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Results: 13374
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.
Parasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, Marie-Jo Halaby, Zahra Khan, Luis Palomero, Brandon Ho, Shili Duan, Jonathan St-Germain, Arash Algouneh, Francesca Mateo, Samah El Ghamrasni, Haithem Barbour, Daniel R Barnes, Jonathan Beesley, Otto Sanchez, Hal K Berman, Grant W Brown, El Bachir Affar, Georgia Chenevix-Trench, Antonis C Antoniou, Cheryl H Arrowsmith, Brian Raught, Miquel Angel Pujana, Karim Mekhail, Anne Hakem, Razqallah Hakem
Feb 15, 2021
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain...
Prediction of Piezoelectric Tile Performance in Flat and Mountainous Terrains Through Deep Neural Network
Jitendra Adhikari, Kamalpreet Singh, Anjani Kumar Sagar, Vikki Kumar Sharma, Rajeev Kumar, Satish Chandra Jain
Sep 13, 2023
Piezoelectric tiles harvest mechanical vibrations and convert them into electrical energy, making them an attractive energy-harvesting technology. However, their performance is heavily influenced by the terrain where they are...
energy harvesting experiment Finite element analysis Machine Learning piezoelectric materials /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2600/2612 name=Numerical Analysis /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/1000 name=General
R/BHC
BACKGROUND: Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in...
Prediction of Piezoelectric Tile Performance in Flat and Mountainous Terrains Through Deep Neural Network
Jitendra Adhikari, Kamalpreet Singh, Anjani Kumar Sagar, Vikki Kumar Sharma, Rajeev Kumar, Satish Chandra Jain
Sep 13, 2023
Piezoelectric tiles harvest mechanical vibrations and convert them into electrical energy, making them an attractive energy-harvesting technology. However, their performance is heavily influenced by the terrain where they are...
energy harvesting experiment Finite element analysis Machine Learning piezoelectric materials /dk/atira/pure/subjectarea/asjc/2600/2613 name=Statistics and Probability /dk/atira/pure/subjectarea/asjc/2600/2612 name=Numerical Analysis /dk/atira/pure/subjectarea/asjc/2600/2611 name=Modelling and Simulation /dk/atira/pure/subjectarea/asjc/1000 name=General
Mutual Clustered Redundancy and Composite Learning for Intrusion Detection Systems
In the area of cyber space security, intrusion detection is a challenging task which aims at the provision of security from various malicious attacks. Hence, this paper proposes a two-stage hybrid intrusion detection system...
Published by: IGI Global Scientific Publishing
PSK Method for Solving Mixed and Type-4 Intuitionistic Fuzzy Solid Transportation Problems
P. Kumar
Apr 01, 2019
In this article, the author categorises the solid transportation problem (STP) under uncertain environments. He formulates the mixed and fully intuitionistic fuzzy solid transportation problems (FIFSTPs) and utilizes the...
Published by: IGI Global Scientific Publishing
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Alphonse R. Dochez, 1925
The Rockefeller University
Jan 01, 0001
Alphonse R. Dochez. Etiology of Scarlet Fever
Lecture delivered January 17th, 1925
Posted with permission
Published by: J.B. Lippincott Company
Effect of ripple repetition rate on discrimination of ripple glide direction and the detection of brief tones in spectro-temporal ripple noise.
The effect of temporal repetition rate R on the discrimination and internal representation of stimuli with spectro-temporal ripples was examined. Experiment 1 measured the highest ripple density D at which upward- and...
Real-Time Mobile-Phone-Aided Melanoma Skin Lesion Detection Using Triangulation Technique
Melanoma is a harmful disease among all types of skin cancer. Genetic factors and the exposure of UV rays causes melanoma skin lesions. Early diagnosis is important to identify malignant melanomas to improve the patient...
Published by: IGI Global Scientific Publishing
Florence R. Sabin, 1915
The Rockefeller University
Jan 01, 0001
Prof. Florence R. Sabin. The Method of Growth of the Lymphatic System
Lecture delivered December 18th, 1915
Published by: J.B. Lippincott Company
Personality Antecedents of EWoM in Determining Online Customer Purchase Behavior
Electronic word of mouth (EWoM) is similar to the standard word of mouth- the only difference is, the use of Internet as a base in EWoM. By understanding the personality antecedents of EWoM, the consumer buyer beahviour could be...
Published by: IGI Global Scientific Publishing
Technological Solutions for Digital Identity
Digital transformation of enterprises is driving the need for a digital identity to recognize people for delivering services. The implementation of digital identity is complex, requiring several technological solutions and much...
Published by: IGI Global Scientific Publishing
Synthesis, Structures and Properties of Novel Platinum(II) Acetylide Complexes and Polymers with Tri(tolyl)phosphine as the Auxiliary Ligand
Abu Ali Ibn Sina, S. M. Ibrahim Al-rafia, Md. Faruak Ahmad, Ratan Kumar Paul, S. M. Saiful Islam, Muhammad Younus, Paul R. Raithby, Cheuk-lam Ho, Yih Hsing Lo, Li Liu, Hua Li, Wai-Yeung Wong
May 01, 2015
A new family of luminescent platinum(II) acetylide complexes and polymers were formed by the copper(I) catalyzed reaction of cis-[PtCl2(PR3)2] (R=C6H5–p-CH3) with appropriate acetylide ligands. The reaction of metal precursors...
