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Results: 237
Comparing oncology clinical programs by use of innovative designs and expected net present value optimization
Tom Parke, Olga Marchenko, Vladimir Anisimov, Anastasia Ivanova, Christopher Jennison, Inna Perevozskaya, Guochen Song
Jan 01, 0001
Designing an oncology clinical program is more challenging than designing a single study. The standard approaches have been proven to be not very successful during the last decade; the failure rate of Phase 2 and Phase 3...
Comparing oncology clinical programs by use of innovative designs and expected net present value optimization
Tom Parke, Olga Marchenko, Vladimir Anisimov, Anastasia Ivanova, Christopher Jennison, Inna Perevozskaya, Guochen Song
Jan 01, 0001
Designing an oncology clinical program is more challenging than designing a single study. The standard approaches have been proven to be not very successful during the last decade; the failure rate of Phase 2 and Phase 3...
Philanthropic Music Showcase to Welcome President Mahony, Commemorate Vladimir Horowitz Anniversary
Winthrop University
Jan 01, 0001
The showcase will be Oct. 4 at 4 p.m. in Frances May Barnes Recital Hall. The Steinway Piano Gallery of Charlotte will help Winthrop University's Department of Music welcome President Dan Mahony, raise money for charity and...
Published by: Winthrop University
Launching of ships from horizontal berth by tipping tables – CFD simulation of wave generation
The paper considers the side launching of ships from a horizontal berth by tipping tables. The launching process is split into the six phases and a system of nonlinear di erential equations of motion is established. The system...
The Lantern Vol. 7, No. 3, June 1939
Valerie H. Green, Esther Hydren, Robert C. Yoh, Dorothy Kinsey Shisler, Kenneth Snyder, Evelyn Huber, Robert B. N. Peck, Marion Byron, Gladys Heibel, Ellen McMurtrie
Jan 01, 0001
Commencement Sonnet Largo Appassionato More Sonnets to Earth Vladimir Abe Lincoln in Illinois Dark Lives Enter Mr. Smithingham II A Character is Sketched Sonnet Out of the Dawn Wistaria Poem Without a...
Ursinus College Collegeville Pennsylvania Lantern Literary Magazine poetry fiction Creative Nonfiction Robert Sherwood Abraham Lincoln Abe Lincoln in Illinois play Arts and Humanities Creative Writing fiction illustration Nonfiction poetry
Published by: Ursinus College
Questimonial: Lolita
Diane Skorina
Jan 01, 0001
Lolita, by Vladimir Nabokov, has been this author's favorite book for the past twenty-five years. This Questimonial explores the Ursinus Quest core questions of "What should matter to me?" and "How should we live together?"...
Vladimir Nabokov Lolita Ursinus College Quest curriculum open questions Curriculum and Social Inquiry Higher Education
Published by: Ursinus College
Fast Track to Full Online Education in the Medical Field
The research explores the key issues specific to the online learning format. The scholars surveyed 1540 students and teachers to collect the data. The purpose was to identify and find solutions to the distance learning problems...
Published by: IGI Global Scientific Publishing
Structure-Hepatoprotective Activity Relationship Study of Iridoids
Iridoids, the largest class of monoterpenoids, are widespread group of substances present in various plant organisms. This study is devoted to investigation of the hepatoprotective activity of a series of iridoid compounds with...
Published by: IGI Global Scientific Publishing
One Man's Reaction to NATO Expansion
Jamie M Putnam
Jan 01, 0001
Using the policy of NATO expansion and the events of the Ukraine crisis, this paper examines President Vladimir Putin's impact on Russian foreign policy and analyzes the extent to which his personality and personal interests...
NATO expansion Ukraine crisis Vladimir Putin individual in leadership Russian Federation foreign affairs Cold War KGB Soviet Union Boris Yeltsin North Atlantic Treaty Organization Diplomatic History International Relations Leadership Studies political history Political Science Social and Behavioral Sciences Soviet and Post-Soviet Studies
Published by: Ursinus College
Xavier Tilliette on Revelation as the Measure of Reason
Tyler Tritten
Apr 05, 2022
Xavier Tilliette, born in Sommes, France in 1921, passed away on 10 December 2018 at the age of 97. Although he first gained notoriety for his many studies of Schelling, he has also published numerous books and articles on...
Published by: Memorial University Libraries
Xavier Tilliette on Revelation as the Measure of Reason
Tyler Tritten
Apr 05, 2022
Xavier Tilliette, born in Sommes, France in 1921, passed away on 10 December 2018 at the age of 97. Although he first gained notoriety for his many studies of Schelling, he has also published numerous books and articles on...
