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Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.
Davina Gale, Andrew RJ Lawson, Karen Howarth, Mikidache Madi, Bradley Durham, Sarah Smalley, John Calaway, Shannon Blais, Greg Jones, James Clark, Peter Dimitrov, Michelle Pugh, Samuel Woodhouse, Michael Epstein, Ana Fernandez-Gonzalez, Alexandra S Whale, Jim F Huggett, Carole A Foy, Gerwyn M Jones, Hadas Raveh-Amit, Karin Schmitt, Alison Devonshire, Emma Green, Tim Forshew, Vincent Plagnol, Nitzan Rosenfeld
Jul 16, 2018
INTRODUCTION: Detection and monitoring of circulating tumor DNA (ctDNA) is rapidly becoming a diagnostic, prognostic and predictive tool in cancer patient care. A growing number of gene targets have been identified as diagnostic...
Adult Alleles Biomarkers Tumor Cell-Free Nucleic Acids Circulating Tumor DNA DNA Mutational Analysis DNA Neoplasm Female High-Throughput Nucleotide Sequencing Humans Liquid biopsy Male Mutation Neoplasms Neoplastic Cells Circulating Polymerase Chain Reaction Reproducibility of Results Sensitivity and Specificity
Alterations in pain during adolescence and puberty
Hadas Nahman-Averbuch, Rui Li, Katelynn Boerner, Christopher Lewis, Sarah Garwood, Tonya Palermo, Abbie Jordan
Apr 30, 2023
During adolescence and puberty, alterations in pain, both experimental and clinical, are observed. In addition, adolescents undergo extensive biopsychosocial changes as they transition from childhood to adulthood. However, a...
Alterations in pain during adolescence and puberty
Hadas Nahman-Averbuch, Rui Li, Katelynn Boerner, Christopher Lewis, Sarah Garwood, Tonya Palermo, Abbie Jordan
Apr 30, 2023
During adolescence and puberty, alterations in pain, both experimental and clinical, are observed. In addition, adolescents undergo extensive biopsychosocial changes as they transition from childhood to adulthood. However, a...
Fuzzy Evaluation of Agricultural Water Conservancy Facilities in Reuse
It is increasingly important to reuse the wastewater conservancy facilities, which can further promote the development of agricultural economy. The basis of full investigation and research on the wastewater conservancy...
Published by: IGI Global Scientific Publishing
Impact of Mobile Banking Application Interactivity on Consumer Engagement
Amit Shankar
Dec 13, 2021
The study aims to examine the impact of mobile banking (m-banking) application interactivity on consumer engagement. The study also analyses the moderation effects of perceived security concerns, consumer innovativeness, and...
Published by: IGI Global Scientific Publishing
Current Dynamics and Future Growth of Online Travel Agencies
Although the literature on online travel agencies is growing, it is fragmented and incoherent. Hence, this review aims to synthesize the online travel agencies and suggest directions for future research on online travel...
Published by: IGI Global Scientific Publishing
Security of Medical Images Using a Key-Based Encryption Algorithm in the RDWT-RSVD Domain
Today, in the era of big data, an increasingly serious problem is the security of digital media in the healthcare domain. Encryption is a popular technique to resolve the security concern of medical data. In the paper, the...
Published by: IGI Global Scientific Publishing
Personality Influences Risk Perception in Online Shopping
Online shopping is a preferable alternative mode of shopping in the 21st century. The increase in the rate of online shoppers with increasing frequency of shopping pushes e-retailers to look into the buying pattern along with...
Published by: IGI Global Scientific Publishing
Localization in Wireless Sensor Networks for Accurate Event Detection
Event detection at its initial stage is considerably most demanding and more importantly challenging to reduce the causes and damages. The GPS-enabled sensor nodes are possibly a solution for the location estimation, but having...
Published by: IGI Global Scientific Publishing
Enhancing Behavioral Dependency for Effective Computing in Software
Software plays an important role in effective computing and communication of any services. It become crucial to identify some critical parts of the software that can lead to enhanced computing and increases efficiency of the...
Published by: IGI Global Scientific Publishing
Machine-Induced Vertical Responses of Single and Pile Groups
The main objective of this study is to understand the dynamic characteristic of pile foundations subjected to machine-based vertical vibrations. To accomplish this objective, forced vibration field tests are performed on hollow...