The Expansion of Approximant /r/ in Dutch
Renée Van Bezooijen
Sep 30, 2014
In present-day Standard Dutch as spoken in the Netherlands, three main categories of pronunciation variants of Irl can be distinguished, namely alveolar /r/, uvular /r/, and approximant /r/. Approximant /r/, the focus of this...
Published by: Atlantic Provinces Linguistic Association
Comparative Evaluation of Post Operative Analgesic Effects of Intraperitoneal Levobupivacaine Plus Dexmedetidomine and Levobupivacaine Plus Clonidine in Patients Undergoing Laparoscopic Cholecystectomy.
Background and Aims: Local anaesthetics have been used widely through the intraperitoneal route, either alone or with various adjuvants, to effectively decrease the post operative pain after laparoscopic cholecystectomy...
Published by: IJHS Medical Association
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Segmentation of Pectoral Muscle in Mammograms Using Granular Computing
In this paper, pectoral muscle segmentation was performed to study the presence of malignancy in the pectoral muscle region in mammograms. A combined approach involving granular computing and layering was employed to locate the...
Published by: IGI Global Scientific Publishing
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes.
Taniya Bhardwaj, Kundlik Gadhave, Shivani K Kapuganti, Prateek Kumar, Zacharias Faidon Brotzakis, Kumar Udit Saumya, Namyashree Nayak, Ankur Kumar, Richa Joshi, Bodhidipra Mukherjee, Aparna Bhardwaj, Krishan Gopal Thakur, Neha Garg, Michele Vendruscolo, Rajanish Giri
Feb 20, 2023
Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis
Abstract Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA ...
Ramani Baddam, Narender Kumar, Lothar H Wieler, Aditya Kumar Lankapalli, Niyaz Ahmed, Sharon J Peacock, Torsten Semmler
May 30, 2018
Synthesis, Structures and Properties of Novel Platinum(II) Acetylide Complexes and Polymers with Tri(tolyl)phosphine as the Auxiliary Ligand
Abu Ali Ibn Sina, S. M. Ibrahim Al-rafia, Md. Faruak Ahmad, Ratan Kumar Paul, S. M. Saiful Islam, Muhammad Younus, Paul R. Raithby, Cheuk-lam Ho, Yih Hsing Lo, Li Liu, Hua Li, Wai-Yeung Wong
May 01, 2015
A new family of luminescent platinum(II) acetylide complexes and polymers were formed by the copper(I) catalyzed reaction of cis-[PtCl2(PR3)2] (R=C6H5–p-CH3) with appropriate acetylide ligands. The reaction of metal precursors...
Bayesian Spatial Modelling with R-INLA
The principles behind the interface to continuous domain spatial models in the R- INLA software package for R are described. The integrated nested Laplace approximation (INLA) approach proposed by Rue, Martino, and Chopin (2009)...
Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis.
Ramani Baddam, Narender Kumar, Lothar H Wieler, Aditya Kumar Lankapalli, Niyaz Ahmed, Sharon J Peacock, Torsten Semmler
Sep 26, 2018
Pyrazinamide (PZA) is an important first-line anti-tuberculosis drug, resistance to which occurs primarily due to mutations in pncA (Rv2043c) that encodes the pyrazinamidase enzyme responsible for conversion of pro-drug PZA into...
Anti-thrombotic efficacy of S007-867
Ankita Misra, Prem Prakash, Hobby Aggarwal, Priyanka Dhankani, Sachin Kumar, Chandra Prakash Pandey, Nicholas Pugh, Dominique Bihan, Manoj Kumar Barthwal, Richard W Farndale, Dinesh Kumar Dikshit, Madhu Dikshit
Mar 15, 2018
Pharmacological inhibition of platelet collagen interaction is a promising therapeutic strategy to treat intra-vascular thrombosis. S007-867 is a novel synthetic inhibitor of collagen-induced platelet aggregation. It has shown...
Blood Flow Velocity Collagen Hemostasis Platelet Activation Thrombosis Animals Aspirin Blood Coagulation Chlorides Clopidogrel Dose-Response Relationship Drug Ferric Compounds Fibrinolytic Agents Male Mice Piperidines Platelet Adhesiveness Platelet Aggregation Pyrrolidines Rats Rats Sprague-Dawley Thrombosis
Efficient One-Pot Solvothermal Synthesis and Characterization of Zirconia Nanoparticle-Decorated Reduced Graphene Oxide Nanocomposites
Nalinee Kanth Kadiyala, Badal Kumar Mandal, L Vinod Kumar Reddy, Crispin HW Barnes, Luis De Los Santos Valladares, Dwaipayan Sen
Feb 23, 2023
This study mainly deals with an effective one-pot solvothermal synthetic pathway for the preparation of uniformly dispersed zirconium oxide nanoparticles on the flattened rough surface of reduced graphene oxide (ZrO2/rGO NCs)...
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