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Results: 2259
Dynamics of multiple resistance mechanisms in plasma DNA during EGFR-targeted therapies in non-small cell lung cancer.
Dana Wai Yi Tsui, Muhammed Murtaza, Alvin Seng Cheong Wong, Oscar M Rueda, Christopher G Smith, Dineika Chandrananda, Ross A Soo, Hong Liang Lim, Boon Cher Goh, Carlos Caldas, Tim Forshew, Davina Gale, Wei Liu, James Morris, Francesco Marass, Tim Eisen, Tan Min Chin, Nitzan Rosenfeld
Aug 15, 2018
Circulating tumour DNA Liquid biopsy Lung cancer resistance mechanisms targeted therapy Antineoplastic Agents Carcinoma Non-Small-Cell Lung DNA Copy Number Variations DNA Mutational Analysis DNA Neoplasm Drug Resistance Neoplasm ErbB Receptors Gefitinib Humans Hydroxychloroquine Longitudinal Studies Lung Neoplasms Mutation Prognosis Survival Analysis Treatment Outcome Tumor Suppressor Protein p53
Full length talin stimulates integrin activation and axon regeneration.
Chin Lik Tan, Jessica CF Kwok, Janosch PD Heller, Rongrong Zhao, Richard Eva, James W Fawcett
May 20, 2015
Germline breast cancer susceptibility genes, tumor characteristics, and survival
Peh Joo Ho, Alexis J. Khng, Hui Wen Loh, Weang-Kee Ho, Cheng Har Yip, Nur Aishah Mohd-Taib, Veronique Kiak Mien Tan, Benita Kiat-Tee Tan, Su-Ming Tan, Ern Yu Tan, Swee Ho Lim, Suniza Jamaris, Yirong Sim, Fuh Yong Wong, Joanne Ngeow, Elaine Hsuen Lim, Mei Chee Tai, Eldarina Azfar Wijaya, Soo Chin Lee, Ching Wan Chan, Shaik Ahmad Buhari, Patrick M. Y. Chan, Juliana J. C. Chen, Jaime Chin Mui Seah, Wai Peng Lee, Chi Wei Mok, Geok Hoon Lim, Evan Woo, Sung-Won Kim, Jong Won Lee, Min Hyuk Lee, Sue K. Park, Alison M. Dunning, Douglas F. Easton, Marjanka K. Schmidt, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
Dec 15, 2021
Abstract: Background: Mutations in certain genes are known to increase breast cancer risk. We study the relevance of rare protein-truncating variants (PTVs) that may result in loss-of-function in breast cancer susceptibility...
Germline breast cancer susceptibility genes, tumor characteristics, and survival.
Peh Joo Ho, Alexis J Khng, Hui Wen Loh, Weang-Kee Ho, Cheng Har Yip, Nur Aishah Mohd-Taib, Veronique Kiak Mien Tan, Benita Kiat-Tee Tan, Su-Ming Tan, Ern Yu Tan, Swee Ho Lim, Suniza Jamaris, Yirong Sim, Fuh Yong Wong, Joanne Ngeow, Elaine Hsuen Lim, Mei Chee Tai, Eldarina Azfar Wijaya, Soo Chin Lee, Ching Wan Chan, Shaik Ahmad Buhari, Patrick MY Chan, Juliana JC Chen, Jaime Chin Mui Seah, Wai Peng Lee, Chi Wei Mok, Geok Hoon Lim, Evan Woo, Sung-Won Kim, Jong Won Lee, Min Hyuk Lee, Sue K Park, Alison M Dunning, Douglas F Easton, Marjanka K Schmidt, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
Jan 10, 2022
BACKGROUND: Mutations in certain genes are known to increase breast cancer risk. We study the relevance of rare protein-truncating variants (PTVs) that may result in loss-of-function in breast cancer susceptibility genes on...