Published by: IGI Global Scientific Publishing
Island-Matrix Inhomogeneous Deformation Behavior, Formation of Deformation Band, and BUT Forming of DP Steel
Islands-Matrix-Dual-phase (I-M-DP) steel is received a great deal attention for better concern with the emissivity, fuel consumption and passengers safety. A number of deformation plasticity issues are yet to be fully...
Published by: IGI Global Scientific Publishing
Information and Communication Technology Adoption Strategies of Emerging Multinationals From India
The growth and rising prominence of multinationals from emerging markets (eMNCs) mark a significant phase in the evolution of the world economy in the last decade. This study investigates the effect of eMNCs' institutional...
Published by: IGI Global Scientific Publishing
Evolution of Artificial Intelligence in Bone Fracture Detection
The objective of the paper is to present the techniques of Artificial Intelligence based on deep learning that can be applied to detect fractures in bones on X-rays. The paper comprises of discussions of various entities....
Published by: IGI Global Scientific Publishing
Radically filtered quasi-hereditary algebras and rigidity of tilting modules
Abstract LetA be a quasi-hereditary algebra. We prove that in many cases, a tilting module is rigid (i.e. has identical radical and socle series) if it does not have...
AMIT HAZI
Apr 07, 2017
Research on Linear Programming Algorithm for Mathematical Model of Agricultural Machinery Allocation
The objective of this paper is to study the linear programming algorithm of the mathematical model of agricultural machinery allocation when there are many farmland projects and cross operations. In this paper, combined with the...
Published by: IGI Global Scientific Publishing
Reliability-Based Fragility Analysis of RC Frame Buildings Considering Soil-Structure Interaction
In the present study, the effect of soil structure interaction (SSI) of low, mid, and high rise (G+1, G+4, and G+9 storey) buildings has been evaluated by nonlinear dynamic analysis using three-dimensional finite element method....
Published by: IGI Global Scientific Publishing
IoT-Based Framework for Smart Agriculture
Agriculture plays an important role in the making and development of a country. In India, agriculture is the primary source of living for more than about 60% of its population. The agriculture-related issues always hinder the...
Published by: IGI Global Scientific Publishing
Applying Service-Dominant Logic and Conversation Management Principles to Social Robotics for Autism Spectrum Disorder
Anthropomorphism in social robots amplifies the big five human personality traits (extraversion, conscientiousness, neuroticism, openness to experience, and agreeableness), consequently aiding with the social motivation needs of...
Published by: IGI Global Scientific Publishing
Internet of Things-Based Agricultural Mechanization Using Neural Network Extreme Learning on Rough Set
Recently, the basic functioning of monitoring in internet of things (IoT) is to apply the monitored data to the database for the regular analysis through mobile or computer platform. The purpose of this article is to highlight...
Environmental Technologies Environmental Agricultural and Physical Sciences Environmental Science and Technologies
Published by: IGI Global Scientific Publishing
On the Structure of Linear Dislocation Field Theory
Uniqueness of solutions in the linear theory of non-singular dislocations, studied as a special case of plasticity theory, is examined. The status of the classical, singular Volterra dislocation problem as a limit of plasticity...
A Text Analytics Framework for Performance Assessment and Weakness Detection From Online Reviews
Present research proposes a framework that integrates aspect-level sentiment analysis with multi-criteria decision making (TOPSIS) and control charts to uncover hidden quality patterns. While sentiment analysis quantifies...
Published by: IGI Global Scientific Publishing
A Machine Learning-Based Wrapper Method for Feature Selection
This paper presents a two-stage feature selection scheme using machine learning techniques. In the first stage a wrapper method is adopted to select various combinations of subsets of features from the original dataset. The...
Published by: IGI Global Scientific Publishing
Intrusion Detection System
The use of encrypted data, the diversity of new protocols, and the surge in the number of malicious activities worldwide have posed new challenges for intrusion detection systems (IDS). In this scenario, existing signature-based...
Published by: IGI Global Scientific Publishing
Time Effective Cloud Resource Scheduling Method for Data-Intensive Smart Systems
The cloud computing platforms are being deployed nowadays for resource scheduling of real time data intensive applications. Cloud computing still deals with the challenge of time oriented effective scheduling for resource...
Published by: IGI Global Scientific Publishing
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