Claringbould, Jani Heikkinen, Jaeyoung Hong, Jouke-Jan Hottenga, Shaofeng Huo, Marika A Kaakinen, Tin Louie, Winfried März, Hortensia Moreno-Macias, Anne Ndungu, Sarah C Nelson, Ilja M Nolte, Kari E North, Chelsea K Raulerson, Debashree Ray, Rebecca Rohde, Denis Rybin, Claudia Schurmann, Xueling Sim, Lorraine Southam, Isobel D Stewart, Carol A Wang, Yujie Wang, Peitao Wu, Weihua Zhang, Tarunveer S Ahluwalia, Emil VR Appel, Lawrence F Bielak, Jennifer A Brody, Noël P Burtt, Claudia P Cabrera, Brian E Cade, Jin Fang Chai, Xiaoran Chai, Li-Ching Chang, Chien-Hsiun Chen, Brian H Chen, Kumaraswamy Naidu Chitrala, Yen-Feng Chiu, Hugoline G de Haan, Graciela E Delgado, Ayse Demirkan, Qing Duan, Jorgen Engmann, Segun A Fatumo, Javier Gayán, Franco Giulianini, Jung Ho Gong, Stefan Gustafsson, Yang Hai, Fernando P Hartwig, Jing He, Yoriko Heianza, Tao Huang, Alicia Huerta-Chagoya, Mi Yeong Hwang, Richard A Jensen, Takahisa Kawaguchi, Katherine A Kentistou, Young Jin Kim, Marcus E Kleber, Ishminder K Kooner, Shuiqing Lai, Leslie A Lange, Carl D Langefeld, Marie Lauzon, Man Li, Symen Ligthart, Jun Liu, Marie Loh, Jirong Long, Valeriya Lyssenko, Massimo Mangino, Carola Marzi, May E Montasser, Abhishek Nag, Masahiro Nakatochi, Damia Noce, Raymond Noordam, Giorgio Pistis, Michael Preuss, Laura Raffield, Laura J Rasmussen-Torvik, Stephen S Rich, Neil R Robertson, Rico Rueedi, Kathleen Ryan, Serena Sanna, Richa Saxena, Katharina E Schraut, Bengt Sennblad, Kazuya Setoh, Albert V Smith, Thomas Sparsø, Rona J Strawbridge, Fumihiko Takeuchi, Jingyi Tan, Stella Trompet, Erik van den Akker, Peter J van der Most, Niek Verweij, Mandy Vogel, Heming Wang, Chaolong Wang, Nan Wang, Helen R Warren, Wanqing Wen, Tom Wilsgaard, Andrew Wong, Andrew R Wood, Tian Xie, Mohammad Hadi Zafarmand, Jing-Hua Zhao, Wei Zhao, Najaf Amin, Zorayr Arzumanyan, Arne Astrup, Stephan JL Bakker, Damiano Baldassarre, Marian Beekman, Richard N Bergman, Alain Bertoni, Matthias Blüher, Lori L Bonnycastle, Stefan R Bornstein, Donald W Bowden, Qiuyin Cai, Archie Campbell, Harry Campbell, Yi Cheng Chang, Eco JC de Geus, Abbas Dehghan, Shufa Du, Gudny Eiriksdottir, Aliki Eleni Farmaki, Mattias Frånberg, Christian Fuchsberger, Yutang Gao, Anette P Gjesing, Anuj Goel, Sohee Han, Catharina A Hartman, Christian Herder, Andrew A Hicks, Chang-Hsun Hsieh, Willa A Hsueh, Sahoko Ichihara, Michiya Igase, M Arfan Ikram, W Craig Johnson, Marit E Jørgensen, Peter K Joshi, Rita R Kalyani, Fouad R Kandeel, Tomohiro Katsuya, Chiea Chuen Khor, Wieland Kiess, Ivana Kolcic, Teemu Kuulasmaa, Johanna Kuusisto, Kristi Läll, Kelvin Lam, Deborah A Lawlor, Nanette R Lee, Rozenn N Lemaitre, Honglan Li, Lifelines Cohort Study, Shih-Yi Lin, Jaana Lindström, Allan Linneberg, Jianjun Liu, Carlos Lorenzo, Tatsuaki Matsubara, Fumihiko Matsuda, Geltrude Mingrone, Simon Mooijaart, Sanghoon Moon, Toru Nabika, Girish N Nadkarni, Jerry L Nadler, Mari Nelis, Matt J Neville, Jill M Norris, Yasumasa Ohyagi, Annette Peters, Patricia A Peyser, Ozren Polasek, Qibin Qi, Dennis Raven, Dermot F Reilly, Alex Reiner, Fernando Rivideneira, Kathryn Roll, Igor Rudan, Charumathi Sabanayagam, Kevin Sandow, Naveed Sattar, Annette Schürmann, Jinxiu Shi, Heather M Stringham, Kent D Taylor, Tanya M Teslovich, Betina