Extreme Min – Cut Max – Flow Algorithm
In this article, the authors propose a maximum flow algorithm based on flow matrix. The algorithm only requires the effort to reduce the capacity of the underutilized arcs to that of the respective flow. The optimality of the...
Published by: IGI Global Scientific Publishing
Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development.
Andrew C Lin, Chin Lik Tan, Chien-Ling Lin, Laure Strochlic, Yi-Shuian Huang, Joel D Richter, Christine E Holt
Jun 16, 2011
Animals Axons Base Sequence Cytoplasm Fluorescent Antibody Technique Gene Expression Regulation In Situ Hybridization Molecular Sequence Data Plasmids Polyadenylation Protein Biosynthesis RNA Messenger Retinal Ganglion Cells Reverse Transcriptase Polymerase Chain Reaction Transcription Factors Xenopus Xenopus Proteins mRNA Cleavage and Polyadenylation Factors
Coarse-to-Fine
Facial structure editing of portrait images is challenging given the facial variety, the lack of ground-truth, the necessity of jointly adjusting color and shape, and the requirement of no visual artifacts. In this paper, we...
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma.
Li Ren Kong, Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Tuan Zea Tan, Nicholas L Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel SW Tan, N Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline SJ Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H Phillip Koeffler, Soo Chin Lee, Dennis Kappei, Huynh The Hung, Boon Cher Goh
Mar 25, 2021
c-MET receptors are activated in cancers through genomic events like tyrosine kinase domain mutations, juxtamembrane splicing mutation and amplified copy numbers, which can be inhibited by c-MET small molecule inhibitors. Here...
Animals Antineoplastic Agents Carcinoma Squamous Cell Cell Line Tumor Head and Neck Neoplasms Humans Lung Neoplasms Mice Mutation Phenotype Phosphorylation Polymorphism Genetic Prognosis Protein Binding Protein Interaction Domains and Motifs Protein Kinase Inhibitors Proto-Oncogene Proteins c-met Receptor ErbB-2 Signal Transduction Xenograft Model Antitumor Assays
On-line Biofilm Strength Detection in Cross-flow Membrane Filtration Systems
Stanislaus Raditya Suwarno, Wenhai Huang, Yong-Min Chew, Sio Hoong Henrich Tan, Augustinus Elmer Trisno, Yan Zhou
Jan 01, 0001
A fluid dynamic gauging (FDG) technique was used for on-line and in situ measurements of Pseudomonas aeruginosa PAO1 biofilm thickness and strength on flat sheet polyethersulphone membranes. The measurements are the first to...
Coarse-to-Fine
Facial structure editing of portrait images is challenging given the facial variety, the lack of ground-truth, the necessity of jointly adjusting color and shape, and the requirement of no visual artifacts. In this paper, we...
Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing.
Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models
Peh Joo Ho, Weang Kee Ho, Alexis J Khng, Yen Shing Yeoh, Benita Kiat-Tee Tan, Ern Yu Tan, Geok Hoon Lim, Su-Ming Tan, Veronique Kiak Mien Tan, Cheng-Har Yip, Nur-Aishah Mohd-Taib, Fuh Yong Wong, Elaine Hsuen Lim, Joanne Ngeow, Wen Yee Chay, Lester Chee Hao Leong, Wei Sean Yong, Chin Mui Seah, Siau Wei Tang, Celene Wei Qi Ng, Zhiyan Yan, Jung Ah Lee, Kartini Rahmat, Tania Islam, Tiara Hassan, Mei-Chee Tai, Chiea Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Xueling Sim, Alison M Dunning, Manjeet K Bolla, Antonis Antoniou, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
Apr 26, 2022
BACKGROUND: Family history, and genetic and non-genetic risk factors can stratify women according to their individual risk of developing breast cancer. The extent of overlap between these risk predictors is not clear. METHODS...