Published by: Memorial University Libraries
Heat Recovery of Low-Grade Energy Sources in the System of Preparation of Biogas Plant Substrates
Preliminary preparation of waste for anaerobic digestion at thermophilic temperature conditions is the most energy-intensive stage of the process of anaerobic bioconversion of production and consumption waste organic matter...
Published by: IGI Global Scientific Publishing
Obtaining the Dynamic Coefficients of Structuredness for Assessing a Domain
Today, effective management of information requires an in-depth study of its internal organization. The structural organization of information affects the efficiency of choosing a method for solving the problem and the...
Published by: IGI Global Scientific Publishing
GDF15
GDF15 has recently gained scientific and translational prominence with the discovery that its receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain. Activation of this receptor results in...
The 2021 room-temperature superconductivity roadmap.
Boeri Lilia, Richard Hennig, Peter Hirschfeld, Gianni Profeta, Antonio Sanna, Eva Zurek, Warren E Pickett, Maximilian Amsler, Ranga Dias, Mikhail I Eremets, Christoph Heil, Russell J Hemley, Hanyu Liu, Yanming Ma, Carlo Pierleoni, Aleksey N Kolmogorov, Nikita Rybin, Dmitry Novoselov, Vladimir Anisimov, Artem R Oganov, Chris J Pickard, Tiange Bi, Ryotaro Arita, Ion Errea, Camilla Pellegrini, Ryan Requist, EKU Gross, Elena Roxana Margine, Stephen R Xie, Yundi Quan, Ajinkya Hire, Laura Fanfarillo, GR Stewart, JJ Hamlin, Valentin Stanev, Renato S Gonnelli, Erik Piatti, Davide Romanin, Dario Daghero, Roser Valenti
Mar 08, 2022
Designing materials with advanced functionalities is the main focus of contemporary solid-state physics and chemistry. Research efforts worldwide are funneled into a few high-end goals, one of the oldest, and most fascinating of...
Socio-Demographic Impacts on the Personal Savings Portfolio Choice
Insufficiently developed financial system, poor standard of living and inappropriate education of citizens on the saving products, lead to low level of investment in the financial market of developing countries. In this paper...
Published by: IGI Global Scientific Publishing
Renormalon approach to higher twist distribution amplitudes and the convergence of the conformal expansion.
Power corrections to exclusive processes are usually calculated using models for twist–four
distribution amplitudes (DA) which are based on the leading–order terms in the conformal
expansion. In this work we develop a different...
Published by: HEP, Cavendish Laboratory, University of Cambridge
Transcriptomics-Based Phenotypic Screening Supports Drug Discovery in Human Glioblastoma Cells
Vladimir Shapovalov, Liliya Kopanitsa, Lavinia-Lorena Pruteanu, Graham Ladds, David S. Bailey
Jul 28, 2021
We have used three established human glioblastoma (GBM) cell lines—U87MG, A172, and T98G—as cellular systems to examine the plasticity of the drug-induced GBM cell phenotype, focusing on two clinical drugs, the phosphodiesterase...
Nonexistence of subcritical solitary waves
We prove the nonexistence of two-dimensional solitary gravity water waves with subcritical wave speeds and an arbitrary distribution of vorticity. This is a longstanding open problem, and even in the irrotational case there are...
Influence of precursors on the induction period and transition regime of dimethyl ether conversion to hydrocarbons over ZSM-5 catalysts
ZSM-5 catalysts were subjected to step response cycles of dimethyl ether (DME) at 300 °C in a temporal analysis of product (TAP) reactor. Propylene is the major olefin and displays an S-shaped profile. A 44 min induction...
Nonexistence of subcritical solitary waves
We prove the nonexistence of two-dimensional solitary gravity water waves with subcritical wave speeds and an arbitrary distribution of vorticity. This is a longstanding open problem, and even in the irrotational case there are...
Subriemannian metrics and the metrizability of parabolic geometries
We present the linearized metrizability problem in the context of parabolic geometries and subriemannian geometry, generalizing the metrizability problem in projective geometry studied by R. Liouville in 1889. We give a general...
Russia’s Ministry of Ambivalence
J. Paul Goode
Feb 05, 2019
This article argues that the sources of official and societal ambivalence towards civic nationhood in today’s Russia are found in the institutional instability and personalist dynamics of hybrid regime politics in the 1990s....
Russia’s Ministry of Ambivalence
J. Paul Goode
Feb 05, 2019
This article argues that the sources of official and societal ambivalence towards civic nationhood in today’s Russia are found in the institutional instability and personalist dynamics of hybrid regime politics in the 1990s....
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