Thuesen, Paul RHJ Timmers, Elena Tremoli, Michael Y Tsai, Andre Uitterlinden, Rob M van Dam, Diana van Heemst, Astrid van Hylckama Vlieg, Jana V van Vliet-Ostaptchouk, Jagadish Vangipurapu, Henrik Vestergaard, Tao Wang, Ko Willems van Dijk, Tatijana Zemunik, Gonçalo R Abecasis, Linda S Adair, Carlos Alberto Aguilar-Salinas, Marta E Alarcón-Riquelme, Ping An, Larissa Aviles-Santa, Diane M Becker, Lawrence J Beilin, Sven Bergmann, Hans Bisgaard, Corri Black, Michael Boehnke, Eric Boerwinkle, Bernhard O Böhm, Klaus Bønnelykke, DI Boomsma, Erwin P Bottinger, Thomas A Buchanan, Mickaël Canouil, Mark J Caulfield, John C Chambers, Daniel I Chasman, Yii-Der Ida Chen, Ching-Yu Cheng, Francis S Collins, Adolfo Correa, Francesco Cucca, H Janaka de Silva, George Dedoussis, Sölve Elmståhl, Michele K Evans, Ele Ferrannini, Luigi Ferrucci, Jose C Florez, Paul W Franks, Timothy M Frayling, Philippe Froguel, Bruna Gigante, Mark O Goodarzi, Penny Gordon-Larsen, Harald Grallert, Niels Grarup, Sameline Grimsgaard, Leif Groop, Vilmundur Gudnason, Xiuqing Guo, Anders Hamsten, Torben Hansen, Caroline Hayward, Susan R Heckbert, Bernardo L Horta, Wei Huang, Erik Ingelsson, Pankow S James, Marjo-Ritta Jarvelin, Jost B Jonas, J Wouter Jukema, Pontiano Kaleebu, Robert Kaplan, Sharon LR Kardia, Norihiro Kato, Sirkka M Keinanen-Kiukaanniemi, Bong-Jo Kim, Mika Kivimaki, Heikki A Koistinen, Jaspal S Kooner, Antje Körner, Peter Kovacs, Diana Kuh, Meena Kumari, Zoltan Kutalik, Markku Laakso, Timo A Lakka, Lenore J Launer, Karin Leander, Huaixing Li, Xu Lin, Lars Lind, Cecilia Lindgren, Simin Liu, Ruth JF Loos, Patrik KE Magnusson, Anubha Mahajan, Andres Metspalu, Dennis O Mook-Kanamori, Trevor A Mori, Patricia B Munroe, Inger Njølstad, Jeffrey R O'Connell, Albertine J Oldehinkel, Ken K Ong, Sandosh Padmanabhan, Colin NA Palmer, Nicholette D Palmer, Oluf Pedersen, Craig E Pennell, David J Porteous, Peter P Pramstaller, Michael A Province, Bruce M Psaty, Lu Qi, Leslie J Raffel, Rainer Rauramaa, Susan Redline, Paul M Ridker, Frits R Rosendaal, Timo E Saaristo, Manjinder Sandhu, Jouko Saramies, Neil Schneiderman, Peter Schwarz, Laura J Scott, Elizabeth Selvin, Peter Sever, Xiao-Ou Shu, P Eline Slagboom, Kerrin S Small, Blair H Smith, Harold Snieder, Tamar Sofer, Thorkild IA Sørensen, Tim D Spector, Alice Stanton, Claire J Steves, Michael Stumvoll, Liang Sun, Yasuharu Tabara, E Shyong Tai, Nicholas J Timpson, Anke Tönjes, Jaakko Tuomilehto, Teresa Tusie, Matti Uusitupa, Pim van der Harst, Cornelia van Duijn, Veronique Vitart, Peter Vollenweider, Tanja GM Vrijkotte, Lynne E Wagenknecht, Mark Walker, Ya X Wang, Nick J Wareham, Richard M Watanabe, Hugh Watkins, Wen B Wei, Ananda R Wickremasinghe, Gonneke Willemsen, James F Wilson, Tien-Yin Wong, Jer-Yuarn Wu, Anny H Xiang, Lisa R Yanek, Loïc Yengo, Mitsuhiro Yokota, Eleftheria Zeggini, Wei Zheng, Alan B Zonderman, Jerome I Rotter, Anna L Gloyn, Mark I McCarthy, Josée Dupuis, James B Meigs, Robert A Scott, Inga Prokopenko, Aaron Leong, Ching-Ti Liu, Stephen CJ Parker, Karen L Mohlke, Claudia Langenberg, Eleanor Wheeler, Andrew P Morris, Inês Barroso, Meta-Analysis of Glucose and Insulin-related Traits Consortium (MAGIC)
Jun 07, 2021
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide...