On-line Biofilm Strength Detection in Cross-flow Membrane Filtration Systems
Stanislaus Raditya Suwarno, Wenhai Huang, Yong-Min Chew, Sio Hoong Henrich Tan, Augustinus Elmer Trisno, Yan Zhou
Jan 01, 0001
A fluid dynamic gauging (FDG) technique was used for on-line and in situ measurements of Pseudomonas aeruginosa PAO1 biofilm thickness and strength on flat sheet polyethersulphone membranes. The measurements are the first to...
Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing.
Overlap of high-risk individuals predicted by family history, and genetic and non-genetic breast cancer risk prediction models
Peh Joo Ho, Weang Kee Ho, Alexis J Khng, Yen Shing Yeoh, Benita Kiat-Tee Tan, Ern Yu Tan, Geok Hoon Lim, Su-Ming Tan, Veronique Kiak Mien Tan, Cheng-Har Yip, Nur-Aishah Mohd-Taib, Fuh Yong Wong, Elaine Hsuen Lim, Joanne Ngeow, Wen Yee Chay, Lester Chee Hao Leong, Wei Sean Yong, Chin Mui Seah, Siau Wei Tang, Celene Wei Qi Ng, Zhiyan Yan, Jung Ah Lee, Kartini Rahmat, Tania Islam, Tiara Hassan, Mei-Chee Tai, Chiea Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Xueling Sim, Alison M Dunning, Manjeet K Bolla, Antonis C Antoniou, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
May 27, 2022
BACKGROUND: Family history, and genetic and non-genetic risk factors can stratify women according to their individual risk of developing breast cancer. The extent of overlap between these risk predictors is not clear. METHODS...
The screening and management of pituitary dysfunction following traumatic brain injury in adults
Chin Lik Tan, Seyed Alireza Alavi, Stephanie E Baldeweg, Antonio Belli, Alan Carson, Claire Feeney, Anthony P Goldstone, Richard Greenwood, David K Menon, Helen L Simpson, Andrew A Toogood, Mark Gurnell, Peter J Hutchinson
Jun 27, 2018
Pituitary dysfunction is a recognised, but potentially underdiagnosed complication of traumatic brain injury (TBI). Post-traumatic hypopituitarism (PTHP) can have major consequences for patients physically, psychologically...
Management pituitary dysfunction screening Traumatic brain injury Adrenal Insufficiency Adult Brain Injuries Traumatic Early Diagnosis Early Medical Intervention Female Follow-Up Studies Humans hypopituitarism Inappropriate ADH Syndrome Male Mass Screening Patient Admission Pituitary Function Tests Pituitary Gland Anterior United Kingdom
Validation of Submaximal Step Tests and the 6-Min Walk Test for Predicting Maximal Oxygen Consumption in Young and Healthy Participants.
Sung Hyun Hong, Hyuk In Yang, Dong-Il Kim, Tomas I Gonzales, Soren Brage, Justin Y Jeon
Jan 09, 2020
Background: This study aimed to test the validity of three different submaximal tests (i.e., 3-min step test with 20.3-cm step box height (3MST20), 3-min step test with 30-cm step box height (3MST30), and 6-min walk test (6MWT))...
Genetic analysis of wheat sensitivity to the ToxB fungal effector from Pyrenophora tritici-repentis, the causal agent of tan spot
Beatrice Corsi, Lawrence Percival-Alwyn, Rowena C. Downie, Luca Venturini, Elyce M. Iagallo, Camila Campos Mantello, Charlie McCormick-Barnes, Pao Theen See, Richard P. Oliver, Caroline S. Moffat, James Cockram
Jun 06, 2020
Abstract: Key message: Genetic mapping of sensitivity to the Pyrenophora tritici-repentis effector ToxB allowed development of a diagnostic genetic marker, and investigation of wheat pedigrees allowed transmission of sensitive...
Validation of Submaximal Step Tests and the 6-Min Walk Test for Predicting Maximal Oxygen Consumption in Young and Healthy Participants.