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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Xiang Zhu, Shoa L Clarke, Konain Fatima Bhatti, Sailaja Vedantam, Thomas W Winkler, Adam E Locke, Eirini Marouli, Greg JM Zajac, Kuan-Han H Wu, Ioanna Ntalla, Qin Hui, Derek Klarin, Austin T Hilliard, Zeyuan Wang, Chao Xue, Gudmar Thorleifsson, Anna Helgadottir, Daniel F Gudbjartsson, Hilma Holm, Isleifur Olafsson, Mi Yeong Hwang, Sohee Han, Masato Akiyama, Saori Sakaue, Chikashi Terao, Masahiro Kanai, Wei Zhou, Ben M Brumpton, Humaira Rasheed, Aki S Havulinna, Yogasudha Veturi, Jennifer Allen Pacheco, Elisabeth A Rosenthal, Todd Lingren, Qiping Feng, Iftikhar J Kullo, Akira Narita, Jun Takayama, Hilary C Martin, Karen A Hunt, Bhavi Trivedi, Jeffrey Haessler, Franco Giulianini, Yuki Bradford, Jason E Miller, Archie Campbell, Kuang Lin, Iona Y Millwood, Asif Rasheed, George Hindy, Jessica D Faul, Wei Zhao, David R Weir, Constance Turman, Hongyan Huang, Mariaelisa Graff, Ananyo Choudhury, Dhriti Sengupta, Anubha Mahajan, Michael R Brown, Weihua Zhang, Ketian Yu, Ellen M Schmidt, Anita Pandit, Stefan Gustafsson, Xianyong Yin, Jian'an Luan, Jing-Hua Zhao, Fumihiko Matsuda, Hye-Mi Jang, Kyungheon Yoon, Carolina Medina-Gomez, Achilleas Pitsillides, Jouke Jan Hottenga, Andrew R Wood, Yingji Ji, Zishan Gao, Simon Haworth, Noha A Yousri, Ruth E Mitchell, Jin Fang Chai, Mette Aadahl, Anne A Bjerregaard, Jie Yao, Ani Manichaikul, Chii-Min Hwu, Yi-Jen Hung, Helen R Warren, Julia Ramirez, Jette Bork-Jensen, Line L Kårhus, Anuj Goel, Maria Sabater-Lleal, Raymond Noordam, Pala Mauro, Floris Matteo, Aaron F McDaid, Pedro Marques-Vidal, Matthias Wielscher, Stella Trompet, Naveed Sattar, Line T Møllehave, Matthias Munz, Lingyao Zeng, Jianfeng Huang, Bin Yang, Alaitz Poveda, Azra Kurbasic, Claudia Lamina, Lukas Forer, Markus Scholz, Tessel E Galesloot, Jonathan P Bradfield, Sanni E Ruotsalainen, EWarwick Daw, Joseph M Zmuda, Jonathan S Mitchell, Christian Fuchsberger, Henry Christensen, Jennifer A Brody, Miguel Vazquez-Moreno, Mary F Feitosa, Mary K Wojczynski, Zhe Wang, Michael H Preuss, Massimo Mangino, Paraskevi Christofidou, Niek Verweij, Jan W Benjamins, Jorgen Engmann, Noah L Tsao, Anurag Verma, Roderick C Slieker, Ken Sin Lo, Nuno R Zilhao, Phuong Le, Marcus E Kleber, Graciela E Delgado, Shaofeng Huo, Daisuke D Ikeda, Hiroyuki Iha, Jian Yang, Jun Liu, Ayşe Demirkan, Hampton L Leonard, Jonathan Marten, Mirjam Frank, Börge Schmidt, Laura J Smyth, Marisa Cañadas-Garre, Chaolong Wang, Masahiro Nakatochi, Andrew Wong, Nina Hutri-Kähönen, Xueling Sim, Rui Xia, Alicia Huerta-Chagoya, Juan Carlos Fernandez-Lopez, Valeriya Lyssenko, Suraj S Nongmaithem, Swati Bayyana, Heather M Stringham, Marguerite R Irvin, Christopher Oldmeadow, Han-Na Kim, Seungho Ryu, Paul RHJ Timmers, Liubov Arbeeva, Rajkumar Dorajoo, Leslie A Lange, Gauri Prasad, Laura Lorés-Motta, Marc Pauper, Jirong Long, Xiaohui Li, Elizabeth Theusch, Fumihiko Takeuchi, Cassandra N Spracklen, Anu Loukola, Sailalitha Bollepalli, Sophie C Warner, Ya Xing Wang, Wen B Wei, Teresa Nutile, Daniela Ruggiero, Yun Ju Sung, Shufeng Chen, Fangchao Liu, Jingyun Yang, Katherine A Kentistou, Bernhard Banas, Giuseppe Giovanni Nardone, Karina Meidtner, Lawrence F Bielak, Jennifer A Smith, Prashantha Hebbar, Aliki-Eleni Farmaki, Edith Hofer, Maoxuan Lin, Maria Pina Concas, Simona Vaccargiu, Peter J van der Most, Niina Pitkänen, Brian E Cade, Sander W van der Laan, Kumaraswamy Naidu Chitrala, Stefan Weiss, Amy R Bentley, Ayo P Doumatey, Adebowale A Adeyemo, Jong Young Lee, Eva Rb Petersen, Aneta A Nielsen, Hyeok Sun Choi, Maria Nethander, Sandra Freitag-Wolf, Lorraine Southam, Nigel W Rayner, Carol A Wang, Shih-Yi Lin, Jun-Sing Wang, Christian Couture, Leo-Pekka Lyytikäinen, Kjell Nikus, Gabriel Cuellar-Partida, Henrik Vestergaard, Bertha Hidalgo, Olga Giannakopoulou, Qiuyin Cai, Morgan O Obura, Jessica van Setten, Xiaoyin Li, Jingjing Liang, Hua Tang, Natalie Terzikhan, Jae Hun Shin, Rebecca D Jackson, Alexander P Reiner, Lisa Warsinger Martin, Zhengming Chen, Liming Li, Takahisa Kawaguchi, Joachim Thiery, Joshua C Bis, Lenore J Launer, Huaixing Li, Mike A Nalls, Olli T Raitakari, Sahoko Ichihara, Sarah H Wild, Christopher P Nelson, Harry Campbell, Susanne Jäger, Toru Nabika, Fahd Al-Mulla, Harri Niinikoski, Peter S Braund, Ivana Kolcic, Peter Kovacs, Tota Giardoglou, Tomohiro Katsuya, Dominique de Kleijn, Gert J de Borst, Eung Kweon Kim, Hieab HH Adams, M Arfan Ikram, Xiaofeng Zhu, Folkert W Asselbergs, Adriaan O Kraaijeveld, Joline WJ Beulens, Xiao-Ou Shu, Loukianos S Rallidis, Oluf Pedersen, Torben Hansen, Paul Mitchell, Alex W Hewitt, Mika Kähönen, Louis Pérusse, Claude Bouchard, Anke Tönjes, Yii-Der Ida Chen, Craig E Pennell, Trevor A Mori, Wolfgang Lieb, Andre Franke, Claes Ohlsson, Dan Mellström, Yoon Shin Cho, HyeJin Lee, Jian-Min Yuan, Woon-Puay Koh, Sang Youl Rhee, Jeong-Taek Woo, Iris M Heid, Klaus J Stark, Martina E Zimmermann, Henry Völzke, Georg Homuth, Michele K Evans, Alan B Zonderman, Ozren Polasek, Gerard Pasterkamp, Imo E Hoefer, Susan Redline, Katja Pahkala, Albertine J Oldehinkel, Harold Snieder, Ginevra Biino, Reinhold Schmidt, Helena Schmidt, Stefania Bandinelli, George Dedoussis, Thangavel Alphonse Thanaraj, Sharon LR Kardia, Patricia A Peyser, Norihiro Kato, Matthias B Schulze, Giorgia Girotto, Carsten A Böger, Bettina Jung, Peter K Joshi, David A Bennett, Philip L De Jager, Xiangfeng Lu, Vasiliki Mamakou, Morris Brown, Mark J Caulfield, Patricia B Munroe, Xiuqing Guo, Marina Ciullo, Jost B Jonas, Nilesh J Samani, Jaakko Kaprio, Päivi Pajukanta, Teresa Tusié-Luna, Carlos A Aguilar-Salinas, Linda S Adair, Sonny Augustin Bechayda, H Janaka de Silva, Ananda R Wickremasinghe, Ronald M Krauss, Jer-Yuarn Wu, Wei Zheng, Anneke Iden Hollander, Dwaipayan Bharadwaj, Adolfo Correa, James G Wilson, Lars Lind, Chew-Kiat Heng, Amanda E Nelson, Yvonne M Golightly, James F Wilson, Brenda Penninx, Hyung-Lae Kim, John Attia, Rodney J Scott, DC Rao, Donna K Arnett, Steven C Hunt, Mark Walker, Heikki A Koistinen, Giriraj R Chandak, Josep M Mercader, Maria