Sung Hyun Hong, Hyuk In Yang, Dong-Il Kim, Tomas I Gonzales, Soren Brage, Justin Y Jeon
Jan 03, 2020
Background: This study aimed to test the validity of three different submaximal tests (i.e., 3-min step test with 20.3-cm step box height (3MST20), 3-min step test with 30-cm step box height (3MST30), and 6-min walk test (6MWT))...
Using the ELM to Explore the Impact of Fake News on Panic Vaccination Intention
The study explores the effects of COVID-19 vaccine fake news on social media from the perspective of the elaboration likelihood model (ELM). The research model theorizes that factors of the central route and factors of the...
Published by: IGI Global Scientific Publishing
Genetic analysis of wheat sensitivity to the ToxB fungal effector from Pyrenophora tritici-repentis, the causal agent of tan spot.
Beatrice Corsi, Lawrence Percival-Alwyn, Rowena C Downie, Luca Venturini, Elyce M Iagallo, Camila Campos Mantello, Charlie McCormick-Barnes, Pao Theen See, Richard P Oliver, Caroline S Moffat, James Cockram
Jan 07, 2021
Genetic mapping of sensitivity to the Pyrenophora tritici-repentis effector ToxB allowed development of a diagnostic genetic marker, and investigation of wheat pedigrees allowed transmission of sensitive alleles to be tracked....
No metabolic effects of mustard allyl-isothiocyanate compared with placebo in men.
Mirjam Langeveld, Chong Yew Tan, Maarten R Soeters, Samuel Virtue, Laura PE Watson, Peter R Murgatroyd, Graeme K Ambler, Santiago Vidal-Puig, Krishna V Chatterjee, Antonio Vidal-Puig
Apr 11, 2018
Background: Induction of nonshivering thermogenesis can be used to influence energy balance to prevent or even treat obesity. The pungent component of mustard, allyl-isothiocyanate (AITC), activates the extreme cold receptor...
allyl-isothiocyanate energy expenditure mustard Thermogenesis thermogenic food Adolescent Adult Aged Animals Blood Glucose Body Temperature Cross-Over Studies Energy Intake Energy Metabolism Female Humans Hunger Isothiocyanates Male Mice Middle Aged Mustard Plant Norepinephrine Oxygen Consumption Thermogenesis Young Adult
The Grizzly, October 2, 2003
Lindsey Fund, Lauren A. Perotti, Quinn Dinsmore, Alexis Witt, Meg Gallagher, Defne Sarsilmaz, Amanda Bryman, Johanna Nash, Peter Bregman, Trevor Mohr, Monica Delaney, Eden Swick, Crystal McCarney, Marie DiFeliciantonio, Kyle Kauffman, Nicole Beck, Kevin Murphy, Matthew McDermott, Sara Maioli, Kimberly Salmon, Brandie Salenetri, Nicole Frates, Nicole Borocci, Kristen Grimmel, Eddie Murray, Brendan Bell, Aziz Shaikh, Laura Dougherty, Ray Baker
Jan 01, 0001
Sexual Assault Reported on Campus Water Worries Burst in Reimert Senior in the Market for Success Tough Crowd: Bush Speaks to the United Nations Opinions: Out of the Middle East, Part 4; Pharming: The Scariest New Drug Fad;...
Ursinus College Collegeville Pennsylvania newspaper cross country field hockey Football wrestling Volleyball Soccer Bomberger Memorial Hall Campus Activities Board Maples Hall Michael Casey Ernesto Mesinas sexual assault Reimert Hall cultural history Higher Education Liberal Studies Social History United States History
Published by: Ursinus College
A Critical Study on Translation of the Analects
Fan Min
Jan 01, 2021
“Ideology” shapes our discourse practices and is closely related to the translation activities. This paper attempts to explore how ideological factors influence the cultural transmission of Confucianism through a comparative...
Published by: IGI Global Scientific Publishing
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