C Costanzo, Dongkeun Jang, Noël P Burtt, Clicerio Gonzalez Villalpando, Lorena Orozco, Myriam Fornage, EShyong Tai, Rob M van Dam, Terho Lehtimäki, Nish Chaturvedi, Mitsuhiro Yokota, Jianjun Liu, Dermot F Reilly, Amy Jayne McKnight, Frank Kee, Karl-Heinz Jöckel, Mark I McCarthy, Colin NA Palmer, Veronique Vitart, Caroline Hayward, Eleanor Simonsick, Cornelia M van Duijn, Zi-Bing Jin, Jia Qu, Haretsugu Hishigaki, Xu Lin, Winfried März, Vilmundur Gudnason, Jean-Claude Tardif, Guillaume Lettre, Leen M 't Hart, Petra JM Elders, Scott M Damrauer, Meena Kumari, Mika Kivimaki, Pim van der Harst, Tim D Spector, Ruth JF Loos, Michael A Province, Esteban J Parra, Miguel Cruz, Bruce M Psaty, Ivan Brandslund, Peter P Pramstaller, Charles N Rotimi, Kaare Christensen, Samuli Ripatti, Elisabeth Widén, Hakon Hakonarson, Struan FA Grant, Lambertus ALM Kiemeney, Jacqueline de Graaf, Markus Loeffler, Florian Kronenberg, Dongfeng Gu, Jeanette Erdmann, Heribert Schunkert, Paul W Franks, Allan Linneberg, J Wouter Jukema, Amit V Khera, Minna Männikkö, Marjo-Riitta Jarvelin, Zoltan Kutalik, Cucca Francesco, Dennis O Mook-Kanamori, Ko Willems van Dijk, Hugh Watkins, David P Strachan, Niels Grarup, Peter Sever, Neil Poulter, Lee-Ming Chuang, Jerome I Rotter, Thomas M Dantoft, Fredrik Karpe, Matt J Neville, Nicholas J Timpson, Ching-Yu Cheng, Tien-Yin Wong, Chiea Chuen Khor, Hengtong Li, Charumathi Sabanayagam, Annette Peters, Christian Gieger, Andrew T Hattersley, Nancy L Pedersen, Patrik KE Magnusson, Dorret I Boomsma, Allegonda HM Willemsen, LAdrienne Cupples, Joyce BJ van Meurs, Mohsen Ghanbari, Penny Gordon-Larsen, Wei Huang, Young Jin Kim, Yasuharu Tabara, Nicholas J Wareham, Claudia Langenberg, Eleftheria Zeggini, Johanna Kuusisto, Markku Laakso, Erik Ingelsson, Goncalo Abecasis, John C Chambers, Jaspal S Kooner, Paul S de Vries, Alanna C Morrison, Scott Hazelhurst, Michèle Ramsay, Kari E North, Martha Daviglus, Peter Kraft, Nicholas G Martin, John B Whitfield, Shahid Abbas, Danish Saleheen, Robin G Walters, Michael V Holmes, Corri Black, Blair H Smith, Aris Baras, Anne E Justice, Julie E Buring, Paul M Ridker, Daniel I Chasman, Charles Kooperberg, Gen Tamiya, Masayuki Yamamoto, David A van Heel, Richard C Trembath, Wei-Qi Wei, Gail P Jarvik, Bahram Namjou, M Geoffrey Hayes, Marylyn D Ritchie, Pekka Jousilahti, Veikko Salomaa, Kristian Hveem, Bjørn Olav Åsvold, Michiaki Kubo, Yoichiro Kamatani, Yukinori Okada, Yoshinori Murakami, Bong-Jo Kim, Unnur Thorsteinsdottir, Kari Stefansson, Jifeng Zhang, YEugene Chen, Yuk-Lam Ho, Julie A Lynch, Daniel J Rader, Philip S Tsao, Kyong-Mi Chang, Kelly Cho, Christopher J O'Donnell, John M Gaziano, Peter WF Wilson, Timothy M Frayling, Joel N Hirschhorn, Sekar Kathiresan, Karen L Mohlke, Yan V Sun, Andrew P Morris, Michael Boehnke, Christopher D Brown, Pradeep Natarajan, Panos Deloukas, Cristen J Willer, Themistocles L Assimes, Gina M Peloso
Jan 27, 2023
BACKGROUND: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of...
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